This issue of Endocrinology and Metabolism Clinics examines the timely topic of Lipidology. In addition to the New Recommendations - ACC/AHA Lipid Guidelines, the issue also includes Familial Hypercholesterolemia; LDL Apheresis; Lipids in Pregnancy and Women; Diabetes and Lipidology; Diabetic Dyslipidemia; Fatty Liver Disease; Lipids and HIV Disease; Residual Risk; and Statins' effects on diabetes, cognition, and liver safety.

This issue of Endocrinology and Metabolism Clinics, devoted to Lipids, is edited by Dr. Donald A. Smith. Articles in this issue include: Advanced Lipoprotein Testing; Improving Cardiovascular Risk Assessment: Coronary calcium scor and CT coronary imaging; Understanding HDL; Statin Strategies for Maximizing Public Health: benefits and harms; Cellular Cholesterol Regulation: SREBP and miRNA; Mediterranean Diet – the best diet for CV protection?; Pediatric Lipidology: An Earlier Approach; Newer LDL-lowering Therapies; and Statin Combination Therapies.

This timely, concise title provides an important update on clinical lipid management. Using information from recent clinical trials and in special populations, the book begins by offering an easy-to-read overview of LDL, HDL, and triglyceride metabolism and the genetics of lipid disorders. The link between inflammation and lipids, and how this relates to atherosclerosis development, is also addressed, as are the measures of subclinical atherosclerosis in patients with abnormal lipid levels. Lipid abnormalities in children, with a particular focus on vulnerable populations (with an emphasis on ethnicity and childhood obesity), are covered. The treatment goals and approaches for managing lipids in the clinic are thoroughly discussed, emphasizing the important role of statin use and addressing controversies of lipid management in special populations such as heart failure, end stage kidney disease and fatty liver disease. Of special note, an important update on how new HIV medications impact lipid levels is provided. In all, Lipid Management: From Basics to Clinic, is an invaluable, handy resource for understanding changes in lipids in different populations and for sharpening the clinical approach to managing complicated lipid cases.

In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Rachel Pessah-Pollack and Maria Papaleontiou bring their considerable expertise to the topic of Update on Endocrine Disorders During Pregnancy. In recent years, our understanding of endocrine disorders during pregnancy has greatly evolved and changed. In this issue, top experts provide updates on transgender reproductive health, PCOS management during pregnancy, hypertension, diabetes, congenital adrenal hyperplasia during pregnancy, and more. - Contains 13 relevant, practice-oriented topics including hyperthyroidism during pregnancy; pregnancy-related bone loss; challenges of lipid management during pregnancy; Cushing's disease; and more. - Provides in-depth clinical reviews on endocrine disorders during pregnancy, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Paul Hruz, is devoted to HIV and Endocrine Disorders. Articles in this issue include: Dyslipidemia and cardiovascular risk in HIV infection; Changes in nutritional concerns in HIV/AIDS; HIV Lipodystrophy: Lessons learned about adipose tissue and metabolic disorders; Hypogonadism in the HIV infected male; Gonadal function and reproductive health in women with HIV; Osteopenia, osteoporosis, and fracture risk with HIV infection and treatment; HIV-associated calcium and vitamin D abnormalities; Alterations in pancreatic islet function in HIV; Insulin resistance, glucose intolerance, and diabetes in HIV; Thyroid abnormalities in HIV; HPA axis/adrenal pathology in HIV; and Endocrinopathies in HIV-infected children.

This issue of Endocrinology and Metabolism Clinics of North America is devoted to Reproductive Endocrinology. Guest Editors Peter Lee, MD and Christopher P. Houk, MD have assembled a group of expert authors to review the following topics: Fertility Among Females and Males with Congenital Adrenal Hyperplasia (21-Hydroxylase Deficiency); Reproductive Issues for Turner Syndrome; Fertility and Reproduction Among Childhood Cancer Survivors; Fertility After Crypotochidism; Male Obesity and Fertility; Fertility Issues among Transgender Individuals; Fertility Preservation in Pediatrics; Polycystic Ovary Syndrome (PCOS); Fertility Issues for Patients With Delayed Puberty (Constitutional Delay, Functional Delay, and Hypogonadotropism); Varicocele; Testis Development and Reproduction in Klinefelters Syndrome; and Fertility Issues Among Those With Disorders of Sex Development.

In this issue of Endocrinology and Metabolism Clinics of North America, guest editor Dr. Osagie Ebekozien brings his considerable expertise to the topic of Type 1 Diabetes. Top experts in the field provide a timely update on type 1 diabetes care in children and adults, and provide recommendations for treatment and improving access to care. Contains 14 relevant, practice-oriented topics including type 1 diabetes population health improvement; access to care for type 1 diabetes; emerging technologies and therapeutics; social determinants of health (SDOH) in type 1 diabetes; COVID-19 and type 1 diabetes; and more. Provides in-depth clinical reviews on type 1 diabetes, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Sherouk Fouda and Joseph M. Pappachan bring their considerable expertise to the topic of Metabolic Associated Fatty Liver Disease. Top experts address the various ways metabolic associated fatty liver disease is related to other conditions such as diabetes, sarcopenia, PCOS, and more, as well as the management of MAFLD and cardiovascular implications. - Contains 12 practice-oriented topics including obstructive sleep apnea and MAFLD; the interlink between MAFLD and polycystic ovary syndrome; pregnancy and MAFLD; MAFLD and gut microbiota; and more. - Provides in-depth clinical reviews of metabolic associated fatty liver disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Connie B. Newman and Alan Chait bring their considerable expertise to the topic of Lipids: Update on Diagnosis and Management of Dyslipidemia. When untreated, dyslipidemia may have serious comorbidities; in this issue, top experts cover the evaluation and management of LDL cholesterol and high triglicerides in adults and children, providing practical information that will help physicians and other health care professionals treat their patients and improve outcomes. - Contains 13 practice-oriented topics including lipid and lipoprotein metabolism; measurement of lipids and advanced lipid testing; assessment of CVD risk; inherited forms of hypercholesterolemia; new and emerging therapies for dyslipidemia; and more. - Provides in-depth clinical reviews on diagnosis and management of dyslipidemia, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Endocrinology and Metabolism Clinics, edited by Dr. Robert Rapaport, is devoted to Pediatric Endocrinology. Articles in this issue include: Thyroid Cancer in Pediatrics; Gender and Sex Assignment; CAH Prenatal Diagnosis; Diabetes; Polycystic Ovarian Disease; Newborn Screening for X-linked ALD; Growth in Patients w/ Skeletal Dysplasia; Thyroid Imaging in Infants; Bariatric Surgery in Youth; Pituitary Imaging in Pediatrics; and Cardiac and Metabolic Features of GH Deficiency.