"I have been much impressed in teaching students by the fact that you can manifestly interest every member of a large class when you are teaching mental diseases clinically, while you fail to reach some of them by systematic descriptions. Direct appeals to the facts of nature, however fragmentary, make more impression on them than any amount of elaborate description. These considerations led me to publish the following lectures as a text-book for my students in the University of Edinburgh; and I venture to indulge the hope that it will also supply a want which I know many busy practitioners of medicine feel. The two hundred and sixty cases of mental disease which I describe and embody in those lectures may, I hope, assist some of my brethren in the profession in their treatment of a very obscure and troublesome class of diseases. In the selection of those cases, I had in view rather their applicability as good, ordinary types and guides than their rarity or their striking characters. The tendency in publishing mental cases has been to fix on wonderful rather than useful examples. To render the work complete as regards the wants of the American practitioner, Dr. Charles F. Folsom, with the assistance of Hollis R. Bailey, Esq., has added an appendix on the laws of the United States, and of the several States, relating to the custody of the insane"--Preface. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

A full-color, case-based review of the essentials of pathophysiology--covering all major organs and systems The goal of this trusted text is to introduce you to clinical medicine by reviewing the pathophysiologic basis of 120 diseases (and associated signs and symptoms) commonly encountered in medical practice. The authors, all experts in their respective fields, have provided a concise review of relevant normal structure and function of each body system, followed by a description of the pathophysiologic mechanisms that underlie several common diseases related to that system. Each chapter of Pathophysiology of Disease concludes with a collection of case studies and questions designed to test your understanding of the pathophysiology of each clinical entity discussed. These case studies allow you to apply your knowledge to specific clinical situations. Detailed answers to each case study question are provided at the end of the book. This unique interweaving of physiological and pathological concepts will put you on the path toward thinking about signs and symptoms in terms of their pathophysiologic basis, giving you an understanding of the "why" behind illness and treatment. Features 120 case studies (9 new) provide an opportunity for you to test your understanding of the pathophysiology of each clinical entity discussed Checkpoint questions provide review and appear in every chapter Updates and revisions throughout this new edition reflect the latest research and developments Numerous tables and diagrams encapsulate important information Updated references for each chapter topic Pathophysiology of Disease is a true must-have resource for medical students preparing for the USMLE Step 1 exam, as well as students engaged in their clerkship studies. House officers, nurses, nurse practitioners, physicians’ assistants, and allied health practitioners will find its concise presentation and broad scope a great help in facilitating their understanding of common disease entities.