Worldwide experience with the Lcs• mobile bearing total knee prosthesis has been unpar alleled both in terms of enduring popularity and outstanding long-term clinical results. Buechel and Pappas's design was based on the principles of; restoring anatomical joint function to as near normal as possible, minimising contact stresses to avoid wear and darn age to the bearing surfaces. and finally the idea that constraint should refiect the need for mobility, to avoid shear stresses and loosening of the implant. In 1977, the LCS® knee was implanted by Dr. Frederick Buechel. This was the first mobile bearing, tri-compartmental knee implant. This was also the first to successfully address the key issues ofloosening, wear and patello-femoral problems associated with earlier designs. The unique design solution was the creation of a common articulating geometry for the tibia and patella on the distal femoral surface. This resulted in a tibial and patellar articulation that was mobile in nature, but with an identical radius of curvature and conformity. The mobile bearing concept was considered sufficiently novel and unproven that the US FDA (Food & Drug Administration) required that it be validated in an Investigational Device Evaluation (IDE). An FDA IDE study involving 25 US surgeons was initiated in 1981. Validation of the clinical success of the device in this study resulted in FDA approval of the LCS, Knee (for cemented, tri-compartmental use) in 1985.

The main goal of the present book is to deal with the role of nanobiotechnology in skin, soft tissue and bone infections since it is difficult to treat the infections due to the development of resistance in them against existing antibiotics. The present interdisciplinary book is very useful for a diverse group of readers including nanotechnologists, medical microbiologists, dermatologists, osteologists, biotechnologists, bioengineers. Nanotechnology in Skin, Soft-Tissue, and Bone Infections is divided into four sections: Section I- includes role of nanotechnology in skin infections such as atopic dermatitis, and nanomaterials for combating infections caused by bacteria and fungi. Section II- incorporates how nanotechnology can be used for soft-tissue infections such as diabetic foot ulcer and other wound infections; Section III- discusses about the nanomaterials in artificial scaffolds bone engineering and bone infections caused by bacteria and fungi; and also about the toxicity issues generated by the nanomaterials in general and nanoparticles in particular. The readers will be immensely enriched by the knowledge of new and emerging nanobiotechnologies in a variety of platforms.

This book constitutes the full research papers and short monographs developed on the base of the refereed proceedings of the International Conference: Information and Communication Technologies for Research and Industry (ICIT 2020). The book brings accepted research papers which present mathematical modelling, innovative approaches and methods of solving problems in the sphere of control engineering and decision making for the various fields of studies: industry and research, energy efficiency and sustainability, ontology-based data simulation, theory and use of digital signal processing, cognitive systems, robotics, cybernetics, automation control theory, image and sound processing, image recognition, technologies, and computer vision. The book contains also several analytical reviews on using smart city technologies in Russia. The central audience of the book are researchers, industrial practitioners and students from the following areas: Adaptive Systems, Human–Robot Interaction, Artificial Intelligence, Smart City and Internet of Things, Information Systems, Mathematical Modelling, and the Information Sciences.

Intraoperative imaging technologies have taken an ever-increasing role in the daily practice of neurosurgeons and the increasing attention and interest necessitated international interaction and collaboration. The Intraoperative Imaging Society was formed in 2007. This book brings together highlights from the second meeting of the Intraoperative Imaging Society, which took place in Istanbul-Turkey from June 14 to 17, 2009. Included within the contents of the book is an overview of the emergence and development of the intraoperative imaging technology as well as a glimpse on where the technology is heading. This is followed by in detail coverage of intraoperative MRI technology and sections on intraoperative CT and ultrasonography. There are also sections on multimodality integration, intraoperative robotics and other intraoperative technologies. We believe that this book will provide an up-to date and comprehensive general overview of the current intraoperative imaging technology as well as detailed discussions on individual techniques and clinical results.

The latest update to Bela Liptak's acclaimed "bible" of instrument engineering is now available. Retaining the format that made the previous editions bestsellers in their own right, the fourth edition of Process Control and Optimization continues the tradition of providing quick and easy access to highly practical information. The authors are practicing engineers, not theoretical people from academia, and their from-the-trenches advice has been repeatedly tested in real-life applications. Expanded coverage includes descriptions of overseas manufacturer's products and concepts, model-based optimization in control theory, new major inventions and innovations in control valves, and a full chapter devoted to safety. With more than 2000 graphs, figures, and tables, this all-inclusive encyclopedic volume replaces an entire library with one authoritative reference. The fourth edition brings the content of the previous editions completely up to date, incorporates the developments of the last decade, and broadens the horizons of the work from an American to a global perspective. Béla G. Lipták speaks on Post-Oil Energy Technology on the AT&T Tech Channel.

Safe Passage: Astronaut Care for Exploration Missions sets forth a vision for space medicine as it applies to deep space voyage. As space missions increase in duration from months to years and extend well beyond Earth's orbit, so will the attendant risks of working in these extreme and isolated environmental conditions. Hazards to astronaut health range from greater radiation exposure and loss of bone and muscle density to intensified psychological stress from living with others in a confined space. Going beyond the body of biomedical research, the report examines existing space medicine clinical and behavioral research and health care data and the policies attendant to them. It describes why not enough is known today about the dangers of prolonged travel to enable humans to venture into deep space in a safe and sane manner. The report makes a number of recommendations concerning NASA's structure for clinical and behavioral research, on the need for a comprehensive astronaut health care system and on an approach to communicating health and safety risks to astronauts, their families, and the public.

This first book to critically summarize the latest achievements and emerging applications within this interdisciplinary topic focuses on one of the most important types of detectors for elementary particles and photons: resistive plate chambers (RPCs). In the first part, the outstanding, international team of authors comprehensively describes and presents the features and design of single and double-layer RPCs before covering more advanced multi-layer RPCs. The second part then focuses on the application of RPCs in high energy physics, materials science, medicine and security. Throughout, the experienced authors adopt a didactic approach, with each subject presented in a simple way, increasing in complexity step by step.

"Take away my knee pain and give me better motion". This is what the arthritic patient expects from a Total Knee Arthroplasty (TKA). By virtue of standardization of the TKA procedure, surgeons can nowadays solve the pain issue for the majority of the patients. Restoration of function is a goal of a different order and forms the scope of this book. The editors confronted today's leading knee surgeons with the limitations of current surgical techniques and technology. They challenged them to define new thresholds of functional capacity after Total Knee Arthroplasty. "A Guide to Get Better Performance in TKA" describes the cutting edge in surgical techniques, prosthetic design and achievement of excellent function for these patients.