Strictly off limits to the public, Plum Island is home to virginal beaches, cliffs, forests, ponds -- and the deadliest germs that have ever roamed the planet. Lab 257 blows the lid off the stunning true nature and checkered history of Plum Island. It shows that the seemingly bucolic island in the shadow of New York City is a ticking biological time bomb that none of us can safely ignore. Based on declassified government documents, in-depth interviews, and access to Plum Island itself, this is an eye-opening, suspenseful account of a federal government germ laboratory gone terribly wrong. For the first time, Lab 257 takes you deep inside this secret world and presents startling revelations on virus outbreaks, biological meltdowns, infected workers, the periodic flushing of contaminated raw sewage into area waters, and the insidious connections between Plum Island, Lyme disease, and the deadly West Nile virus. The book also probes what's in store for Plum Island's new owner, the Department of Homeland Security, in this age of bioterrorism. Lab 257 is a call to action for those concerned with protecting present and future generations from preventable biological catastrophes.

A riveting thriller reminiscent of The Hot Zone, this true story dives into the mystery surrounding one of the most controversial and misdiagnosed conditions of our time—Lyme disease—and of Willy Burgdorfer, the man who discovered the microbe behind it, revealing his secret role in developing bug-borne biological weapons, and raising terrifying questions about the genesis of the epidemic of tick-borne diseases affecting millions of Americans today. While on vacation on Martha’s Vineyard, Kris Newby was bitten by an unseen tick. That one bite changed her life forever, pulling her into the abyss of a devastating illness that took ten doctors to diagnose and years to recover: Newby had become one of the 300,000 Americans who are afflicted with Lyme disease each year. As a science writer, she was driven to understand why this disease is so misunderstood, and its patients so mistreated. This quest led her to Willy Burgdorfer, the Lyme microbe’s discoverer, who revealed that he had developed bug-borne bioweapons during the Cold War, and believed that the Lyme epidemic was started by a military experiment gone wrong. In a superb, meticulous work of narrative journalism, Bitten takes readers on a journey to investigate these claims, from biological weapons facilities to interviews with biosecurity experts and microbiologists doing cutting-edge research, all the while uncovering darker truths about Willy. It also leads her to uncomfortable questions about why Lyme can be so difficult to both diagnose and treat, and why the government is so reluctant to classify chronic Lyme as a disease. A gripping, infectious page-turner, Bitten will shed a terrifying new light on an epidemic that is exacting an incalculable toll on us, upending much of what we believe we know about it.

In this “engrossing, well-documented, and highly readable” (San Francisco Chronicle) New York Times bestseller, three veteran reporters draw on top sources inside and outside the U.S. government to reveal Washington's secret strategies for combating germ warfare and the deadly threat of biological and chemical weapons. Today Americans have begun to grapple with two difficult truths: that there is no terrorist threat more horrifying—and less understood—than germ warfare, and that it would take very little to mount a devastating attack on American soil. Featuring an inside look at how germ warfare has been waged throughout history and what form its future might take (and in whose hands), Germs reads like a gripping detective story told by fascinating key figures: American and Soviet medical specialists who once made germ weapons but now fight their spread, FBI agents who track Islamic radicals, the Iraqis who built Saddam Hussein's secret arsenal, spies who travel the world collecting lethal microbes, and scientists who see ominous developments on the horizon. With clear scientific explanations and harrowing insights, Germs is a vivid, masterfully written—and timely—work of investigative journalism.

This highly original work presents laboratory science in a deliberately skeptical way: as an anthropological approach to the culture of the scientist. Drawing on recent work in literary criticism, the authors study how the social world of the laboratory produces papers and other "texts,"' and how the scientific vision of reality becomes that set of statements considered, for the time being, too expensive to change. The book is based on field work done by Bruno Latour in Roger Guillemin's laboratory at the Salk Institute and provides an important link between the sociology of modern sciences and laboratory studies in the history of science.

Exotic Animal Laboratory Diagnosis is a practical, user-friendly guide to diagnostic testing in a wide range of exotic species. Offers complete information on obtaining samples, performing tests, and interpreting laboratory results in exotic animals Presents information on each species using a similar format for easy access Emphasizes details on clinical biochemistries, urinalysis, and common laboratory diagnostic tests not found in other resources Draws together information on selecting, performing, and using diagnostic tests into a single easy-to-use resource Covers a wide range of species, including small mammals, primates, reptiles, aquatic animals, and wild, laboratory, and pet birds

Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and different anesthetic agents that are used in performing an experiment on animals. The book also discusses the profound effects of anesthesia on the physiological aspect of the animals' body systems, such as hypothermia and respiratory depression. The book addresses the proper management and care that should be provided for the animals that undergo anesthesia. Furthermore, it covers different anesthetic procedures that should be used on various kinds of small animals intended for laboratory experiments. The main goal of this book is to provide information about the different anesthetic agents used in experiments, and the proper standards to follow when using anesthetics on lab animals.• New edition provides new information on anesthesia and analgesia, and has an extensively revised and updated bibliography• Provides a balanced consideration of the needs of scientific research and the welfare of laboratory animals• Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area• Provides rapid, easily accessed information using tabulated summaries• Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely• Provides sufficient depth for the more experienced anesthetist moving to this field

Inside the Hot Zone 'is an insider's account of one of the most dangerous workplaces on earth: 'the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) in Fort Detrick, Maryland. Retired U.S. Army Col. Mark G. Kortepeter, a leading biodefense expert, recounts his journey from the lecture hall to the role of department chief, to the battlefield, to the Biosafety Level-4 maximum containment lab, and finally, to the corner office.During Kortepeter's seven and a half years in leadership at USAMRIID, the United States experienced some of the most serious threats in modern germ warfare, including the specter of biological weapons during the Iraq War, the anthrax letters sent after 9/11, and a little-known crisis involving a presumed botulism attack on the president of the United States. Inside the Hot Zone 'is a shocking, frightening eye-opener as Kortepeter describes in gripping detail how he and his USAMRIID colleagues navigated threats related to anthrax, botulism, smallpox, Lassa, and Ebola.Kortepeter crafts a rich and riveting narrative as he wrestles with life-and-death decisions managing biological weapon exposures. The stories are real, but they could just as easily serve as plotlines in popular fiction or Hollywood thrillers. He gives the reader a seat at the table as each 'crisis unfolds, with an unvarnished and personal perspective on the dangers, the drama, the fear, the frustrations, the irony, and the uncertainty he encountered as a physician in the role of "Biodefender."'

The definitive history of America’s greatest incubator of innovation and the birthplace of some of the 20th century’s most influential technologies “Filled with colorful characters and inspiring lessons . . . The Idea Factory explores one of the most critical issues of our time: What causes innovation?” —Walter Isaacson, The New York Times Book Review “Compelling . . . Gertner's book offers fascinating evidence for those seeking to understand how a society should best invest its research resources.” —The Wall Street Journal From its beginnings in the 1920s until its demise in the 1980s, Bell Labs-officially, the research and development wing of AT&T-was the biggest, and arguably the best, laboratory for new ideas in the world. From the transistor to the laser, from digital communications to cellular telephony, it's hard to find an aspect of modern life that hasn't been touched by Bell Labs. In The Idea Factory, Jon Gertner traces the origins of some of the twentieth century's most important inventions and delivers a riveting and heretofore untold chapter of American history. At its heart this is a story about the life and work of a small group of brilliant and eccentric men-Mervin Kelly, Bill Shockley, Claude Shannon, John Pierce, and Bill Baker-who spent their careers at Bell Labs. Today, when the drive to invent has become a mantra, Bell Labs offers us a way to enrich our understanding of the challenges and solutions to technological innovation. Here, after all, was where the foundational ideas on the management of innovation were born.

An arresting book about the incredible dangers and implications of genetic engineering harnessed to biological warfare.

Virtualization is a skill that most IT or security pros take for granted. The sheer number of choices and requirements can be a daunting challenge to face for beginners and veterans alike. With this book, you'll learn how to build a robust, customizable virtual environments suitable for both a personal home lab, as well as a dedicated office training environment. You will learn how to: - Understand the mechanics of virtualization and how they influence the design of your lab - Build an extensive baseline lab environment on any one of five commonly used hypervisors (VMware vSphere Hypervisor, VMware Fusion, VMware Workstation, Oracle Virtualbox, and Microsoft Client Hyper-V) - Harden your lab environment against VM escapes and other security threats - Configure the pfSense firewall distribution to provide security, segmentation, and network services to your virtual lab - Deploy either Snort or Suricata open-source IDS platforms in IPS mode to further enhance the flexibility, segmentation and security of your lab network - Deploy Splunk as a log management solution for your lab - Reconfigure the provided baseline lab environment to better suit your individual needs Easy to follow steps and illustrations provide detailed, comprehensive guidance as you build your custom-tailored lab. Both IT and security professionals need practice environments to better hone their craft. Learn how to build and maintain your own with Building Flexible Virtual Machine Labs