Introductory Practical Biochemistry, designed to cater to the requirements of students of biochemistry, microbiology, molecular biology, cellular biology etc. covers modern techniques employed for qualitative and quantitative analysis of biomolecules. The techniques for genetic transformation etc., have been included to give preliminary information to the beginners in the field of genetic engineering. Radioisotopic and immunological techniques also find a place in the book. Each chapter starts with introductory details of the techniques followed by simple laboratory exercises. The book provides concise information on theoretical and practical aspects of the techniques employed in biochemical studies for the Undergraduate and Postgraduate students, Instructors and Research workers.

This comprehensive text offers a solid introduction to the biochemical principles and skills required for any researcher applying computational tools to practical problems in biochemistry. Each chapter includes an introduction to the topic, a review of the biological concepts involved, a discussion of the programming and applications used, key references, and problem sets and answers. Providing detailed coverage of biochemical structures, enzyme reactions, metabolic simulation, genomic and proteomic analyses, and molecular modeling, this is the perfect resource for students and researchers in biochemistry, bioinformatics, bioengineering and computational science.

Uniquely integrates the theory and practice of key experimental techniques for bioscience undergraduates. Now includes drug discovery and clinical biochemistry.

Das erfolgreiche Werk des jungen, kreativen Autors jetzt in aktualisierter und korrigierter Auflage! Der Text wurde um Fragenkomplexe und Übungsbeispiele, teils mit Lösungen, erweitert; dies empfiehlt ihn besonders zur Ergänzung einer Vorlesung.

The new edition of the best-selling Lecture Notes title is aconcise introduction to clinical biochemistry that presents thefundamental science underpinning common biochemical investigationsused in clinical practice. Lecture Notes: Clinical Biochemistry allows thereader to make efficient and informed use of the diagnosticservices offered by their clinical biochemistry department. Theresult is a text that serves as a reference to the practitioner aswell as the student. The book takes a system-based approach, withthe underlying physiological rationale for any test explained inthe context of disruption by disease. This leads naturally to anintegrated and practical understanding of biochemicaldiagnostics. Including multiple choice questions (MCQs) alongsideend-of-chapter case studies to help develop test-selection skills,Lecture Notes: Clinical Biochemistry provides the essentialbackground to biochemical investigations and is an ideal coursecompanion and revision guide for medical students, junior doctorson the Foundation Programme, general practitioners, and nurses andlaboratory technicians.

Molecular simulation is a powerful tool in materials science, physics, chemistry and biomolecular fields. This updated edition provides a pragmatic introduction to a wide range of techniques for the simulation of molecular systems at the atomic level. The first part concentrates on methods for calculating the potential energy of a molecular system, with new chapters on quantum chemical, molecular mechanical and hybrid potential techniques. The second part describes methods examining conformational, dynamical and thermodynamical properties of systems, covering techniques including geometry-optimization, normal-mode analysis, molecular dynamics, and Monte Carlo simulation. Using Python, the second edition includes numerous examples and program modules for each simulation technique, allowing the reader to perform the calculations and appreciate the inherent difficulties involved in each. This is a valuable resource for researchers and graduate students wanting to know how to use atomic-scale molecular simulations. Supplementary material, including the program library and technical information, available through www.cambridge.org/9780521852524.

"As will be seen, there is not much missing here. I thought that the sections were well balanced, with rarely too much or too little on a given topic...This is a text to be welcomed by both teachers and students." BIOCHEMISTRY & MOLECULAR BIOLOGY EDUCATION (on the first edition) The second edition of this successful textbook explains the basic principles behind the key techniques currently used in the modern biochemical laboratory and describes the pros and cons of each technique and compares one to another. It is non-mathematical, comprehensive and approachable for students who are not physical chemists. A major update of this comprehensive, accessible introduction to physical biochemistry. Includes two new chapters on proteomics and bioinformatics. Introduces experimental approaches with a minimum of mathematics and numerous practical examples. Provides a bibliography at the end of each chapter. Written by an author with many years teaching and research experience, this text is a must-have for students of biochemistry, biophysics, molecular and life sciences and food science.

Clinical biochemistry is an analytical and interpretative science. The analytical part involves the determination of the level of chemical components in body fluids and tissues. The interpretative part examines these results and uses them in the diagnosis of disease, the screening for susceptibility to specific diseases, and the monitoring of the progress of treatment. This book is designed to cover the major techniques and analytical instruments used in clinical biochemistry.Each chapter of this book is based on a specific technique, or techniques, with associated instrumentation. These are discussed in some detail. A historical introduction is included for most of the techniques, and the current uses of the techniques are presented. Following that is a series of practical exercises. The first exercises in most of the chapters are a general introduction to the technique, leading to those with a clinical bias. Where applicable, the clinical practical exercises are associated with a case history and/or the discussion of the relevance of the assay to diagnosis and prognosis and to the monitoring of recovery. Each chapter concludes with a selection of appropriate references.