Gives an introduction to various aspects of drug use in renal failure. Covering a variety of diseases affecting the kidneys, this work discusses the disease process and treatment. It also addresses the role of the pharmacist in patient care, and case studies and questions and answers are included at the end of each chapter.

This book started out as a "Manual. " The idea was to offer straightforward instruction on how to handle patients in whom renal function is altered by intrinsic as well as systemic or extrarenal disease. While we have attempted to provide simple approaches to most conditions, we have gone beyond that and offer here more detailed description of pathophysiology, diagnosis and therapy. Thus, the "Manual" has become a Handbook. In so doing we hope we have widened the audience for which the book may be useful. As it now stands, we envision that students, house staff, nephrology trainees, nephrologists, primary-care physicians, and nurses of specialized units, interested in kidney-related disturbances and in alterations of the composi tion of the extracellular fluid, will benefit from reading the Handbook. While providing a rational background for the treatments outlined, each author has attempted to narrate the reasons why such therapy is utilized. Frequently, the information is provided in tables and figures to which ready reference can be made. The flow-chart approach has also been utilized to illustrate pathophysiological sequence or steps in therapy. In most instances, the discussion of pathophysiology has been limited to what is widely ac cepted rather than treading into anything controversial, unless the nature of the problem or the nature of our knowledge is ambiguous.

This first volume of an exciting new book series offers a comprehensive and logically organized introduction to clinical pharmacy as applied to renal medicine. The volume opens with a review of renal pharmacokinetics: absorption; distribution; metabolism; and elimination, as well as drug dosing in renal impairment, and important knowledge specific to aging and renal impairment. Acute kidney injury receives extensive attention, including pre-renal, intra-renal, and post-renal injuries. The book also outlines the role of clinical pharmacy in chronic kidney disease and end stage renal failure. Additional chapters provide detailed information on the methods and pharmacokinetics of renal dialysis, and the epidemiology and management of drug-induced nephrotoxicity. The Advanced Clinical Pharmacy series provides a review of core pharmaceutical concepts, a foundation for optimizing pharmacotherapy, and an introduction to advanced clinical practice. The editors and contributors are international experts who distill the core knowledge of each specialty. The books offer real-world insights to benefit both new practitioners, and experienced pharmacists exploring new areas of clinical pharmacy

The Systems of the Body series has established itself as a highly valuable resource for medical and other health science students following today's systems-based courses. Now thoroughly revised and updated in this third edition, each volume presents the core knowledge of basic science and clinical conditions that medical students need, providing a concise, fully integrated view of each major body system that can be hard to find in more traditionally arranged textbooks or other resources. Multiple case studies help relate key principles to current practice, with links to clinical skills, clinical investigation and therapeutics made clear throughout. Each (print) volume also now comes with access to the complete, enhanced eBook version, offering easy anytime, anywhere access - as well as self-assessment material to check your understanding and aid exam preparation. The Renal System provides highly accessible coverage of the core basic science principles in the context of clinical case histories, giving the reader a fully integrated understanding of the system and its major diseases. - Introduction to the Renal System - Body Fluids, Nephron Function and Diuretics - Water Balance and Regulation of Osmolality - Acid–Base Balance and Regulation of pH - Glomerular Filtration and Acute Kidney Injury - Proteinuria and the Nephrotic Syndrome - Glomerulonephritis and the Acute Nephritic Syndrome - Diabetic Nephropathy and Chronic Kidney Disease - Kidney Failure and Replacement of Renal Function - Hypertension and the Kidney - Pregnancy and the Kidney - Urinary Tract Obstruction and Stones - Renal Masses, Cysts and Urinary Tract Tumours - Drugs and the Kidney Systems of the Body Series: - The Renal System - The Musculoskeletal System - The Nervous System - The Digestive System - The Endocrine System - The Respiratory System - The Cardiovascular System

This invaluable guide, endorsed by the UKMi and reflecting the extensive experience of the UK Renal Pharmacy Group, features drug monographs guiding physicians in how to prescribe, prepare, and administer drugs to patients with different levels of kidney function and when undergoing renal replacement therapy. It has been fully updated for this fifth edition to include up to 100 additional drugs, while maintaining the clear structure and format that is easy to use and simple to follow in the busy clinical setting. It continues to offer support and guidance to health care professionals enabling them to prescribe medications to their renal patients appropriately and safely.

This companion to Brenner and Rector's THE KIDNEY reviews the management and treatment of renal disease, and the present consensus regimens, while placing a special emphasis on the specifics of treatment. Includes a three part format: an introduction covering clinical features, pathology, and pathophysiology; a section on rationale of therapy and review of the results of clinical trials; and a section discussing specific recommendations.