Our world is facing unprecedented technological development, which affects all the sectors of society. The 4th industrial revolution has brought numerous advances that are currently integrated in our daily life, including artificial intelligence (A.I.), internet of things (IoT), genetic engineering, 3D-printing and robotics. The health care sector is one of the most impacted by these technologies of the so-called digital era. From the simple advent of medical records to robotic surgery, health care has significantly changed from the XX to XXI century and is constantly changing, incorporating novel technologies. Nephrology is itself an innovative branch of medicine, created as a discipline in the 1960s, with breakthrough inventions, such as the dialysis machine, which made it possible to prolong life of those who suffer from chronic kidney disease; kidney transplant, with point-of-care immunosuppression that favours maintenance of kidney allografts for long years; kidney biopsy, which made it possible to discover the mysteries of glomerulonephritis and nephropathology. Novel technologies, such as A.I., IoT, robotics, stem cells, 3D-printing, mHealth, eHealth and several others are starting to be applied in nephrology, with promising results. It is possible that a great part of these technologies will become routinely available in clinical practice, and the burden of kidney diseases will significantly decrease once prevention, prediction, detection, monitoring and treatment of kidney diseases are more precise, with patients taking part in the process and becoming more and more connected. This book gathers essential information on the technologies that have been applied in nephrology and that can be applied in the future, with real possibilities of improving the care of kidney diseases. At first glance, this work is directed to the entire nephrology community and all the healthcare professionals that deal with kidney diseases. Researchers from different fields, not directly linked to nephrology, may also be interested in the book since many of the topics presented are related to other areas and serve as examples of their uses in medicine, such as artificial intelligence, robotics, and big data. Finally, the content provides an important resource to medical students, discussing technologies that will certainly be integrated in their professional practice.

Recognize market opportunities, master the design process, and develop business acumen with this 'how-to' guide to medical technology innovation. Outlining a systematic, proven approach for innovation - identify, invent, implement - and integrating medical, engineering, and business challenges with real-world case studies, this book provides a practical guide for students and professionals.

This book covers all key aspects of critical care in pediatric nephrology, including acute dialysis in sick children. It also provides detailed protocols for managing fluid and electrolyte balance and dialysis in children in intensive care. In addition, this quick guide discusses innovations in pediatric renal replacement therapy technologies, such as plasma exchange, CARPEDIEM, NIDUS and aquadex. This is a go-to book for intensivists, physicians and trainees working in pediatric intensive care units.

Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.

Despite constant significant advances, cardiovascular as well as more general outcomes of hemodialysis treatment remain unsatisfactory. The introduction of innovative 'high retention onset' membranes has led to the development of a new treatment modality called 'expanded hemodialysis' (HDx), which is the focus of this book. This new therapy is likely to benefit end-stage kidney disease patients, thanks to enhanced removal of molecules retained by current dialysis techniques. HDx is simple to set up and application does not require special hardware or specific nursing skills. This book contains emerging evidence and fascinating new hypotheses on HDx. It is highly recommended for all physicians and healthcare professionals who are caring for dialysis patients and are seeking innovation and improved care solutions. It will also be of considerable interest to students and fellows.

This book analyses the latest advancements in the very important topic of vascular access in haemodialysis patients. Dialysis patients are a continuously growing population all over the world. Long-lasting and well-functioning vascular access is a life-line for these patients. Therefore, successful creation and appropriate management of vascular access is of the utmost importance. This book comprehensively reviews the different and most important issues related to vascular access management. It has 33 chapters discussing a wide variety of the most important topics including: principles of access creation in adults, paediatric and geriatric populations; types of anaesthesia; central venous catheters; early cannulation and hybrid vascular grafts; possible complications and principles of their management; quality of life in dialysis patients; etc. It consists of a review as well as original articles pertaining to the subject matter. The book also describes rare forms of arterio-venous accesses, last resort dialysis accesses, and life-saving approaches for the most challenging patients. All of the authors are experts in the field. They represent 16 different countries across the world, making this book especially unique. The chapters are well-illustrated, making them easy to read. We hope that this book will offer the most contemporary and useful information for specialists involved in haemodialysis therapy.

This book provides a complete guide to the evaluation, care, and follow-up of living kidney donors. Living donor kidney transplantation is established as the best treatment option for kidney failure. However, despite the tremendous benefits of living donation to recipients and society, the outcomes and optimal care of donors themselves have received relatively less attention. Fortunately, things are changing – including recent landmark developments in living donor risk assessment, policy and guidance. This volume offers authoritative, evidence-based guidance on the full range of clinical scenarios encountered in the evaluation and care of living kidney donors. The approach to key elements of risk assessment, ethical considerations and informed consent is accompanied by recommendations for patient-centered care before, during, and after donation. Advocacy initiatives and policies to remove disincentives to donation and advance a defensible system of practice are also discussed. General and transplant nephrologists, as well as related allied health professionals, can look to this book as a comprehensive resource addressing contemporary clinical topics in the practice of living kidney donation.

The leading Textbook on the subject. A completely rewritten and up-to-date fifth edition, based upon the highly respected fourth edition, edited by C. Jacobs, C.M. Kjellstrand, K.M. Koch and J.F. Winchester. This new edition is truly global in scope and features the contributions of the top experts from around the world.

This publication is a collection of the papers presented at the 'First International Course on Hemodialysis Technology', Vicenza, June 2002: It covers a wide range of topics, including aspects of vascular access and new forms of monitoring access function. Moreover, anticoagulation strategies and antimicrobial treatment are debated, with special emphasis on temporary catheters and prosthetic devices.Membrane composition and structure, their methods of sterilization and performance are discussed by experts and manufacturers, bringing together in a unique way science, theory and manufacturing procedures. The same synthesis is achieved with respect to hemodialyzers, adsorbent devices, dialysis techniques and machines. A new issue is the possibility of computer-assisted data collection and management: This subject is discussed by experts in electronic data management, together with managers of large dialysis networks, concentrating on matters of quality assurance and continuous quality improvement programs.Special attention is given to dialysate and water purity since this is the starting point for newer dialytic techniques such as online hemodiafiltration. Moreover, the results obtained from the IDOPPS study are incorporated into the discussion of different practice patterns and anemia management. Finally, future trends are explored including automatic sensors and biofeedback monitors.Covering various aspects of hemodialysis technology, this book will be a helpful tool for physicians and nurses, both for education and information.

Unlock the secret to groundbreaking innovation with this game-changing guide Innovation means putting ideas to work. It is a discipline that can be learned, practiced, and leveraged to propel meaningful transformation and sustainable success, and it is proving to be the margin of difference in the largest concentrated sector of our economy: healthcare. This is where the stakes may be highest because the transcendent ideas that come from the patient bedside or laboratory bench don’t just translate to a bottom line, they improve and extend human life. Since its inception in 1921, Cleveland Clinic has been at the forefront of life-saving innovations in healthcare, pioneering a new model of care, advancing surgical techniques, and developing cutting-edge medical technologies. It has revolutionized the industry with a proven and tested working model for mission-driven, results-oriented success—one that is applicable to industries beyond healthcare. In Innovation the Cleveland Clinic Way, Thomas J. Graham, MD, describes the Clinic’s unique approach. Learn: • How to align the innovation strategy with your organization’s mission • How to identify your organization’s innovation assets and put them to work • How to foster collaboration within and across teams to spark creative ideation • The process of taking “napkin ideas” through successful commercialization • The most common innovation pitfalls and how to avoid and address them • Cleveland Clinic’s 10 commandments of innovation and the six degrees of innovation Packed with enterprising solutions and inspiring examples, this practical guide will equip any individual or institution seeking to affect purposeful transformation. Use these best practices to put ideas to work and turn yours into a high-innovation organization. Thomas J. Graham, MD, is the Chief Innovation Officer of Cleveland Clinic and Vice Chairman of Orthopedic Surgery. A prolific inventor with nearly 50 worldwide patents and a serial entrepreneur, he is a renowned orthopaedic surgeon whose practice is the premier destination for the care of the professional athlete’s hand and wrist. He is regularly recognized as one of “America’s Best Doctors.”