Innovative medical devices have helped reduce the burden of illness and injury and improve the quality of life for countless children. Mechanical ventilators and other respiratory support devices rescue thousands of fragile newborns every year. Children who once would have died of congenital heart conditions survive with the aid of implanted pacemakers, mechanical heart valves, and devices that close holes in the heart. Responding to a Congressional request, the Institute of Medicine assesses the system for postmarket surveillance of medical devices used with children. The book specifically examines: The Food and Drug Administration's monitoring and use of adverse event reports The agency's monitoring of manufacturers' fulfillment of commitments for postmarket studies ordered at the time of a device's approval for marketing The adequacy of postmarket studies of implanted devices to evaluate the effects of children's active lifestyles and their growth and development on device performance Postmarket surveillance of medical devices used with children is a little investigated topic, in part because the market for most medical products is concentrated among older adults. Yet children differ from adults, and their special characteristics have implications for evaluation and monitoring of the short- and long-term safety and effectiveness of medical devices used with young patients.

This comprehensive handbook provides an overview of key theoretical perspectives, concepts, and methodological approaches that, while applied to diverse phenomena, are united in their general approach to the study of lives across age phases. In surveying the wide terrain of life course studies with dual emphases on theory and empirical research, this important reference work presents probative concepts and methods and identifies promising avenues for future research.

The MediFocus Guidebook on Smoking Cessation is the most comprehensive, up-to-date source of information available. You will get answers to your questions, including standard and alternative treatment options, leading doctors, hospitals and medical centers that specialize in Smoking Cessation, results of the latest clinical trials, support groups and additional resources, and promising new treatments on the horizon. This one of a kind Guidebook offers answers to your critical health questions including the latest treatments, clinical trials, and expert research; high quality, professional level information you can trust and understand culled from the latest peer-reviewed journals; and a unique resource to find leading experts, institutions, and support organizations including contact information and hyperlinks. This Guidebook was updated on January 17, 2012.

Health Sciences & Professions

A new edition of the classic guide to the use of statistics in medicine, featuring examples from articles in the New England Journal of Medicine Medical Uses of Statistics has served as one of the most influential works on the subject for physicians, physicians-in-training, and a myriad of healthcare experts who need a clear idea of the proper application of statistical techniques in clinical studies as well as the implications of their interpretation for clinical practice. This Third Edition maintains the focus on the critical ideas, rather than the mechanics, to give practitioners and students the resources they need to understand the statistical methods they encounter in modern medical literature. Bringing together contributions from more than two dozen distinguished statisticians and medical doctors, this volume stresses the underlying concepts in areas such as randomized trials, survival analysis, genetics, linear regression, meta-analysis, and risk analysis. The Third Edition includes: Numerous examples based on studies taken directly from the pages of the New England Journal of Medicine Two added chapters on statistics in genetics Two new chapters on the application of statistical methods to studies in epidemiology New chapters on analyses of randomized trials, linear regression, categorical data analysis, meta-analysis, subgroup analyses, and risk analysis Updated chapters on statistical thinking, crossover designs, p-values, survival analysis, and reporting research results A focus on helping readers to critically interpret published results of clinical research Medical Uses of Statistics, Third Edition is a valuable resource for researchers and physicians working in any health-related field. It is also an excellent supplemental book for courses on medicine, biostatistics, and clinical research at the upper-undergraduate and graduate levels. You can also visit the New England Journal of Medicine website for related information.

How does the disintegration of the Soviet system help us to understand the character of library and information institutions and practices within post-soviet space? This title brings together diverse reflective essays, reports and empirical analyses of the changing character of the post-soviet library world to address the question.

The use of medications and multiple medications becomes more prevalent with increasing age. This pilot study explored the relationship between poly-pharmacy and driving functioning through separate but related research activities. A patient-level administrative claims database containing prescription information as well as E-codes identifying the incidence of motor vehicle injuries was mined, yielding combinations of drugs that became inclusion criteria in a following field study of driver performance among 44 older adults (range: 57 to 89; mean: 79). The relationship between medication usage and each of these outcome measures was examined in descriptive data summaries and regression analyses. Illus. A print on demand report.

Health Sciences & Professions

Real-life examples from the author's experience illuminate a step-by-step plan that can help entrepreneurial leaders achieve their goals. Entrepreneurial leaders are in need of a practical compass, and this book gives them just that. Combining principles of leadership and entrepreneurship, the guide covers basic concepts and pertinent issues for leaders at all levels and does so in a manner that is at once lively, relevant, and entertaining. Drawing on the best thinking from both business and academia, the book irrefutably demonstrates the connection between skilled leadership and organizational effectiveness and performance. Readers are provided with two easy-to-follow models that are applicable to all types of organizations. The Opportunity Model (Part I) shows exactly how to identify business-generating opportunities, while the Enduring Leadership Model (Part II) outlines the author's unique leadership principles, what he calls "Personal" and "Professional" Leadership. Used together, these two models give today's entrepreneurial leaders the real-life tools they need to succeed. To illustrate what works—and what doesn't—the author takes readers inside the highly volatile beverage industry and shares his greatest successes and failures running Adirondack Beverages, a company that still thrives today based on principles instilled more than 20 years ago.