This groundbreaking book describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients. It reveals fascinating insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. Structured around the examples of HIV/AIDS and hepatitis B, Nowak and May show how mathematical models can help researchers to understand the detailed dynamics of infection and the effects of antiviral therapy. Models are developed to describe the dynamics of drug resistance, immune responses, viral evolution and mutation, and to optimise the design of therapy and vaccines. - ;We know, down to the tiniest details, the molecular structure of the human immunodeficiency virus (HIV). Yet despite this tremendous accomplishment, and despite other remarkable advances in our understanding of individual viruses and cells of the immune system, we still have no agreed understanding of the ultimate course and variability of the pathogenesis of AIDS. Gaps in our understanding like these impede our efforts towards developing effective therapies and preventive vaccines. Martin Nowak and Robert M May describe the emerging field of theoretical immunology in this accessible and well- written text. Using mathematical modelling techniques, the authors set out their ideas about how populations of viruses and populations of immune system cells may interact in various circumstances, and how infectious diseases spread within patients. They explain how this approach to understanding infectious diseases can reveal insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. The book is structured around the examples of HIV/AIDS and Hepatitis B virus, although the approaches described will be more widely applicable. The authors use mathematical tools to uncover the detailed dynamics of the infection and the effects of antiviral therapy. Models are developed to describe the emergence of drug resistance, and the dynamics of immune responses, viral evolution, and mutation. The practical implications of this work for optimisation of the design of therapy and vaccines are discussed. The book concludes with a glance towards the future of this fascinating, and potentially highly useful, field of study. - ;... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host - Nature

In this book, a breakdown of the life and work of some of history's pioneers in the study of immunologists and virologists are thoroughly explored. As the world becomes more connected and bacteria become more antibiotic resistant, the importance of research within these two fields is becoming dyer. MRSA, Zika, SARS, and Ebola are just some of the recent outbreaks that have affected our communities. This opportune volume provides excellent biographical sketches for trailblazers in this area of science and will inspire readers to explore the top scientific contributors of the 21st century.

The study of viruses is known as virology. It focuses on the structure, evolution and behavior of viruses. Studying them is vital, as they cause various infectious diseases like dengue, yellow fever, smallpox, etc. The classification of viruses is done on the basis of the host that they infect, like fungal viruses, bacteriophages, animal viruses, etc. This book attempts to assist those with a goal of delving into the field of virology. Coherent flow of topics, student-friendly language and extensive use of examples make this textbook an invaluable source of knowledge.

Resumen: Offers an integrated view of principal aspects of immune response to all types of infectious agents. Deals with the immune system primarily as a host defense system. Various infectious agents and diseases are integrated under general topics rather than treated in separate chapters.

Viral Immunology and Immunopathalogy covers topics concerning the role of cellular and humoral immunity in viral infections, factors responsible for the persistence and recurrence of viral infections in the presence of immunity, mechanisms of viral immunopathology, and concepts in the development of vaccines. The book describes the history of viral immunology; the synthesis and properties of viral antigens; and the humoral immune response to viruses. The text also discusses the mechanisms of viral neutralization; cellular immunity; the role of inflammatory cells and effector molecules in combating viral infections; and the genetic control of resistance. The book concludes with chapters on herd immunity; viral immunopathology; and viral immunology and immunopathology. Immunologists, pathologists, virologists, and microbiologists will find the book useful.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The most concise, clinically relevant, and current review of medical microbiology and immunology Review of Medical Microbiology and Immunology is a succinct, high-yield review of the medically important aspects of microbiology and immunology. It covers both the basic and clinical aspects of bacteriology, virology, mycology, parasitology, and immunology and also discusses important infectious diseases using an organ system approach. The book emphasizes the real-world clinical application of microbiology and immunology to infectious diseases and offers a unique mix of narrative text, color images, tables and figures, Q&A, and clinical vignettes. • Content is valuable to any study objective or learning style • Essential for USMLE review and medical microbiology coursework • 650 USMLE-style practice questions test your knowledge and understanding • 50 clinical cases illustrate the importance of basic science information in clinical diagnosis • A complete USMLE-style practice exam consisting of 80 questions helps you prepare for the exam • Pearls impart important basic science information helpful in answering questions on the USMLE • Concise summaries of medically important organisms • Self-assessment questions with answers appear at the end of each chapter • Color images depict clinically important findings, such as infectious disease lesions • Gram stains of bacteria, electron micrographs of viruses, and microscopic images depict fungi, protozoa, and worms • Chapters on infectious diseases from an organ system perspective

In this book, a breakdown of the life and work of some of history's pioneers in the study of immunologists and virologists are thoroughly explored. As the world becomes more connected and bacteria become more antibiotic resistant, the importance of research within these two fields is becoming dyer. MRSA, Zika, SARS, and Ebola are just some of the recent outbreaks that have affected our communities. This opportune volume provides excellent biographical sketches for trailblazers in this area of science and will inspire readers to explore the top scientific contributors of the 21st century.

The textbook was compiled in accordance with officially approved teaching programs for microbiology, virology and immunology in all faculties of higher medical schools. Questions of general microbiology (basic methods of studying microorganisms, morphology, structure and classification of bacteria, their physiology, the influence of physical, chemical and biological factors on microorganisms, microbial genetics and biotechnology, antimicrobials and the concept of infection) and special microbiology (morphology, physiology, pathogenic properties of pathogens of many infectious diseases, modern methods of their diagnostics, specific prevention and therapy). The textbook also contains sections on virology, protozoology, mycology and helminthology, which examine the basic biological properties of the causative agents and the diseases they cause. A significant part of the textbook is devoted to questions of immunology (nonspecific resistance of the organism, the doctrine of antigens, the immune system of the body, immune response, immunity reactions, allergy and other types of immune responses, immunodiagnostics and immunocorrection, immunoprophylaxis and immunotherapy). The textbook contains sections on clinical and sanitary microbiology, examines the ecology of microorganisms, the normal microbiota of the human body and the effect of microorganisms on the fetus. Separate sections are devoted to the microbiota of the oral cavity and microbiological research in stomatological and pharmaceutical fields. The textbook is intended for students of medical universities, relevant departments of higher education of doctors, interns and microbiologists of all specialties.

An understanding of virus infection and the underlying role of the immune system in protection against these diseases is vital in today’s medical climate. Previously, only symptoms could be treated, as there were no antiviral therapies. The increasing amounts of research and the huge number of discoveries of immunologic agents and pathways has led to the opportunity to look to the basic physiology of the various disease process as never before. This book is designed to provide the clinician with a thorough and yet approachable textbook describing the relationships between immunology, virology and the disease process.