History Of Vaccine Development
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Author |
: Stanley A. Plotkin |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 352 |
Release |
: 2011-05-11 |
ISBN-10 |
: 9781441913395 |
ISBN-13 |
: 1441913394 |
Rating |
: 4/5 (95 Downloads) |
Synopsis History of Vaccine Development by : Stanley A. Plotkin
Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.
Author |
: Emily P. Wen |
Publisher |
: John Wiley & Sons |
Total Pages |
: 452 |
Release |
: 2014-10-06 |
ISBN-10 |
: 9781118870907 |
ISBN-13 |
: 1118870905 |
Rating |
: 4/5 (07 Downloads) |
Synopsis Vaccine Development and Manufacturing by : Emily P. Wen
Vaccine Manufacturing and Production is an invaluable reference on how to produce a vaccine - from beginning to end - addressing all classes of vaccines from a processing, production, and regulatory viewpoint. It will provide comprehensive information on the various fields involved in the production of vaccines, from fermentation, purification, formulation, to regulatory filing and facility designs. In recent years, there have been tremendous advances in all aspects of vaccine manufacturing. Improved technology and growth media have been developed for the production of cell culture with high cell density or fermentation. Vaccine Manufacturing and Production will serve as a reference on all aspects of vaccine production by providing an in-depth description of the available technologies for making different types of vaccines and the current thinking in facility designs and supply issues. This book will provide insight to the issues scientists face when producing a vaccine, the steps that are involved, and will serve as a reference tool regarding state-of-the-art vaccine manufacturing technologies and facility set-up. Highlights include: Comprehensive coverage of vaccine production : from a process point of view- fermentation to purification to formulation developments; from a production point of view - from facility design to manufacturing; and from a regulatory point of view - requirements from government agencies Authors from different major pharmaceutical and biotechnology companies Describes the challenges and issues involved in vaccine production and manufacturing of the different classes of vaccines, an area not covered by other books currently on the market
Author |
: Parag Kolhe |
Publisher |
: Elsevier |
Total Pages |
: 386 |
Release |
: 2021-09-08 |
ISBN-10 |
: 9780128143575 |
ISBN-13 |
: 0128143576 |
Rating |
: 4/5 (75 Downloads) |
Synopsis Practical Aspects of Vaccine Development by : Parag Kolhe
Formulation, Development and Manufacturing of Vaccines: The Practical Aspects provides an industry perspective on vaccine product development and manufacture that covers their formulation development, manufacture and delivery/in-use considerations of vaccine production. With the increasing complexity of vaccine products in development, there is a need for a comprehensive review of the current state of the industry and its challenges. While formulation scientists working in biotherapeutic development may be familiar with proteins, vaccines present unique challenges, including the wide range of vaccine components that may comprise proteins, polysaccharides, protein-polysaccharide conjugates, adjuvants, etc. and the varying stability and behavior of solution- and suspension-based systems. This book is an essential resource for formulation scientists, researchers in vaccine development throughout medical and life sciences, and advanced students. Includes formulation considerations for various vaccine types, including proteins, polysaccharides, conjugates and live vaccines Considers process development for solution, suspension and lyophilized products Explores the future potential of vaccines, including multi-component vaccines and novel delivery mechanisms/devices
Author |
: Andrew W. Artenstein |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 403 |
Release |
: 2009-12-11 |
ISBN-10 |
: 9781441911087 |
ISBN-13 |
: 1441911081 |
Rating |
: 4/5 (87 Downloads) |
Synopsis Vaccines: A Biography by : Andrew W. Artenstein
Why another book about vaccines? There are already a few extremely well-written medical textbooks that provide comprehensive, state-of-the-art technical reviews regarding vaccine science. Additionally, in the past decade alone, a number of engrossing, provocative books have been published on various related issues ra- ing from vaccines against specific diseases to vaccine safety and policy. Yet there remains a significant gap in the literature – the history of vaccines. Vaccines: A Biography seeks to fill a void in the extant literature by focusing on the history of vaccines and in so doing, recounts the social, cultural, and scientific history of vaccines; it places them within their natural, historical context. The book traces the lineage – the “biography” – of individual vaccines, originating with deeply rooted medical problems and evolving to an eventual conclusion. Nonetheless, these are not “biographies” in the traditional sense; they do not trace an individual’s growth and development. Instead, they follow an idea as it is conceived and dev- oped, through the contributions of many. These are epic stories of discovery, of risk-takers, of individuals advancing medical science, in the words of the famous physical scientist Isaac Newton, “by standing on the shoulders of giants. ” One grant reviewer described the book’s concept as “triumphalist”; although meant as an indictment, this is only partially inaccurate.
Author |
: Arthur Allen |
Publisher |
: W. W. Norton & Company |
Total Pages |
: 542 |
Release |
: 2008-05-17 |
ISBN-10 |
: 9781324036357 |
ISBN-13 |
: 1324036354 |
Rating |
: 4/5 (57 Downloads) |
Synopsis Vaccine: The Controversial Story of Medicine's Greatest Lifesaver by : Arthur Allen
"A timely, fair-minded and crisply written account."—New York Times Book Review Vaccine juxtaposes the stories of brilliant scientists with the industry's struggle to produce safe, effective, and profitable vaccines. It focuses on the role of military and medical authority in the introduction of vaccines and looks at why some parents have resisted this authority. Political and social intrigue have often accompanied vaccination—from the divisive introduction of smallpox inoculation in colonial Boston to the 9,000 lawsuits recently filed by parents convinced that vaccines caused their children's autism. With narrative grace and investigative journalism, Arthur Allen reveals a history illuminated by hope and shrouded by controversy, and he sheds new light on changing notions of health, risk, and the common good.
Author |
: Michael Kinch |
Publisher |
: Simon and Schuster |
Total Pages |
: 486 |
Release |
: 2018-07-03 |
ISBN-10 |
: 9781681778204 |
ISBN-13 |
: 1681778203 |
Rating |
: 4/5 (04 Downloads) |
Synopsis Between Hope and Fear by : Michael Kinch
If you have a child in school, you may have heard stories of long-dormant diseases suddenly reappearing—cases of measles, mumps, rubella, and whooping cough cropping up everywhere from elementary schools to Ivy League universities because a select group of parents refuse to vaccinate their children. Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent—and could easily be undone. In the tradition of John Barry’s The Great Influenza and Siddhartha Mukherjee’s The Emperor of All Maladies, Between Hope and Fear relates the remarkable intersection of science, technology, and disease that has helped eradicate many of the deadliest plagues known to man.
Author |
: John Rhodes |
Publisher |
: University of Chicago Press |
Total Pages |
: 185 |
Release |
: 2021-04-12 |
ISBN-10 |
: 9780226792514 |
ISBN-13 |
: 022679251X |
Rating |
: 4/5 (14 Downloads) |
Synopsis How to Make a Vaccine by : John Rhodes
Understand the Virus -- Explore the Immune System -- Discover a Vaccine -- Develop Vaccines -- Evaluate the Contenders -- Don't Count on the Magic Bullet -- Overcome the Hurdles -- Embrace Many Solutions.
Author |
: Paul A. Offit |
Publisher |
: Yale University Press |
Total Pages |
: 260 |
Release |
: 2007-09-18 |
ISBN-10 |
: 0300126050 |
ISBN-13 |
: 9780300126051 |
Rating |
: 4/5 (50 Downloads) |
Synopsis The Cutter Incident by : Paul A. Offit
Vaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, thathas led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases.
Author |
: Paul A. Offit, M.D. |
Publisher |
: HarperCollins |
Total Pages |
: 323 |
Release |
: 2022-02-01 |
ISBN-10 |
: 9780063251762 |
ISBN-13 |
: 0063251760 |
Rating |
: 4/5 (62 Downloads) |
Synopsis Vaccinated by : Paul A. Offit, M.D.
Vaccines save millions of lives every year, and one man, Maurice Hilleman, was responsible for nine of the big fourteen. Paul Offit recounts his story and the story of vaccines Maurice Hilleman discovered nine vaccines that practically every child gets, rendering formerly dread diseases—including often devastating ones such as mumps and rubella—practically forgotten. Paul A. Offit, a vaccine researcher himself, befriended Hilleman and, during the great man’s last months, interviewed him extensively about his life and career. Offit makes an eloquent and compelling case for Hilleman’s importance, arguing that, like Jonas Salk, his name should be known to everyone. But Vaccinated is also enriched and enlivened by a look at vaccines in the context of modern medical science and history, ranging across the globe and throughout time to take in a fascinating cast of hundreds, providing a vital contribution to the continuing debate over the value of vaccines.
Author |
: Anthony R. Rees |
Publisher |
: Academic Press |
Total Pages |
: 516 |
Release |
: 2022-01-04 |
ISBN-10 |
: 9780128127551 |
ISBN-13 |
: 0128127554 |
Rating |
: 4/5 (51 Downloads) |
Synopsis A New History of Vaccines for Infectious Diseases by : Anthony R. Rees
A New History of Vaccines for Infectious Diseases: Immunization - Chance and Necessity covers the developments of vaccines and how they have obliterated many fatal diseases and infections over time. The book treads a neutral path but does not avoid discussion. As uncertainty in the outcome of vaccination can only be determined by experiment, the path to vaccine development has been scientifically complex because the immune system and the manner in which humans respond to infection is variable and complex. Finally, the book describes the risks and benefits of vaccines in a visibly objective manner. - 2023 PROSE Awards - Winner: Finalist: History of Science, Medicine, and Technology: Association of American Publishers - Gives an objective description of the science behind vaccine discovery - Presents awareness and discussions on controversies, both past and present - Provides historical context to the scientific aspects of immunization, including what worked, what didn't, and why - Written by a scientist with no 'vested interest' in vaccine development - Clears up many misunderstandings for today's vaccination policies