Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, the Handbook of Heterocyclic Chemistry is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. Contains more than 1500 clearly drawn structures and reactions. The highly systematic coverage given to the subject makes this one of the most authoritative single-volume accounts of modern heterocyclic chemistry available and should be useful reference for those teaching a heterocyclic course. - Covers the structure, reactivity and synthesis of all heterocyclic compounds as distilled from the larger 15-volume reference work - Saves researchers time when they require important information on heterocycles--speeding them to thousands of clearly drawn chemical structures and pertinent reviews by leading experts - Features 35% new material to compliment the completely revised text

Provides a one-volume overall picture of the largest of the classical divisions of organic chemistry, suitable for the graduate or advanced undergraduate student, as well as for research workers, both specialists in the field and those engaged in another discipline and requiring knowledge of heterocyclic chemistry. It represents Volume 9 of Comprehensive Heterocyclic Chemistry and utilizes the general chapters which appear in the 8-volume work. The highly systematic coverage given to the subject makes this the most authoritative one-volume account of modern heterocyclic chemistry available.

Heterocyclic chemistry is the largest of the classical divisions of organic chemistry. Heterocyclic compounds are widely distributed in Nature, playing a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. The range of known compounds is enormous, encompassing the whole spectrum of physical, chemical and biological properties. This book provides a balanced, a concise and informative account of heterocyclic chemistry that will be suitable for graduate or advanced undergraduate students and a convenient reference book for research workers, for both specialists int he field and those whose expertise lies in other areas but who nevertheless need information on heterocylic chemistry. The Handbook of Heterocyclic Chemistry is illustrated throughout with thousands of clearly drawn chemical structures. The highly systematic coverage given to the subject makes this the most authoritative one-volume account of modern heterocyclic chemistry available. * Provides a balanced, concise and informative account of heterocyclic chemistry * Written by leading scholars and industry experts * Illustrated throughout with thousands of clearly drawn chemical structures * The most authoritative one-volume account of modern heterocyclic chemistry available

This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.

Heterocyclic compounds are important natural products and have widespread uses as pharmaceuticals, dyestuffs, agrochemicals, and pigments. This textbook provides a survey of the various types of heterocyclic ring system. The text has been organized in such a way that the general aspects of the chemistry and properties of heterocyclic compounds are described in the first half of the book and specific classes of heterocycles are then discussed in the second half. Both aromatic and nonaromatic ring systems are included. various methods available for synthesising heterocyclic compounds. This chapter has been expanded and brought up to date in the Second Edition. The second half of the book has been re-organized so that the most common aromatic heterocyclic ring systems are introduced first. Modern applications of heterocyclic chemistry in medicine and in organic synthesis are given prominence in this part of the text. The final chapter provides a guide to the current methods of naming heterocyclic compounds. text, and by a set of problems. Throughout the text numerous references are given to socialist reviews and, where appropriate, to papers from the primary literature. chemistry and for students of biochemistry, pharmacology and related subjects who have a good background knowledge of organic chemistry. It should also be useful as a reference source to more advanced workers in these subjects.

Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.

This advanced text-cum-reference book presents a comprehensive account of the syntheses, reactions, properties and applications of all the most significant classes of heterocyclic compounds. This second volume in the series is an essential tool not only for advanced undergraduates and graduates, but also for academic and industrial researchers in organic, medicinal, pharmaceutical, dye and agricultural chemistry.

Heterocyclic chemistry is an expanding subject, thanks to the research currently being done in the field. Heterocyclic components have many diverse applications in pharmacy, medicine, agriculture and other life sciences, so there is a constant need for updated information. This fourth edition retains many of the features that have proved successful in prior editions. It consists of 11 comprehensive chapters which discuss the heterocyclic components ring by ring with an emphasis on the stereochemistry of reactions and their mechanisms. Each chapter is very well referenced, with a thoroughly updated bibliography and contains a set of self assessment problems at the end for the reader to answer. The book is intended for use as a textbook on courses in heterocyclic chemistry, but it is also relevant to biochemistry, pharmacy and medicine, and will be a valuable addition to any medical or life science library.