A drug is typically manufactured through chemical synthesis, which means that it is made by combining specific chemical ingredients in an ordered process. Biologics are medicines made from living cells through highly complex manufacturing processes and must be handled and administered under carefully monitored conditions. Biologics are used to prevent, treat, diagnose, or cure a variety of diseases including cancer, chronic kidney disease, autoimmune disorders, and infectious diseases. A biosimilar is a biologic that is similar to another biologic drug already that has already been approved. This book is a complete guide to the use of biologics and biosimilars in the treatment of dermatologic disorders. Beginning with an overview of the history and classification of biologics and the concept of biosimilars, the following chapters explain their therapeutic use for different skin conditions. The final sections cover related topics such as cost effectiveness and quality of life with biologic therapy, and the book concludes with discussion on future developments and the use of small molecule treatment. Key points Complete guide to use of biologics and biosimilars in treatment of dermatologic disorders Covers many different skin diseases and conditions Discusses related topics such as cost effectiveness and quality of life Covers future development of small molecule therapy

A comprehensive primer and reference, this book provides pharmacists and health practitioners the relevant science and policy concepts behind biologics, biosimilars, and biobetters from a practical and clinical perspective. Explains what pharmacists need to discuss the equivalence, efficacy, safety, and risks of biosimilars with physicians, health practitioners, and patients about Guides regulators on pragmatic approaches to dealing with these drugs in the context of rapidly evolving scientific and clinical evidence Balances scientific information on complex drugs with practical information, such as a checklist for pharmacists

Nail disorders are a specialized group of disorders which are often neglected during post graduate teaching. This book aims to provide a comprehensive review covering the diagnostic and therapeutic aspects of nail disorders. It discusses the basics of nail unit, common conditions like infections, tumors and genetic diseases, diagnostic armamentarium involved in nail diseases like KOH mount, onychoscopy, imaging and surgical management of nail diseases which includes anesthesia of nail unit, nail biopsy and advanced nail procedures including video demonstration of such procedures. This book elaborates on nails in systemic diseases and briefly covers nail cosmetics and nail photography. Key Features Comprehensively reviews nail disorders Includes diagnosis, therapeutic and surgical aspect Discusses Onychoscopy Reviews the importance of nail photography

Practical and highly illustrated, Genital Dermatology Manual, 4th Edition, by Drs. Libby Edwards and Peter J. Lynch, helps clinicians at all levels of experience arrive at an accurate diagnosis for both common and rare genital dermatologic lesions. More than 500 full-color photographs are arranged by appearance for rapid identification, offering superb visual guidance even for conditions not previously encountered. This easy-to-use reference is ideal for any clinician who sees men and women with disorders of the external genitalia, including dermatologists, gynecologists, urologists, primary care physicians, nurse practitioners, nurse midwives, and physician assistants.

As the generic pharmaceutical industry continues to grow and thrive, so does the need to conduct adequate, efficient bioequivalence studies. In recent years, there have been significant changes to the statistical models for evaluating bioequivalence. In addition, advances in the analytical technology used to detect drug and metabolite levels have m

Dermoscopy is a non-invasive, widely used diagnostic tool that aids the diagnosis of skin lesions and is proven to increase the accuracy of melanoma diagnosis. This book is a practical, self-assessment guide to the diagnosis of skin disorders by dermoscopy. Beginning with an introduction to the technique, the following sections describe its use for different skin conditions, including pigmentation disorders, infectious diseases, skin tumours, and more. The final sections cover onychoscopy (nails) and trichoscopy (hair and scalp). Each case is highly illustrated with clinical photographs and diagrams, and includes a summary of the key features of the topic and dermoscopic clinical pearls. Key Points Practical, self-assessment guide to diagnosis of skin disorders by dermoscopy Covers numerous different skin conditions Includes sections on onychoscopy and trichoscopy Highly illustrated with clinical photographs and diagrams

This extensively revised second edition provides an up-to-date and highly informative textbook on psoriasis. The understanding of the mechanisms behind the disease and the available treatment options have continued to develop rapidly in recent times, with this vital resource covering the latest in these management options, including targeted T-cell therapy, the use of immunomodulators, systemic therapies, and ultraviolet and laser therapy. In addition, it provides a detailed overview of the pathophysiology, comorbidities, epidemiology and triggers of the disease. Advances in Psoriasis: A Multisystemic Guide extensively details the scientific basis and practice management of psoriasis. It is therefore a vital resource for practicing and trainee dermatologists looking to develop their clinical knowledge of how to manage and treat these patients.

This book is a complete guide to dermatologic surgery for clinicians. Divided into 52 sections, the text begins with an overview of surgical instruments, local anaesthesia, sutures, dressings and skin biopsy. The following chapters cover numerous techniques for different dermatologic conditions, from mole surgery, vitiligo, and nail surgery, to Mohs surgery, laser scar revision, fillers, and much more. Each procedure is described with a step by step approach and includes tips and tricks, modifications, potential complications and recent advances. Both common and more complex disorders and techniques are explained in detail. The comprehensive text is further enhanced by more than 1800 clinical and surgical photographs, diagrams and tables. Key points Comprehensive guide to dermatologic surgery Covers numerous common and more complex disorders and techniques Tips and tricks, modifications, complications and recent advances highlighted for each topic Highly illustrated with more than 1800 photographs, diagrams and tables

This is a thoroughly revised, updated and rewritten edition of the book reflecting guidelines and studies till early 2020. It contains original Jopling’s clinical text which has been updated with over 370 images and diagrams. It will serve as a textbook for postgraduate students in dermatology as well as a ready-reckoner for all health personnel dealing with leprosy at various levels.

This book is a practical guide to the diagnosis of dermatologic disorders. Each section presents clinical cases, followed by questions and answers, then an explanation of the clinical diagnosis and further investigations. The text covers numerous different skin disorders, both common and rare, and details recent advances in the field. Topics are presented with an algorithmic approach to assist trainees in preparation for exams. The comprehensive text is highly illustrated by clinical photographs and tables to enhance learning. Key Points Practical guide to diagnosis of dermatologic disorders Presents clinical cases, questions and answers, clinical diagnosis and further investigations Includes recent advances in the field Algorithmic approach assists trainees with exam preparation