Hair in Toxicology: An Important Biomonitor is the first book of its kind devoted exclusively to in-depth analysis of the hair shaft as an important tool for a diverse range of scientific investigations. This authoritative book combines contributions from experts in academic, governmental and industrial environments, to provide a unique, comprehensive look at: - Why hair can serve as an invaluable bio-resource in toxicology, with up-to-date reviews on hair growth, hair fibre formation and hair pigmentation - Information (including regulatory details) on the exposure of hair (and by extension the body) to drug and non-drug chemicals and pollutants - Toxicological issues relevant to the use of hair products (including colourants, shampoos and depilatories) - The ability of hair to capture information on personal identity, chemical exposure, and environmental interactions - How hair can provide an understanding of human life from archaeological and historical perspectives - Future direction in the use of hair in toxicology Hair in Toxicology: An Important Biomonitor is ideal as a reference and guide to investigations in the biomedical, biochemical and pharmaceutical sciences at the graduate and post graduate level.

Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair. - Unites an international team of leading experts to provide an update on the cutting-edge advances in the toxicological analysis of hair - Demonstrates toxicological techniques relating to a variety of scenarios and exposure types - Ideal resource for the further study of the psychoactive substances, drug-facilitated crimes, ecotoxicology, analytical toxicology, occupational toxicology, toxicity testing, and forensic toxicology - Includes detailed instructions for the collection, preparation, and handling of hair, and how to best interpret results

Many advances have been made since the publication of Drug Testing in Hair. The mid-1990s witnessed the progress in cannabis detection while the late 1990s focused on benzodiazepines detection and the applications in doping control. In more recent years, toxicologists centered on the detection in hair of a single exposure and the related applicatio

Toxicological Aspects of Drug-Facilitated Crimes provides readers with an overview of the field of DFC: its history, toxicological effects, analysis, interpretation of results, the roles that age, gender and race may play, and clinical presentations of these drugs. The most commonly used drugs in DFC are addressed (alcohol, cannabis, MDMA, and cocaine), as well as an emerging range of pharmaceuticals (benzodiazepines, hypnotics, sedatives, neuroleptics, histamine H1-antagonists, or anesthetics), which are becoming more widely used, but are more difficult to detect. Edited by a world-renowned expert in the field of Forensic and Analytical Toxicology, Pascal Kintz, this book investigates toxicants of emerging concern and brings together a number of experts in the field to address the most recent discoveries on DFC toxicology. - Brings together the latest research on the toxicological analysis of drug-facilitated crimes (DFC), with real-life case studies - Provides up-to-date analytical techniques for determining toxicity levels in blood, urine, and hair - Covers all types of toxicants involved in DFC, including alcohol, cannabis, MDMA, and a wide variety of pharmaceuticals

Human hair is the subject of a wide range of scientific investigations. Its chemical and physical properties are of importance to the cosmetics industry, forensic scientists, and to biomedical researchers. This updated and enlarged fourth edition continues the tradition of its predecessor as being the definitive monograph on the subject. It now contains new information on various topics including: chemical hair damage, the cause of dandruff, skin and eye irritation, hair straightening, and others. Chemical and Physical Behavior of Human Hair is a teaching guide and reference volume for cosmetic chemists and other scientists in the hair products industry, academic researchers studying hair and hair growth, textile scientists, and forensic specialists.

Mercury is widespread in our environment. Methylmercury, one organic form of mercury, can accumulate up the aquatic food chain and lead to high concentrations in predatory fish. When consumed by humans, contaminated fish represent a public health risk. Combustion processes, especially coal-fired power plants, are major sources of mercury contamination in the environment. The U.S. Environmental Protection Agency (EPA) is considering regulating mercury emissions from those plants. Toxicological Effects of Methylmercury reviews the health effects of methylmercury and discusses the estimation of mercury exposure from measured biomarkers, how differences between individuals affect mercury toxicity, and appropriate statistical methods for analysis of the data and thoroughly compares the epidemiological studies available on methylmercury. Included are discussions of current mercury levels on public health and a delineation of the scientific aspects and policy decisions involved in the regulation of mercury. This report is a valuable resource for individuals interested in the public health effects and regulation of mercury. The report also provides an excellent example of the implications of decisions in the risk assessment process for a larger audience.

A comprehensive review of the science of drug testing in all its aspects, placing emphasis on technologies that use body fluids other than urine for determining the presence of drugs of abuse. The authors discuss the various body fluid specimens suitable for testing for illicit drugs-particularly saliva, sweat, and hair-describe the structural and manufacturing aspects of on-site testing devices based on lateral flow immunoassay, and detail the pitfalls of using these specimens. They also discuss in detail the problem of sample adulteration and its detection. Since oral fluid has the best potential of succeeding urine as the next matrix of choice for drug detection, four popular saliva testing devices are examined: Intercept®, the Drager Drug Test®, Oratect®, and Drugwipe. Political, social, and legal issues are also considered in articles on privacy, the use of drug testing in courts, and the problem of sample adulteration.

Hair is the subject of this book, including the anatomy of the hair follicle, developmental stages, analyzed by light and electron microscopy, hair ultrastructure, nerve and blood supply, specialized hairs and hair organs, and a review of the present techniques to cultivate hair follicle cells in vitro. In the clinical part several chapters describe the most important diseases and possibilities for treatment. Hair care products and their toxicology are the subject of further sections. Extensive reviews of the antiandrogens, a most important group of drugs influencing hair growth, and of their clinical use in conditions such as androgenetic alopecias and hirsutism are included as well. Finally, surgical techniques for hair transplantation are discussed. This book is a standard textbook for everything pertaining to hair under normal and pathological conditions.

Covering a wide range of research currently being done in drug analysis, Drug Testing Technology: Assessment of Field Applications compares and evaluates various methods used to determine abused drugs taken by individuals, and their application in various programs and contexts. Controversies associated with various methods, including urine analysis and hair analysis, are examined. Contributors from a wide diversity of disciplines offer advanced knowledge, encompassing work which is technical as well as markedly philosophical. Chapters provide overviews of drug incorporation into hair; the use of hair analysis for compliance measurement in the use of anti-epileptic medications; and the application of drug testing to the psychiatric treatment of substance abuse disorders. Drug Testing Technology: Assessment of Field Applications provides information useful in medical applications, workplace testing, criminal justice monitoring community epidemiology, and drug treatment assessment.