Goodman's Medical Cell Biology, Fourth Edition, has been student tested and approved for decades. This updated edition of this essential textbook provides a concise focus on eukaryotic cell biology (with a discussion of the microbiome) as it relates to human and animal disease. This is accomplished by explaining general cell biology principles in the context of organ systems and disease.This new edition is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study. - Includes five new chapters: Mitochondria and Disease, The Cell Biology of the Immune System, Stem Cells and Regenerative Medicine, Omics, Informatics, and Personalized Medicine, and The Microbiome and Disease - Contains over 150 new illustrations, along with revised and updated illustrations - Maintains the same vision as the prior editions, teaching cell biology in a medically relevant manner in a concise, focused textbook

Medical Cell Biology, Third Edition, focuses on the scientific aspects of cell biology important to medical students, dental students, veterinary students, and prehealth undergraduates. With its National Board-type questions, this book is specifically designed to prepare students for this exam. The book maintains a concise focus on eukaryotic cell biology as it relates to human and animal disease, all within a manageable 300-page format. This is accomplished by explaining general cell biology principles in the context of organ systems and disease. This updated version contains 60% new material and all new clinical cases. New topics include apoptosis and cell death from a neural perspective; signal transduction as it relates to normal and abnormal heart function; and cell cycle and cell division related to cancer biology. - 60% New Material! - New Topics include: - Apoptosis and cell dealth from a neural perspective - Signal transduction as it relates to normal and abnormal heart function - Cell cycle and cell division related to cancer biology - All new clinical cases - Serves as a prep guide to the National Medical Board Exam with sample board-style questions (using Exam Master(R) technology): www.exammaster.com - Focuses on eukaryotic cell biology as it related to human disease, thus making the subject more accessible to pre-med and pre-health students

Goodman's Basic Medical Endocrinology, Fifth Edition, has been student tested and approved for decades. This essential textbook provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. It is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study. - Clinical case studies in every chapter - E-book version available with every copy for obtaining images and tables for lectures or notes - Clinicians added as co-authors to enhance usefulness by physicians and medical students and residents - Detailed molecular biology of hormones and hormone action for graduate and advanced undergraduate students - Expanded and updated color images emphasizing hormone action at the molecular level - In-depth molecular biology and clinical sections boxed for ease of access

A complete one-stop review of the clinically important aspects of histology and cell biology--user-friendly, concise, and packed with learning aids! The ideal review for course exams and the USMLE! This popular title in the LANGE series is specifically designed to help you make the most of your study time--whether you're studying histology and cell biology for the first time or reviewing for course exams or the USMLE. With this focused review you will be able to pinpoint your weak areas, and then improve your comprehension with learning aids especially designed to help you understand and retain even the most difficult material. You will find complete easy-to-follow coverage of all the need-to-know material: fundamental concepts, the four basic tissues types, and organs and organ systems--presented in a consistent, time-saving design. At the conclusion of the book, you will find a Diagnostic Final Exam that has been updated with longer, case-related stems that mimic the USMLE Step 1 examination. Each chapter is devoted to one specific topic and includes learning aids such as: Objectives that point out significant facts and concepts that you must know about each topic Max Yield(tm) study questions that direct you to key facts needed to master material most often covered on exams A synopsis presented in outline form that reviews all the basic histology and related cell biology covered on exams Multiple-choice questions written in a style most commonly used in medical school NEW to this Edition: Thoroughly revised Q&A Completely updated text and practice questions to reflect current knowledge Information added to each chapter regarding relevant pathology/clinical issues; possibly as a separate colored box Visit www.LangeTextbooks.com to access valuable resources and study aids. Thorough coverage you won't find anywhere else! FUNDAMENTAL CONCEPTS: Methods of Study, The Plasma Membrane & Cytoplasm, The Nucleus & Cell Cycle, THE FOUR BASIC TISSUE TYPES: Epithelial Tissue, Connective Tissue, Adipose Tissue, Cartilage, Bone, Integrative Multiple-Choice Questions: Connective Tissues Nerve Tissue, Muscle Tissue, Integrative Multiple-Choice Questions: Basic Tissue Types, ORGANS & ORGAN SYSTEMS: Circulatory System, Peripheral Blood, Hematopoiesis, Lymphoid System, Digestive Tract, Glands Associated with the Digestive Tract, Integrative Multiple-Choice Questions: Digestive System, Respiratory System, Skin, Urinary System, Pituitary & Hypothalamus, Adrenals, Islets of Langerhans, Thyroid, Parathyroids, & Pineal Body, Male Reproductive System, Female Reproductive System, Integrative Multiple-Choice Questions: Endocrine System, Sense Organs, Diagnostic Final Examination

Hormesis is a poorly understood phenomenon affecting all forms of life on earth. This groundbreaking book summarizes and analyzes the various positives of hormesis in an attempt to reveal hormesis as a fundamental principle of biomedical sciences as a whole.

Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts Explores endocrine cells biology in normal and pathologic conditions Covers new aspects of endocrine cell function in distinct tissues Provides a view into the biological effect in local and systemic levels 15 new chapters covering the recent developments in the field

Viruses interact with host cells in ways that uniquely reveal a great deal about general aspects of molecular and cellular structure and function. Molecular and Cellular Biology of Viruses leads students on an exploration of viruses by supporting engaging and interactive learning. All the major classes of viruses are covered, with separate chapters for their replication and expression strategies, and chapters for mechanisms such as attachment that are independent of the virus genome type. Specific cases drawn from primary literature foster student engagement. End-of-chapter questions focus on analysis and interpretation with answers being given at the back of the book. Examples come from the most-studied and medically important viruses such as HIV, influenza, and poliovirus. Plant viruses and bacteriophages are also included. There are chapters on the overall effect of viral infection on the host cell. Coverage of the immune system is focused on the interplay between host defenses and viruses, with a separate chapter on medical applications such as anti-viral drugs and vaccine development. The final chapter is on virus diversity and evolution, incorporating contemporary insights from metagenomic research. Key selling feature: Readable but rigorous coverage of the molecular and cellular biology of viruses Molecular mechanisms of all major groups, including plant viruses and bacteriophages, illustrated by example Host-pathogen interactions at the cellular and molecular level emphasized throughout Medical implications and consequences included Quality illustrations available to instructors Extensive questions and answers for each chapter

Balances coverage of the concepts of cell and molecular biology, using examples of experimentation to support those concepts. As experimental techniques become more diverse and complex, it is increasingly necessary to identify individual studies that have a broad impact on our understanding of cell biology. This text describes in detail some of the key experimental findings, along with the original data and figures.

This Second Edition of the highly praised Cell Biology: A Laboratory Handbook brings together 260 new and revised chapters. Each chapter is concisely written and beautifully illustrated, making this attractive four-volume set a worthwhile addition to any desktop, and the up-to-date instructions for biological techniques make this reference the next best thing to having the expert at your side. Dr. Julio Celis and the Associate Editors have drawn on peer review from the scientific community to include 40 percent new material in this much-needed and updated laboratory manual. In one easy to use reference, current and classic protocols are presented in a clear and reader-friendly format that makes this manual a necessity to undergraduate and graduate students as well as technicians and instructors. Features: * Contains more than 40% new material * Provides cell biologists and other life scientists with the most up-to-date instructions for basic and advanced cell biological techniques, including those at the interface between cell and molecular biology * Features uniform style and editing and includes contributions from world-renowned authorities in their respective fields * Contains i

Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies. Ion Channels and Disease provides an informative and up-to-date account of our present understanding of ion channels and the molecular basis of ion channel diseases. It includes a basic introduction to the relevant aspects of molecular biology and biophysics and a brief description of the principal methods used to study channelopathies. For each channel, the relationship between its molecular structure and its functional properties is discussed and ways in which genetic mutations produce the disease phenotype are considered. This book is intended for research workers and clinicians, as well as graduates and advanced undergraduates. The text is clear and lively and assumes little knowledge, yet it takes the reader to frontiers of what is currently known about this most exciting and medically important area of physiology. - Introduces the relevant aspects of molecular biology and biophysics - Describes the principal methods used to study channelopathies - Considers single classes of ion channels with summaries of the physiological role, subunit composition, molecular structure and chromosomal location, plus the relationship between channel structure and function - Looks at those diseases associated with defective channel structures and regulation, including mutations affecting channel function and to what extent this change in channel function can account for the clinical phenotype