Highly pathogenic avian influenza (HPAI) is a severe and highly contagious disease that has severe impacts on animal and human health, livelihoods, and the economy. At the time of the consultation, the recent panzootic had affected more than 70 countries and territories, resulting in over 11 000 disease events in both wild and domestic bird populations. The disease has also spilled over to several mammalian species, including humans, and may result in severe ecological and biodiversity consequences. Considering the alarming spread of HPAI and the evolution of avian influenza in wild birds, The Food and Agricultural Organization (FAO) and Network of Expertise on Animal Influenza (OFFLU) brought together the global scientific community to review the latest science and evidence on the disease, to support development/implementation of disease prevention and control strategies and policies and contribute to global efforts towards reducing pandemic risk. The report summarizes the meeting discussions, and key recommendations to reduce the transmission of HPAI along the poultry value chains, and the spillover risk to humans and wildlife. The meeting report will contribute to revising the FAO-WOAH global control strategy for HPAI and developing evidence-based policies and research agendas to tackle the disease. Sharing the meeting report with technical experts and policy makers will help support the development of a research and development agenda to tackle HPAI globally.

Since then, most affected countries have eliminated the disease.

Some avian influenza viruses can infect humans, cause disease, and even result in deaths. This book comprehensively and systematically presents the theory, diagnosis and clinical treatment of typical avian influenza viruses in human. The first chapters introduce the ethiology, epidemiology, clinical diagnosis and treatment of human avian influenza and complications. The following chapters include overview, extensive images, differential diagnosis and clinical cases of H7N9, H5N1, H5N6, H10N8, H9N2 and H7N4 avian influenza. Written by practitioners directly involved in the prevention and clinical treatment of human avian influenza, it will be an invaluable aid for practitioners in centers for infectious disease control and prevention, hospitals, and academic institutions to improve prevention, diagnosis and treatment of avian influenza in human.

When, in late 2011, it became public knowledge that two research groups had submitted for publication manuscripts that reported on their work on mammalian transmissibility of a lethal H5N1 avian influenza strain, the information caused an international debate about the appropriateness and communication of the researchers' work, the risks associated with the work, partial or complete censorship of scientific publications, and dual-use research of concern in general. Recognizing that the H5N1 research is only the most recent scientific activity subject to widespread attention due to safety and security concerns, on May 1, 2012, the National Research Council's Committee on Science, Technology and Law, in conjunction with the Board on Life Sciences and the Institute of Medicine's Forum on Microbial Threats, convened a one-day public workshop for the purposes of 1) discussing the H5N1 controversy; 2) considering responses by the National Institute of Allergy and Infectious Diseases (NIAID), which had funded this research, the World Health Organization, the U.S. National Science Advisory Board for Biosecurity (NSABB), scientific publishers, and members of the international research community; and 3) providing a forum wherein the concerns and interests of the broader community of stakeholders, including policy makers, biosafety and biosecurity experts, non-governmental organizations, international organizations, and the general public might be articulated. Perspectives on Research with H5N1 Avian Influenza: Scientific Enquiry, Communication, Controversy summarizes the proceedings of the workshop.

With the growing global fear of a major pandemic, avian influenza (AI) virus research has greatly increased in importance. In Avian Influenza Virus, an expert team of researchers and diagnosticians examine the fundamental, yet essential, virological methods for AI virus research and diagnostics as well as some of the newest molecular procedures currently used for basic and applied research. They present exciting, cutting-edge new methods that focus both on studying the virus itself and on work with avian hosts, an area greatly lacking in research.

In March and early April 2009, a new, swine-origin 2009-H1N1 influenza A virus emerged in Mexico and the United States. During the first few weeks of surveillance, the virus spread by human-to-human transmission worldwide to over 30 countries. On June 11, 2009, the World Health Organization (WHO) raised the worldwide pandemic alert level to Phase 6 in response to the ongoing global spread of the novel influenza A (H1N1) virus. By October 30, 2009, the H1N1 influenza A had spread to 191 countries and resulted in 5,700 fatalities. A national emergency was declared in the United States and the swine flu joined SARS and the avian flu as pandemics of the 21st century. Vaccination is currently available, but in limited supply, and with a 60 percent effectiveness rate against the virus. The story of how this new influenza virus spread out of Mexico to other parts of North America and then on to Europe, the Far East, and now Australia and the Pacific Rim countries has its origins in the global interconnectedness of travel, trade, and tourism. Given the rapid spread of the virus, the international scientific, public health, security, and policy communities had to mobilize quickly to characterize this unique virus and address its potential effects. The World Health Organization and Centers for Disease Control have played critical roles in the surveillance, detection and responses to the H1N1 virus. The Domestic and International Impacts of the 2009-H1N1 Influenza A Pandemic: Global Challenges, Global Solutions aimed to examine the evolutionary origins of the H1N1 virus and evaluate its potential public health and socioeconomic consequences, while monitoring and mitigating the impact of a fast-moving pandemic. The rapporteurs for this workshop reported on the need for increased and geographically robust global influenza vaccine production capacities; enhanced and sustained interpandemic demand for seasonal influenza vaccines; clear "triggers" for pandemic alert levels; and accelerated research collaboration on new vaccine manufacturing techniques. This book will be an essential guide for healthcare professionals, policymakers, drug manufacturers and investigators.

H1N1 ("swine flu"), SARS, mad cow disease, and HIV/AIDS are a few examples of zoonotic diseases-diseases transmitted between humans and animals. Zoonotic diseases are a growing concern given multiple factors: their often novel and unpredictable nature, their ability to emerge anywhere and spread rapidly around the globe, and their major economic toll on several disparate industries. Infectious disease surveillance systems are used to detect this threat to human and animal health. By systematically collecting data on the occurrence of infectious diseases in humans and animals, investigators can track the spread of disease and provide an early warning to human and animal health officials, nationally and internationally, for follow-up and response. Unfortunately, and for many reasons, current disease surveillance has been ineffective or untimely in alerting officials to emerging zoonotic diseases. Sustaining Global Surveillance and Response to Emerging Zoonotic Diseases assesses some of the disease surveillance systems around the world, and recommends ways to improve early detection and response. The book presents solutions for improved coordination between human and animal health sectors, and among governments and international organizations. Parties seeking to improve the detection and response to zoonotic diseases-including U.S. government and international health policy makers, researchers, epidemiologists, human health clinicians, and veterinarians-can use this book to help curtail the threat zoonotic diseases pose to economies, societies, and health.

"This document represents the results of a stocktaking exercise initiated by ECTAD-RAP in Bangkok in January 2012 and consolidated at the 6th Annual Regional ECTAD Meeting (AREM). ECTAD-RAP also coordinated the different stages of data gathering, compilation, feedback and collation of the results, as well as the design and development of display materials and the production of this handbook"--Page xiii.

This book reviews the medical history of Hong Kong, beginning with its birth as a British colony. It introduces the origins of Hong Kong’s medical education, which began in 1887 when the London Missionary Society set up the Hong Kong College of Medicine for Chinese. When the University of Hong Kong was established in 1911, the College became its medical faculty. The faculty has gained distinction over the years for innovative surgical techniques, for discovering the SARS virus and for its contribution to advances in medical and health sciences. This book is meant for general readers as well as medical practitioners. It is a work for anyone interested in Hong Kong or in medical education.

Avian Influenza poses a looming threat for human and animal health. The old paradigm was that the disease in waterfowl, poultry, pigs and man was caused by separate viruses that stayed within their own niche. Deadly outbreaks have shattered this view. This timely reference examines such sensitive issues as regulation of low pathogenic and high pathogenic AI, surveillance of waterfowl, live bird markets, and outbreak control in densely populated areas.