In the quest to understand and model the healthy or sick human body, re searchers and medical doctors are utilizing more and more quantitative tools and techniques. This trend is pushing the envelope of a new field we call Biomedical Computing, as an exciting frontier among signal processing, pattern recognition, optimization, nonlinear dynamics, computer science and biology, chemistry and medicine. A conference on Biocomputing was held during February 25-27, 2001 at the University of Florida. The conference was sponsored by the Center for Applied Optimization, the Computational Neuroengineering Center, the Biomedical En gineering Program (through a Whitaker Foundation grant), the Brain Institute, the School of Engineering, and the University of Florida Research & Graduate Programs. The conference provided a forum for researchers to discuss and present new directions in Biocomputing. The well-attended three days event was highlighted by the presence of top researchers in the field who presented their work in Biocomputing. This volume contains a selective collection of ref ereed papers based on talks presented at this conference. You will find seminal contributions in genomics, global optimization, computational neuroscience, FMRI, brain dynamics, epileptic seizure prediction and cancer diagnostics. We would like to take the opportunity to thank the sponsors, the authors of the papers, the anonymous referees, and Kluwer Academic Publishers for making the conference successful and the publication of this volume possible. Panos M. Pardalos and Jose C.

PHEMT devices and their incorporation into advanced monolithic integrated circuits is the enabling technology for modern microwave/millimeter wave system applications. Although still in its infancy, PHEMT MIMIC technology is already finding applications in both military and commercial systems, including radar, communication and automotive technologies. The successful team in a globally competitive market is one in which the solid-state scientist, circuit designer, system engineer and technical manager are cognizant of those considerations and requirements that influence each other's function. This book provides the reader with a comprehensive review of PHEMT technology, including materials, fabrication and processing, device physics, CAD tools and modelling, monolithic integrated circuit technology and applications. Readers with a broad range of specialities in one or more of the areas of materials, processing, device physics, circuit design, system design and marketing will be introduced quickly to important basic concepts and techniques. The specialist who has specific PHEMT experience will benefit from the broad range of topics covered and the open discussion of practical issues. Finally, the publication offers an additional benefit, in that it presents a broad scope to both the researcher and manager, both of whom must be aware and educated to remain relevant in an ever-expanding technology base.

Following developments in modern geometry, logic and physics, many scientists and philosophers in the modern era considered Kant’s theory of intuition to be obsolete. But this only represents one side of the story concerning Kant, intuition and twentieth century science. Several prominent mathematicians and physicists were convinced that the formal tools of modern logic, set theory and the axiomatic method are not sufficient for providing mathematics and physics with satisfactory foundations. All of Hilbert, Gödel, Poincaré, Weyl and Bohr thought that intuition was an indispensable element in describing the foundations of science. They had very different reasons for thinking this, and they had very different accounts of what they called intuition. But they had in common that their views of mathematics and physics were significantly influenced by their readings of Kant. In the present volume, various views of intuition and the axiomatic method are explored, beginning with Kant’s own approach. By way of these investigations, we hope to understand better the rationale behind Kant’s theory of intuition, as well as to grasp many facets of the relations between theories of intuition and the axiomatic method, dealing with both their strengths and limitations; in short, the volume covers logical and non-logical, historical and systematic issues in both mathematics and physics.

This important new book synthesizes relevant research on the learning of mathematics from birth into the primary grades from the full range of these complementary perspectives. At the core of early math experts Julie Sarama and Douglas Clements's theoretical and empirical frameworks are learning trajectories—detailed descriptions of children’s thinking as they learn to achieve specific goals in a mathematical domain, alongside a related set of instructional tasks designed to engender those mental processes and move children through a developmental progression of levels of thinking. Rooted in basic issues of thinking, learning, and teaching, this groundbreaking body of research illuminates foundational topics on the learning of mathematics with practical and theoretical implications for all ages. Those implications are especially important in addressing equity concerns, as understanding the level of thinking of the class and the individuals within it, is key in serving the needs of all children.