This book provides a comprehensive guide to delivering analgesia and sedation to critically ill patients for professionals and caregivers being involved in the management of these patients. It discusses and explains in detail the advantages and limitations of each drug and device using clear flowcharts, diagrams and tables. Furthermore, it explores the new drugs and – above all – new sedation delivery systems, particularly those for administering volatile anesthetics on ICUs. This book is a valuable and practical resource for anesthesists, intensivists and emergency physicians interested in sedation.

There have been many developments in anaesthesia since Joseph Priestley discovered nitrous oxide. Covering new anaesthetics, the molecular and cellular mechanisms of anaesthesia and the non-hypnotic effects of anaesthetics and other medical gases, Gases in Medicine combines reviews of current research from both academic and clinical perspectives and provides an historical framework in which this research may be placed. Encompassing a wide range of topics including intravenous anaesthetics, neural processes and the 1997 Priestley Lecture on nitric oxide, this book offers an accessible summary of anaesthesia along with the current best research. Also included is the BOC Centenary Lecture, which gives a perspective on anaesthesia for the 21st century. This book will be welcomed by readers in academia and medicine as an illustration of the diversity of research into anaesthesia and the associated history of this fascinating subject.

Anesthesia Equipment: Principles and Applications, 2nd Edition, by Dr. Jan Ehrenwerth and Dr. James B. Eisenkraft, offers expert, highly visual, practical guidance on the full range of delivery systems and technology used in practice today. It equips you with the objective, informed answers you need to ensure optimal patient safety. "This is a comprehensive, up-to-date reference textbook covering all aspects of physics and equipment for the modern American anaesthetist. It may be helpful to those studying for American fellowship examinations but is not suited to preparation for the UK FRCA examinations." Reviewed by: I.Wrench on behalf of the British Journal of Anaesthesia, Feb 2014 Make informed decisions by expanding your understanding of the physical principles of equipment, the rationale for its use, delivery systems for inhalational anesthesia, systems monitoring, hazards and safety features, maintenance and quality assurance, special situations/equipment for non-routine adult anesthesia, and future directions for the field. Ensure patient safety with detailed advice on risk management and medicolegal implications of equipment use. Apply the most complete and up-to-date information available on machines, vaporizers, ventilators, breathing systems, vigilance, ergonomics, and simulation. Visualize the safe and effective use of equipment thanks to hundreds of full-color line drawings and photographs. Access the complete text and images online, fully searchable, at www.expertconsult.com.

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

The first book dedicated exclusively to plasma medicine for graduate students and researchers in physics, engineering, biology, medicine and biochemistry.

This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.

Prepared by authors based in the UK, this highly practical, illustrated guide continues to provide an up-to-date introduction to anaesthetic equipment and its use in clinical practice. An invaluable resource for all those who work with anaesthetic equipment, including anaesthetists studying for the FRCA examinations, nurses and operating department practitioners, this new edition has been completely updated to reflect current equipment and training requirements. Lavishly illustrated throughout with colour photos and clearly-drawn line illustrations, Essentials of Anaesthetic Equipment, third edition, retains the superbly organized and easy-to-read format that has made the previous two editions such a success. The same portable size is retained for the new edition An ideal book for the busy trainee or practitioner to carry around the hospital and 'dip into' when the opportunity presents A selection of MCQs is included at the end of each chapter providing an opportunity for the reader to test their knowledge - an ideal aid to exam preparation Highly illustrated with colour photographs and diagrams throughout to aid recognition in the clinical environment and demonstrates essential points Standardised format used for each piece of equipment: components, mechanism of action, problems in practice and safety features Summary boxes in every chapter highlighting key points and safety considerations help the reader remember key information and breaks down the text into manageable chunks. Especially helpful when preparing for exams Equipment checklists include essential information that all users of anaesthetic equipment need to know The content for the new edition reflects more closely the current FRCA syllabus New section on latex allergy Illustrations of now-obsolete equipment replaced with the latest models in use Discussion of bispectral monitoring now included Chapter on electrical safety expanded Chapter on sterilisation and cleaning added Rapid infusion devices discussed

The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.

Blood gas tests are a group of tests that are widely used and essential for the evaluation and management of a patient's ventilation, oxygenation, and acid-base balance, often in emergent situations, and along with blood gases are other critical care analytes measured on blood: calcium, magnesium, phosphate, and lactate. Blood Gases and Critical Care Testing: Clinical Interpretations and Laboratory Applications, Third Edition, serves as your single most important reference for understanding blood gases and critical care testing and interpretation. The third edition of this classic book is a complete revision and provides the fundamentals of blood gas (pH, pCO2, pO2) and other critical care tests (calcium, magnesium, phosphate, and lactate), including the history, the definitions, the physiology, and practical information on sample handling, quality control and reference intervals. Case examples with clear clinical interpretations of critical care tests have been included to all chapters. This book will serve as a valuable and convenient resource for clinical laboratory scientists in understanding the physiology and clinical use of these critical care tests and for providing practical guidelines for successful routine testing and quality monitoring of these tests. - Provides a step-by-step approach for organizing and evaluating clinical blood gas and critical care test results - Describes several calculated parameters that are used by clinicians for evaluating a patient's pulmonary function and oxygenation status and discusses clinical examples of their use - This new edition includes more detailed information about reference intervals, not only for arterial blood, but for venous blood and umbilical cord blood, and for pH in body fluids - Covers practical information on sample handling and quality control issues for blood gas testing

Almost every modern manufacturing process relies on industrial gases, and sales of such gases are expected to rise by around 45% over the next five years. Here, experienced and authoritative experts from one of the two world's largest producer of industrial gases impart their knowledge on atmospheric, noble and synthesized gases, carbon dioxide, LNG, acetylene and other fuel gases, as well as special and medical gases. Modern applications, e.g., the use of hydrogen in fuel cells, are included as well. This practical text is rounded off by a section on logistics.