It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. In the second part of the book, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process.

There has been international concern over the association of kava products and serious hepatotoxicity. Regulatory action banning these products in Europe has been controversial. The objective of this report is to investigate the possibility of hepatotoxicity with kava. It contains a description of kava and provides safety information as well as information on regulatory issues, conclusions and recommendations by the Committee appointed to handle this enquiry.

Here is the essential guide for librarians and teachers who want to develop a quality, curriculum-based graphic novel collection—and use its power to engage and inform middle and high school students. Connecting Comics to Curriculum: Strategies for Grades 6–12 provides an introduction to graphic novels and the research that supports their use in schools. The book examines best curriculum practices for using graphic novels with students in grades 6–12, showing teachers and school librarians how they can work together to incorporate these materials across the secondary curriculum. Designed to be an essential guide to harnessing the power of graphic novels in schools, the book covers every aspect of graphic novel use in libraries and classrooms. It illuminates the criteria for selecting titles, explores collection development strategies, and suggests graphic novel tie-ins for subjects taught in secondary schools. One of the first books to provide in-depth lesson plans for teaching a variety of middle and high school standards with graphic novels, the guide offers suggestions for differentiating instruction and includes resource lists of recommended titles and websites.

Appropriate for any public library collection, this book provides a comprehensive readers' advisory guide for Japanese manga and anime, Korean manhwa, and Chinese manhua. Japanese manga and anime, Korean manhwa, and Chinese manhua are Asian graphic novels and animated films that have gained great popularity in the last ten years and now are found in most public library collections. Mostly Manga: A Genre Guide to Popular Manga, Manhwa, Manhua, and Anime is the first readers' advisory guide to focus on this important body of literature. This guide provides information on all of the major manga and anime formats and genres, covering publications from the early 1990s to the present. It identifies important titles historically and provides a broad representation of what is available in each format. Selected major titles are described in detail, covering the general plot as well as grade level and pertinent awards. The author also discusses common issues related to manga and anime, such as terminology, content and ratings, and censorship.

The number of individuals diagnosed with posttraumatic stress disorder has increased in the past decade, not only in the military and veteran population but within the civilian population as well. Traditional treatments such as pharmacotherapy and psychotherapy have provided less-than-ideal results proving to be less effective when used alone to treat the disorder. Complementary and Alternative Medicine for PTSD supplements these traditional treatments, using new and effective techniques to fill the therapeutic void. The alternative therapies covered include acceptance and commitment therapy, acupuncture, alternative pharmacology, canine assistive therapy, family focused interventions, internet and computer-based therapy, meditation techniques, mobile applications, recreational therapy, resilience training, transracial magnetic stimulation, virtual reality exposure therapy, and yoga. Each chapter delivers the most up-to-date understanding of neurobiology, best practices, and key points for clinicians and patients considering inclusion of these treatments in patient care. Drs. David Benedek and Gary Wynn offer insight into the future of complementary and alternative medicine, shining a light onto how these techniques fit into clinical practice to create the most beneficial treatments for the patient. This book is both an essential resource and practical guide to everyday clinical interactions. It is a necessary addition to the medical library for students and senior clinicians alike.

Creating Coordination in the Cerebellum provides a multidisciplinary collection of chapters on the cerebellum with topics covering the entire spectrum from development and molecular neurobiology, cell physiology and plasticity to motor control, system physiology, functional imaging and pathology. The book not only presents novel discoveries obtained with recently developed technologies, but also gives new general concepts in global issues of cerebellar development and functions. By doing so it sets the standard for cerebellar research of the 21st century.* Provides a complete overview of current cerebellar research* Includes color illustrations* Contains contributions from renowned cerebellar scientists

Introducing poetry, prose, songs and theatre from Nigeria, this engaging volume blends translated extracts with a rich commentary on the historical development and modern context of this hugely creative culture. Examining imaginative prose-writing, the tale tradition, popular song, Islamic religious poetry and modern TV drama amongst other topics, this is a clear and accessible book on a literary culture that has previously been little-known to the English-speaking readership.

Demons like Rara are supposed to cause mischief in the mortal world and draw humans to darkness. They're not supposed to help mortals and they're definitely not supposed to fall in love with them! But that's just what happens when Rara enters high school, where a hot guy named Retsu Aku calls her "Gaba Kawa"! While demons gain power by causing mischief, the opposite is also true--if Rara uses any of her powers to help mortals, she'll immediately lose that very power. If she loses enough power, she'll disappear! Poor Rara. What's a "Gaba Kawa" demon to do? -- VIZ Media