This book reviews key recent advances and new frontiers within psychiatric research and clinical practice. These advances either represent or are enabling paradigm shifts in the discipline and are influencing how we observe, derive and test hypotheses, and intervene. Progress in information technology is allowing the collection of scattered, fragmented data and the discovery of hidden meanings from stored data, and the impacts on psychiatry are fully explored. Detailed attention is also paid to the applications of artificial intelligence, machine learning, and data science technology in psychiatry and to their role in the development of new hypotheses, which in turn promise to lead to new discoveries and treatments. Emerging research methods for precision medicine are discussed, as are a variety of novel theoretical frameworks for research, such as theoretical psychiatry, the developmental approach to the definition of psychopathology, and the theory of constructed emotion. The concluding section considers novel interventions and treatment avenues, including psychobiotics, the use of neuromodulation to augment cognitive control of emotion, and the role of the telomere-telomerase system in psychopharmacological interventions.

In Zurich at the 7th International Annual Meeting of the Society of Nuclear Hedicine in Europe, held in 1969, a group of young scientists from eleven countries dedicated some papers to the memory of Georg von Hevesy. The papers were published in a book entitled "Frontiers of Nuclear Medicine" (Springer-verlag Berlin, Heidelberg, New York). On the occasion of the Second International World Congress of Nuclear Medicine and Biology held in 1978 in Washington D.C., under the presidency of Henry N.Wagner,Jr., a group of young scientists again dedicated important papers from the Congress to the memory of Georg von Hevesy. This book consists of these papers, which present new results in the field of Nuclear Medicine reported by physicians, physicists, chemists, engineers, and computer scientists. The Georg von Hevesy Foundation of Nuclear Medicine in Zurich, Switzerland together with the president of the Second World Congress of Nuclear Medicine, Henry N.Wagner,Jr., have been the major forces in arranging publication of this book. The Georg von Hevesy Foundation is sponsoring the Hevesy Prize for Nuclear Medicine, the Hevesy Medal, and the Hevesy Memorial Lecture.

Primary care medicine is the new frontier in medicine. Every nation in the world has recognized the necessity to deliver personal and primary care to its people. This includes first-contact care, care based in a posi tive and caring personal relationship, care by a single healthcare pro vider for the majority of the patient's problems, coordination of all care by the patient's personal provider, advocacy for the patient by the pro vider, the provision of preventive care and psychosocial care, as well as care for episodes of acute and chronic illness. These facets of care work most effectively when they are embedded in a coherent integrated approach. The support for primary care derives from several significant trends. First, technologically based care costs have rocketed beyond reason or availability, occurring in the face of exploding populations and diminish ing real resources in many parts of the world, even in the wealthier nations. Simultaneously, the primary care disciplines-general internal medicine and pediatrics and family medicine-have matured significantly.

In this intriguing narrative, David Dary charts how American medicine has evolved since 1492, when New World settlers first began combining European remedies with the traditional practices of the native populations. It’s a story filled with colorful characters, from quacks and con artists to heroic healers and ingenious medicine men, and Dary tells it with an engaging style and an eye for the telling detail. Dary also charts the evolution of American medicine from these trial-and-error roots to its contemporary high-tech, high-cost pharmaceutical and medical industry. Packed with fascinating facts about our medical past, Frontier Medicine is an engaging and illuminating history of how our modern medical system came into being.

In September 1925 the first class of medical students was admitted to the University of Rochester School of Medicine and Dentistry. On January 4, 1926 the Strong Memorial Hospital was officially opened. The first patient was admitted the next day. On January 7th Dr. John J. Morton, Jr., newly appointed Chief of Surgery, performed the first operation. Ten days later the first baby was delivered. From these small beginnings the University of Rochester Medical Center had a steady and strong growth into the internationally renowned center of teaching, research and patient care that it is today. In recognition of its semicentennial the Medical Center con ducted a series of events during the 1975 - 76 year in which medi cal faculty and staff~ alumni, community physicians and distin guished visitors participated. This symposium on "Frontiers of Medicine" was a climactic event of the year's program. The twelve outstanding physicians and scientists undertook to look forward, in selected areas of biological science and medicine, to what promise there may be for developments to come which will significantly affect mankind's health and the quality of life. Four areas were chosen for discussion to cover the span of human life and to include aspects of it which are of vital in terest and in which significant developments now seem to be prob able in the years ahead. So far as possible the presentations sought to cover the basic science, the clinical and the sociologic aspects of each subject area.