This book provides a comprehensive overview of the use of noble metal nanoparticles for bioimaging and biosensing. It starts with a review on the synthesis, characterization, optical properties, and bioconjugation of noble metal nanoparticles, followed by introduction of various biodetection techniques based on noble metal nanoparticles. In between these topics, microfabrication of biosensing chips and the use of microfluidics to enhance biosensing performance are discussed.

Electrochemical Biosensors summarizes fundamentals and trends in electrochemical biosensing. It introduces readers to the principles of transducing biological information to measurable electrical signals to identify and quantify organic and inorganic substances in samples. The complexity of devices related to biological matrices makes this challenging, but this measurement and analysis are critically valuable in biotechnology and medicine. Electrochemical biosensors combine the sensitivity of electroanalytical methods with the inherent bioselectivity of the biological component. Some of these sensor devices have reached the commercial stage and are routinely used in clinical, environmental, industrial and agricultural applications. - Describes several electrochemical methods used as detection techniques with biosensors - Discusses different modifiers, including nanomaterials, for preparing suitable pathways for immobilizing biomaterials at the sensor - Explains various types of signal monitoring, along with several recognition systems, including antibodies/antigens, DNA-based biosensors, aptamers (protein-based), and more

Nanomaterials for Biosensors: Fundamentals and Applications provides a detailed summary of the main nanomaterials used in biosensing and their application. It covers recent developments in nanomaterials for the fabrication of biosensor devices for healthcare diagnostics, food freshness and bioprocessing. The various processes used for synthesis and characterization of nanostructured materials are examined, along with the design and fabrication of bioelectronic devices using nanostructured materials as building blocks. Users will find the fundamentals of the main nanomaterials used in biosensing, helping them visualize a systematic and coherent picture of how nanomaterials are used in biosensors. The book also addresses the role of bio-conjugation of nanomaterials in the construction of nano-biointerfaces for application in biosensors. Such applications, including metal nanoparticles, metal oxide nanoparticles, nanocomposites, carbon nanotubes, conducting polymers and plasmonic nanostructures in biosensing are discussed relative to each nanomaterial concerned. Finally, recent advancements in protein functionalized nanomaterials for cancer diagnostics and bio-imaging are also included. - Provides a detailed study on how nanomaterials are used to enhance sensing capabilities in biosensors - Explains the properties, characterization methods and preparation techniques of the nanomaterials used in biosensing - Arranged in a material-by-material way, making it clear how each nanomaterial should be used

The Development Of Microscopy Revolutionized The World Of Cell And Molecular Biology As We Once Knew It And Will Continue To Play An Important Role In Future Discoveries. Bioimaging: Current Concepts In Light And Electron Microscopy Is The Optimal Text For Any Undergraduate Or Graduate Bioimaging Course, And Will Serve As An Important Reference Tool For The Research Scientist. This Unique Text Covers, In Great Depth, Both Light And Electron Microscopy, As Well As Other Structure And Imaging Techniques Like X-Ray Crystallography And Atomic Force Microscopy. Written In A User-Friendly Style And Covering A Broad Range Of Topics, Bioimaging Describes The State-Of-The-Art Technologies That Have Powered The Field To The Forefront Of Cellular And Molecular Biological Research.

This book describes the rational design, development and application of nucleic acid amplification strategies for biosensing, bioimaging and biomedicine. It consists of fifteen chapters demonstrating the use of these strategies in various areas, including fluorescence techniques, Chemiluminescence biosensors, electrochemiluminescence biosensors, colorimetric assays, surface plasmon resonance technologies, electrochemical DNA sensors, photoelectrochemical biosensor, nanopore sensors, quartz crystal microbalance, fluorescence imaging, surface-enhanced Raman spectroscopy, in vitro and in vivo metal ions detection, theranostics and microdroplet chips. Offering a collection of reviews illustrating the latest advances in biochemical analysis and therapeutics, the book shares valuable insights into current challenges and future prospects, making it a valuable resource for a wide readership in the various fields of biosensing, bioimaging and biomedicine.

Topics discussed in this book include: cell imaging, multiphoton microscopy for biomedical studies, molecular imaging, infrared imaging, biomedical magnetic imaging, and microscopy with laser-trapped particles. The book also deals with nanosurgery with light, the effects of ultrasound on tissue, diagnostics, near- and far-infrared transmission of biomedical information, and cell sensors.

Sensors for measuring and detecting chemical and biological substances are comprehensively used and are, for the most part, unobtrusive. They can help monitor our health through alerting us to chemical or biological changes in our bodies, our environment through checking air quality or pollution levels and they can contribute towards a more sustainable future. Polymer-based sensors are the subject of much attention due to their ability to collect molecules on their flexible sensory surfaces. However, most petroleum-based polymers are not renewable, leading to problems of waste-disposal. By using renewable materials, such as paper, cotton or starch, these problems can be overcome. This book reviews the current state-of-play in renewable-material-based chemical sensors and biosensors, and suggests applications in industry, environment and biomedicine.

Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part B, Volume 185 presents many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. This volume covers various topics, including tissue and protein fibrils imaging by AIE active molecules, theranostic and photodynamic therapy applications of AIE materials for cancer cell treatment, and AIE active polymers and MOF materials for biological applications. Fluorescence-based monitoring and diagnosis platforms furnish extensive insights into the molecular mechanisms of cellular processes, helping us precisely guide therapeutics. - Offers an overview of AIE active polymer materials and their bio-imaging applications - Elucidates on tissue and protein fibrils imaging by AIE active molecules - Describes theranostic and photodynamic therapy applications of AIE materials for cancer cell treatment