As a leader you are not only responsible for your own productivity, but for helping those on your team be as productive as possible, and not just at work, but at home as well. Neen made this book easy to digest and implement the strategies immediately. It's not just a book of theory or unrealistic tips for someone who keeps laminated checklists for their family members. Neen provides nuggets of wisdom and then weaves in the insights from other experts that it is like 10 books rolled into one.--Back cover.

Organized by Alessandra Carbone ( IHeS, Bures-sur-Yvette, France ) Organized by Misha Gromov ( IHeS, Bures-sur-Yvette, France ) Organized by Fran ois K(r)p s ( CNRS-Genopole-, evry, France ) Organized by Eric Westhof ( Universit(r) Louis-Pasteur, Strasbourg, France ). This proceedings volume explores the pathways and mechanisms by which constituent residues interact and fold to yield native biological macromolecules (catalytic RNA and functional proteins), how ribosomes and other macromolecular complexes self-assemble, and relevant energetics considerations. At the week-long interactive conference, some 20 leading researchers reported their most pertinent results, confronting each other and an audience of more than 150 specialists from a wide range of scientific disciplines, including structural and molecular biology, biophysics, computer science, mathematics, and theoretical physics. The fourteen papers OCo and audience interaction OCo are edited and illustrated versions of the transcribed oral presentations. The proceedings have been selected for coverage in: . OCo Biochemistry & Biophysics Citation Index(tm). OCo Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings). OCo CC Proceedings OCo Biomedical, Biological & Agricultural Sciences. Contents: Evolution-Based Genome Analysis: An Alternative to Analyze Folding and Function in Proteins (S Benner); Conformation of Charged Polymers: Polyelectrolytes and Polyampholytes (J-F Joanny); Statistically Derived Rules for RNA Folding (M Zuker); Experimental Approaches to RNA Folding (S Woodson); Some Questions Concerning RNA Folding (F Michel); RNA Folding in Ribosome Assembly (J R Williamson); From RNA Sequences to Folding Pathways and Structures: A Perspective (H Isamber t); An Evolutionary Perspective on the Determinants of Protein Function and Assembly (O Lichtarg e); Some Residues are more Equal than Others: Application to Protein Classification and Structure Prediction (A Kister & I Gelfan d); Structure-Function Relationships in Polymerases (M Delarue); The Protein-Folding Nucleus: From Simple Models to Real Proteins (L Mirn y); Chaperonin-Mediated Protein Folding (D Thirumalai); Virus Assembly and Maturation (J E Johnson); The Animal in the Machine: Is There a Geometric Program in the Genetic Program? (A Danchin). Readership: Researchers, academics and graduate students in structural biology, cellular and molecular biology, biophysics, biochemistry and biomathematics/bioinformatics."

BIG BOOK OF HISTORY Learning Just Became BIG FUN! Families, schools, and churches can unfold 15 feet of the most interesting history of the world. This easy to follow, color-coded, multi-stream timeline teaches six thousand years of world history to children ages seven through thirteen. These exciting facts and so much more wait inside: who were the first emperors of China and Rome what discovery unlocked the secrets of a forgotten language how modern robotics had its roots in the tea dolls of Japan where Christians faced death for the entertainment of thousands why the languages of Greek and Hebrew were used to write the Bible and how the Age of Discovery meant wealth some, and the destruction of civilization for others. Understanding how the past has shaped our future will inspire young learners to make history for themselves!

Tummy time is important for babies' physical development. It builds strength in their necks and upper bodies, eventually enabling them to roll over, sit, and crawl. Keep their brains busy too with this two-sided panorama of images designed to attract and keep their attention from birth to 12 months.

A page-turning science-fiction thriller from the author of Paradox Bound and the Ex-Heroes series. Step into the fold. It's perfectly safe. The folks in Mike Erikson's small New England town would say he's just your average, everyday guy. And that's exactly how Mike likes it. Sure, the life he's chosen isn’t much of a challenge to someone with his unique gifts, but he’s content with his quiet and peaceful existence. That is, until an old friend presents him with an irresistible mystery, one that Mike is uniquely qualified to solve: far out in the California desert, a team of DARPA scientists has invented a device they affectionately call the Albuquerque Door. Using a cryptic computer equation and magnetic fields to “fold” dimensions, it shrinks distances so that a traveler can travel hundreds of feet with a single step. The invention promises to make mankind’s dreams of teleportation a reality. And, the scientists insist, traveling through the Door is completely safe. Yet evidence is mounting that this miraculous machine isn’t quite what it seems—and that its creators are harboring a dangerous secret. As his investigations draw him deeper into the puzzle, Mike begins to fear there’s only one answer that makes sense. And if he’s right, it may only be a matter of time before the project destroys…everything. A cunningly inventive mystery featuring a hero worthy of Sherlock Holmes and a terrifying final twist you’ll never see coming, The Fold is that rarest of things: a genuinely page-turning science-fiction thriller.

Walter Mosley is one of America’s bestselling novelists, known for his critically acclaimed series of mysteries featuring private investigator Easy Rawlins. His writing is hard-hitting, often limned with a political subtext, and aimed at a broad audience. Years ago, when Mosley was working on a doctorate in political theory, he envisioned writing very different kinds of books from those for which he has become celebrated. But once you’ve been tagged as a novelist, and in Mosley’s case, a genre writer, even a bestselling one, it is hard to get an airing for ideas that cross those boundaries. Folding the Red into the Black has grown out of Mosley’s public talks, which have gotten both enthusiastic and agitated responses, making him feel the ideas in those talks should be explored in greater depth. Mosley’s is an elastic mind, and in this short polemic he frees himself to explore some novel ideas. He draws on personal experiences and insights as an African-American, a Jew, and one of our great writers to present an alternative manifesto of sorts: “We need to throw off the unbearable weight of bureaucratic capitalist and socialist demands; demands that exist to perpetuate these systems, not to praise and raise humanity to its full promise. And so I propose the word, the term Untopia.”

Many designers use folding techniques in their work to make three-dimensional forms from two-dimensional sheets of fabric, cardboard, plastic, metal, and many other materials. This unique book explains the key techniques of folding, such as pleated surfaces, curved folding, and crumpling. It has applications for architects, product designers, and jewelry and fashion designers An elegant, practical handbook, Folding for Designers explains over 70 techniques explained with clear step-by-step drawings, crease pattern drawings, and specially commissioned photography. All crease pattern drawings are available to view and download from the Laurence King website.

This text presents the results of broad, interdisciplinary effort to study proteins in physical and evolutionary perpective. Among authors are physicists, computational, chemists, crystallographers and evolutionary biologists. Experimental and theoretical developments from molecules to cells are presented, providing a broad picture of modern biophysical chemistry.

Information on our detailed genetic code is increasing at a dramatic pace. We need to understand how that is translated into the three-dimensional structure of proteins in order to make use of the information. Progress in this field is hampered by the lack of precise force fields and of efficient codes for finding equilibrium configurations of heteropolymers. However, there has been rapid advance in recent years, and this volume discusses that.

Infrared spectroscopy is a new and innovative technology to study protein folding/misfolding events in the broad arsenal of techniques conventionally used in this field. The progress in understanding protein folding and misfolding is primarily due to the development of biophysical methods which permit to probe conformational changes with high kinetic and structural resolution. The most commonly used approaches rely on rapid mixing methods to initiate the folding event via a sudden change in solvent conditions. Traditionally, techniques such as fluorescence, circular dichroism or visible absorption are applied to probe the process. In contrast to these techniques, infrared spectroscopy came into play only very recently, and the progress made in this field up to date which now permits to probe folding events over the time scale from picoseconds to minutes has not yet been discussed in a book. The aim of this book is to provide an overview of the developments as seen by some of the main contributors to the field. The chapters are not intended to give exhaustive reviews of the literature but, instead to illustrate examples demonstrating the sort of information, which infrared techniques can provide and how this information can be extracted from the experimental data. By discussing the strengths and limitations of the infrared approaches for the investigation of folding and misfolding mechanisms this book helps the reader to evaluate whether a particular system is appropriate for studies by infrared spectroscopy and which specific advantages the techniques offer to solve specific problems.