The concept of flow injection analysis (FIA) was introduced in the mid-seventies. It was preceded by the success of segmented flow analysis, mainly in clinical and environmental analysis. This advance, as well as the development of continuous monitors for process control and environmental monitors, ensured the success of the FIA methodology. As an exceptionally effective means of mechanization for various procedures of wet chemical analysis, the FIA methodology, in use with a whole arsenal of detection methods of modern analytical chemistry, proved to be of great interest to many.The fast and intensive development of the FIA methodology was due to several factors essential for routine analytical determinations, such as very limited sample consumption, the short analysis time based on a transient signal measurement in a flow-through detector and an on-line carrying out difficult operations of separation, preconcentration or physicochemical conversion of analytes into detectable species.Twenty-year studies by numerous research groups all over the world have provided significant progress in the theoretical description of dispersion phenomena in FIA and various operations of physicochemical treatment of the analyte. This volume is devoted to the presentation of the current status of development of the instrumentation for FIA and the many fields of its practical applications, based on an extensive bibliography of original research publications.

Annotation The first five chapters in this manual for users and manufacturers of FIA technology describe the principles and properties of detection methods, including molecular and atomic spectroscopy detection methods, electrochemical methods, enzymatic methods and immunoassays, and photoacoustic spectroscopic detection. Chapters six and seven cover on-line sample processing and speciation analysis. Chapter eight (the longest chapter) discusses applications of flow injection methods in routine analysis, including environmental applications and analysis of food products and biological and mineral materials, clinical analysis, pharmaceutical and biotechnology applications, and process analysis. The last three chapters cover sequential and batch injection techniques, review commercially available instrumentation, and discuss current trends in developments of flow analysis. Annotation copyrighted by Book News, Inc., Portland, OR.

This Second edition of the flow injection analysis (FIA) text which has become a standard in the field in four languages, is written by two pioneers in the field, who have themselves discovered many of the techniques and designed much of the equipment employed in FIA. Newly revised to account for the many recent developments in FIA, this book presents the state-of-the-art in FIA theory, techniques, and future trends. Specific topics covered include continous-flow analyzers, chemical kinetics in an FIA system, theory of dispersion related to FIA, single-line FIA manifolds, FIA determinations based on separation processes, commercially available flow-injection analyzers, the FIA laboratory--a microconduit-based pedagogical system, review of the flow-injection literature, and flow injection analysis now and in the future.

This valuable resource covers the principles of analytical instrumentation used by today's chemists and biologists and presents important advances in instrumentation, such as the drive to miniaturise and lab-on-a-chip devices. In terms of the lab-based analytical instrumentation, the five main categories of technique—spectroscopic, chromatographic, electrochemical, imaging and thermoanalytical, are included and presented in a practical, not theoretical way. Including relevant examples and applications in a number of fields such as healthcare, environment and pharmaceutical industry this book provides a complete overview of the instruments used within the chemistry industry, making this an important tool for professionals and students alike.

Sample Introduction Systems in ICPMS and ICPOES provides an in-depth analysis of sample introduction strategies, including flow injection analysis and less common techniques, such as arc/spark ablation and direct sample insertion. The book critically evaluates what has been accomplished so far, along with what can be done to extend the capabilities of the technique for analyses of any type of sample, such as aqueous, gaseous or solid. The latest progress made in fields, such as FIA, ETV, LC-ICP-MS and CE-ICP-MS is included and critically discussed. The book addresses problems related to the optimization of the system, peak dispersion and calibration and automatization. - Provides contributions from recognized experts that give credibility to each chapter as a reference source - Presents a single source, providing the big picture for ICPMS and ICPOES - Covers theory, methods, selected applications and discrete sampling techniques - Includes access to core data for practical work, comparison of results and decision-making

This is a practical guide for first-time and experienced users of Flow Injection Analysis (FIA). It gives, not a detailed theoretical analysis, but a ``nuts and bolts'' approach to the description of the technique and how it can be utilized to solve analytical chemical problems.The advantages of flow injection, how, when, why and where it works are all fully explained. Criteria for the choice of hardware and useful hints for maintenance are provided. The large variety of detectors suitable to combine with FIA are discussed, as are special modes of operation, their advantages and their limitations, and also conversion of batch methods to FIA methods. Numerous in-depth descriptions of applications of FIA techniques in water, soil, pharmaceutical and industrial analysis are featured, and a complete bibliography is included.The authors have spent several years demonstrating, lecturing and using FIA and the basic outline of their book closely follows the schedule of the FIA workshops they have taught. It will be an invaluable tool for all chemists who perform analyses on a routine basis.

The book presents developments and applications of these methods, such as NMR, mass, and others, including their applications in pharmaceutical and biomedical analyses. The book is divided into two sections. The first section covers spectroscopic methods, their applications, and their significance as characterization tools; the second section is dedicated to the applications of spectrophotometric methods in pharmaceutical and biomedical analyses. This book would be useful for students, scholars, and scientists engaged in synthesis, analyses, and applications of materials/polymers.

Flow Analysis: A Practical Guide reviews flow techniques for automating chemical analysis with the goal of increasing efficiency and producing better analytical results. Various applications for flow techniques are reviewed including industrial process monitoring (for example, foods and beverages, drugs and pharmaceuticals); as well as agricultural, life science, radioactivity, and environmental analysis with an emphasis on the latter. This book is a valuable resource for young scientists or graduate-level students who want to learn how to introduce flow techniques into their experiments, and for experts who need specific and technical details to develop complete experimental systems. - Includes descriptions of the theoretical and technical bases of the most important flow techniques - Focuses on new trends in the field such as using flow techniques for radioactivity and environmental applications - Features instructions for coupling different types of detectors online with flow systems

High Throughput Analysis for Early Drug Discovery offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each chapter or section begins with a description of the synthesis approach and its advantages. The description of various combinatorial and high-throughput parallel synthesis techniques provide a relevant point of entry for synthetic chemists who need to set up appropriate characterisation methods for his/her organisation. This is an invaluable resource for all organic and analytical chemists in the pharmaceutical, agrochemical, and biotechnology fields who are either involved in, or beginning to investigate combinatorial techniques to increase overall efficiency and productivity. First reference to focus on the analytical side of synthesis