Fast Facts Clinical Trials In Oncology
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Author |
: R. Kay |
Publisher |
: Karger Medical and Scientific Publishers |
Total Pages |
: 110 |
Release |
: 2020-07-17 |
ISBN-10 |
: 9781912776689 |
ISBN-13 |
: 1912776685 |
Rating |
: 4/5 (89 Downloads) |
Synopsis Fast Facts: Medical Statistics by : R. Kay
Using real examples from oncology trials, but keeping it simple, this concise resource explains the basic principles of medical statistics so that you can better appraise clinical trial results. Key concepts covered in this book include: • hypothesis testing • Kaplan–Meier curves and other graphic representations of data • calculating the power of a study • the stopping rules for efficacy and futility. ' Fast Facts: Medical Statistics' is aimed at all clinicians, clinical scientists, medical writers and regulatory personnel who need a better understanding of the statistical terms and methods used in the planning of studies and the analysis of clinical trial data. If you have ever wanted to know what a type I error is, how an odds ratio is calculated or what a forest plot is really all about, then this is the book for you. Contents: • Statistical inference • Analysis of time-to-event endpoints • Power and sample size • Multiplicity • Interim analysis • Modeling • Graphical methods
Author |
: A. Hackshaw |
Publisher |
: Karger Medical and Scientific Publishers |
Total Pages |
: 120 |
Release |
: 2020-12-18 |
ISBN-10 |
: 9781912776740 |
ISBN-13 |
: 191277674X |
Rating |
: 4/5 (40 Downloads) |
Synopsis Fast Facts: Clinical Trials in Oncology by : A. Hackshaw
Written by leading experts, 'Fast Facts: Clinical Trials in Oncology' will enhance the reader’s ability to critically evaluate published evidence. Assuming little or no prior knowledge, the book sets out clearly the fundamental features of clinical trials. The key attributes of Phase I–III trials of pharmaceutical products are described, as are trials of surgical procedures, radiation therapy and advanced therapies. The processes and documentation required to set up and conduct a trial are outlined, and the authors describe how trial data and real-world evidence are used to improve care. Although this concise colorful book focuses on oncology, the principles apply equally to interventions in other areas of practice. It will prove invaluable to medical, pharmaceutical and allied health professionals who want, or need, an overview of how contemporary clinical trials are designed and conducted.
Author |
: Allan Hackshaw |
Publisher |
: Karger Medical and Scientific Publishers |
Total Pages |
: 120 |
Release |
: 2020-12-18 |
ISBN-10 |
: 9781912776733 |
ISBN-13 |
: 1912776731 |
Rating |
: 4/5 (33 Downloads) |
Synopsis Fast Facts: Clinical Trials in Oncology by : Allan Hackshaw
Written by leading experts, 'Fast Facts: Clinical Trials in Oncology' will enhance the reader’s ability to critically evaluate published evidence. Assuming little or no prior knowledge, the book sets out clearly the fundamental features of clinical trials. The key attributes of Phase I–III trials of pharmaceutical products are described, as are trials of surgical procedures, radiation therapy and advanced therapies. The processes and documentation required to set up and conduct a trial are outlined, and the authors describe how trial data and real-world evidence are used to improve care. Although this concise colorful book focuses on oncology, the principles apply equally to interventions in other areas of practice. It will prove invaluable to medical, pharmaceutical and allied health professionals who want, or need, an overview of how contemporary clinical trials are designed and conducted. Contents: • Fundamental features of clinical trials • Phase I trials • Phase II trials • Phase III trials • Trials of non-drug interventions • Setting up and conducting trials • Publishing trial results, changing clinical practice, and supporting evidence
Author |
: Stephanie Green |
Publisher |
: CRC Press |
Total Pages |
: 266 |
Release |
: 2012-05-09 |
ISBN-10 |
: 9781439814482 |
ISBN-13 |
: 1439814481 |
Rating |
: 4/5 (82 Downloads) |
Synopsis Clinical Trials in Oncology, Third Edition by : Stephanie Green
The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.
Author |
: Jayant S. Vaidya |
Publisher |
: |
Total Pages |
: 0 |
Release |
: 2010 |
ISBN-10 |
: OCLC:958734720 |
ISBN-13 |
: |
Rating |
: 4/5 (20 Downloads) |
Synopsis Breast Cancer by : Jayant S. Vaidya
Author |
: Allan Hackshaw |
Publisher |
: |
Total Pages |
: 0 |
Release |
: 2021 |
ISBN-10 |
: OCLC:1397884964 |
ISBN-13 |
: |
Rating |
: 4/5 (64 Downloads) |
Synopsis Fast Facts : Clinical Trials in Oncology by : Allan Hackshaw
Author |
: Eden Zabat Kan |
Publisher |
: Springer Publishing Company |
Total Pages |
: 207 |
Release |
: 2013-06-28 |
ISBN-10 |
: 9780826118943 |
ISBN-13 |
: 0826118941 |
Rating |
: 4/5 (43 Downloads) |
Synopsis Fast Facts for the Clinical Nursing Instructor by : Eden Zabat Kan
Print+CourseSmart
Author |
: Tomasz M. Beer |
Publisher |
: Diamedica |
Total Pages |
: 0 |
Release |
: 2012 |
ISBN-10 |
: 098232197X |
ISBN-13 |
: 9780982321973 |
Rating |
: 4/5 (7X Downloads) |
Synopsis Cancer Clinical Trials by : Tomasz M. Beer
A readable guide for anyone who is considering therapeutic options in addition to standard cancer therapy. The book seeks to share knowledge about cancer clinical trials with people living with cancer, their families and loved ones.
Author |
: Bernardo L. Rapoport |
Publisher |
: Karger Medical and Scientific Publishers |
Total Pages |
: 109 |
Release |
: 2020-10-20 |
ISBN-10 |
: 9783318068184 |
ISBN-13 |
: 3318068187 |
Rating |
: 4/5 (84 Downloads) |
Synopsis Fast Facts: Comprehensive Genomic Profiling by : Bernardo L. Rapoport
Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: • Genetic mutations and biomarkers • Understanding next-generation sequencing • Elements of comprehensive genomic profiles • Role in precision oncology • Predictive and prognostic biomarkers • Overcoming barriers to genotype-directed therapy
Author |
: Foss, Francine |
Publisher |
: Karger Medical and Scientific Publishers |
Total Pages |
: 101 |
Release |
: 2019-06-20 |
ISBN-10 |
: 9781912776184 |
ISBN-13 |
: 1912776189 |
Rating |
: 4/5 (84 Downloads) |
Synopsis Fast Facts: Peripheral T-cell Lymphoma by : Foss, Francine
The peripheral T-cell lymphomas (PTCLs) are a heterogenous group of rare entities. Whilst cytogenetic and molecular identifiers are being identified, accurate diagnosis remains challenging, requiring careful, expert integration of the clinical and pathological findings. The treatment of PTCL is also challenging. Protocols for the different subtypes are only just beginning to emerge, hindered by the complexities of conducting trials in such uncommon and varied conditions. While first-line treatment with conventional chemotherapy is seldom curative, patients who achieve remission may be eligible for stem cell transplantation, offering the possibility of long-term disease control if not cure. Targeted biologics are also being developed as unique cytotoxic markers are identified. 'Fast Facts: Peripheral T-Cell Lymphomas' is a new title in the Fast Facts extensive hemato-oncology library, written by experts in this emerging field. This handbook will be useful to anyone involved in the care of patients with PTCL, including haematologists, oncologists, specialist nurses and primary care providers, raising awareness of these rare lymphomas and the current – and emerging – approaches to diagnosis and treatment.