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The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.

From the earliest days of medicine to the present, case reports have been a critical aspect of clinical education and knowledge development. In this comprehensive volume, Dr. William C. Roberts, a renowned expert in the field, explores the rich history and ongoing importance of case reports in cardiology. Through engaging and insightful analysis, the book demonstrates how case reports have provided physicians with crucial insights into rare diseases, complex conditions, and groundbreaking treatments. Drawing on a vast range of sources, from ancient manuscripts to cutting-edge journals, it presents a unique perspective on the role of case reports in medical education and practice of valvular heart disease and analogous cardiac morbidities including carcinoid heart disease with a rich coverage on heart valve bioprosthesis. It underscores how case reports can be used to enhance diagnostic accuracy, identify new treatment options, and promote innovation in the field. In addition, the book provides valuable insights into the process of writing and publishing case reports, including tips for young physicians looking to break into the field. The book will be an indispensable guide to the history, practice, and ongoing significance of case reports for medical students, physicians, and researchers alike. Key features- Provides a rich repository of diverse case reports in cardiology published by the editor and his colleagues over 61 years Features 65 clinical case studies related to Valvular Heart Disease useful for medical students and practicing cardiologists Valuable resource for young physicians seeking to establish a foothold in medical research and academics

Every 37 seconds an American dies of cardiovascular disease. For nearly half of its victims atherosclerotic cardiovascular disease shows up suddenly with a heart attack or sudden death – as if appearing out of a fog. This is the disease that kills most men and women in the United States and knowing about it earlier makes common sense. Atherosclerosis starts silently in our teen years, and often tracks with poor lifestyle, and poorly controlled risk factors including poor nutrition, abnormal lipids, high BP, diabetes, tobacco use, sedentary behavior, and importantly, genetic predisposition. The development and progression of coronary atherosclerosis is a silent process and each year nearly 150,000 Americans present with fatal myocardial infarction as the one and only manifestation of this indolent disease. It is obvious that our current methods to identify and treat atherosclerotic vascular disease fail too many.

This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Current, comprehensive, and evidence-based Braunwald's Heart Disease remains the most trusted reference in the field and the leading source of reliable cardiology information for practitioners and trainees worldwide. The fully updated 12th Edition continues the tradition of excellence with dependable, state-of-the-art coverage of new drugs, new guidelines, more powerful imaging modalities, and recent developments in precision medicine that continue to change and advance the practice of cardiovascular medicine. Written and edited by global experts in the field, this award-winning text is an unparalleled multimedia reference for every aspect of this complex and fast-changing area. - Offers balanced, dependable content on rapidly changing clinical science, clinical and translational research, and evidence-based medicine. - Includes 76 new contributing authors and 14 new chapters that cover Artificial intelligence in Cardiovascular Medicine; Wearables; Influenza, Pandemics, COVID-19, and Cardiovascular Disease; Tobacco and Nicotine Products in Cardiovascular Disease; Cardiac Amyloidosis; Impact of the Environment on Cardiovascular Health, and more. - Features a new introductory chapter Cardiovascular Disease: Past, Present, and Future by Eugene Braunwald, MD, offering his unique, visionary approach to the field of cardiology. Dr. Braunwald also curates the extensive, bimonthly online updates that include "Hot Off the Press" (with links to Practice Update) and "Late-Breaking Clinical Trials". - Provides cutting-edge coverage of key topics such as proteomics and metabolomics, TAVR, diabetocardiology, and cardio-oncology. - Contains 1,850 high-quality illustrations, radiographic images, algorithms, and charts, and provides access to 215 videos called out with icons in the print version. - Highlights the latest AHA, ACC, and ESC guidelines to clearly summarize diagnostic criteria and clinical implications. - Provides tightly edited, focused content for quick, dependable reference. Flexible format options include either one or two volumes in print, as well as a searchable eBook with ongoing updates. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

The book describes the current state of digital radiology. It does not merely report single experiences, but readers will benefit from the systematic recommendations given. The book describes the development of digital radiology and networking from the late eighties up to now and outlines future perspectives. It gives readers an easy, nonetheless comprehensive overview and also how-to-do guidance for their own activities when implementing a digital radiology system. The book is a synthesis of the editors own 10 years' experience in planning and working with a fully digital, large-scale radiology department and the contributions of internationally well-known experts in the field of digital radiology.

As pediatric cardiology becomes more and more neonatal cardiology and even fetal cardiology, Neonatal Heart Disease by Robert M. Freedom, MO, Leland N. Benson, MD, and Jeffrey F. Smallhorn, MB is extraordinarily timely. Neonatal Heart Disease consists of 50 chapters by 25 distinguished contributors and is a worthy successor to The Neonate With Congenital Heart Disease by Richard D. Rowe, MD and his colleagues (1968 and 1981). The first ~dition of this book in 1968 established Richard D. Rowe, MD as the father of neonatal cardiology. As most pediatric cardiologists now know, Dick Rowe died on January 18, 1988 after a brief illness. It will therefore come as no surprise that the present volume is dedicated to this great and gentle man. Nor will it come as a surprise that I have been asked to devote this Foreword to Richard D. Rowe, MD, pioneering neonatal cardiologist and incomparable personal friend. What can one say about Dick Rowe? Well, there are at least two very different tales. There is Dick Rowe the public man -the factual account of Dick Rowe's achievements as a physician, educator, and research man - the Dick Rowe that virtually "everyone" knows. And then there is Dick Rowe the private man -the extraordinary human being who only his personal friends were privileged to know. I shall try to tell something of both stories. First, the public man - the factual account - is really quite amazing.

How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart? Are there important species differences in how contraction is regulated in the heart? How do the new molecular data fit together in understanding the heart beat? What goes wrong in ischemia, hypertrophy, and heart failure? This book paints a modern `portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). Excitation-Contraction Coupling and Cardiac Contractile Force – Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.