This report presents a cost analysis of Ethylene Dichloride (EDC) production from ethylene and hydrogen chloride using an oxychlorination process. The process examined is similar to INEOS process. This process involves an oxygen-based chlorination step, which is carried out in fixed-bed reactors. This report examines one-time costs associated with the construction of a United States-based plant and the continuing costs associated with the daily operation of such a plant. More specifically, it discusses: * Capital Investment, broken down by: - Total fixed capital required, divided in production unit (ISBL); infrastructure (OSBL) and contingency - Alternative perspective on the total fixed capital, divided in direct costs, indirect costs and contingency - Working capital and costs incurred during industrial plant commissioning and start-up * Production cost, broken down by: - Manufacturing variable costs (raw materials, utilities) - Manufacturing fixed costs (maintenance costs, operating charges, plant overhead, local taxes and insurance) - Depreciation and corporate overhead costs * Raw materials consumption, products generation and labor requirements * Process block flow diagram and description of industrial site installations (production unit and infrastructure) This report was developed based essentially on the following reference(s): US Patent 6465701, originally issued to EVC in 2002 (assigned to INEOS in 2008) Keywords: Ethene, 1,2-Dichloroethane, Inovyl, EVC, European Vinyls Corporation, Fixed-Bed Reactor

This practical how-to-do book deals with the design of sustainable chemical processes by means of systematic methods aided by computer simulation. Ample case studies illustrate generic creative issues, as well as the efficient use of simulation techniques, with each one standing for an important issue taken from practice. The didactic approach guides readers from basic knowledge to mastering complex flow-sheets, starting with chemistry and thermodynamics, via process synthesis, efficient use of energy and waste minimization, right up to plant-wide control and process dynamics. The simulation results are compared with flow-sheets and performance indices of actual industrial licensed processes, while the complete input data for all the case studies is also provided, allowing readers to reproduce the results with their own simulators. For everyone interested in the design of innovative chemical processes.

This report presents a cost analysis of Ethylene Dichloride (EDC) production from ethylene and hydrogen chloride using an oxychlorination process. The process examined is similar to OxyVinyls process. This process involves an oxygen-based chlorination step, which is carried out in fluidized-bed reactors. This report was developed based essentially on the following reference(s): (1) US Patent 7585806, issued to OxyVinyls in 2009 (2) US Patent 5292703, originally issued to The Geon Company (assigned to OxyVinyls in 1999) Keywords: Ethene, 1,2-Dichloroethane, Mitsui, Fluidized-Bed Reactor

Peptides play a decisive role in many physiological processes, whether as neurotransmitters, hormones or antibiotics. The rapid developments in peptide research over the past few decades make it almost impossible for newcomers to gain an overview. This means an easily comprehensible yet concise introduction is vital. This unique work covers all the important aspects of this wide-ranging field in one handy volume. On the basis of the fundamental chemical and structural properties of peptides, this reference runs the gamut from analysis, the occurrence and biological importance of peptides, via chemical, biochemical and genetic methods of peptide synthesis, right up to peptide libraries, peptide design and their role in drug research. Yet this book offers much more than a mere overview of the latest level of research. An encyclopedic appendix with valuable data on more than 500 biological relevant peptides and proteins, a comprehensive register and details of further literature references make this the ideal reference for all questions regarding peptide research. For newcomers and specialists alike. On the basis of the fundamental chemical and structural properties of peptides, this reference runs the gamut from analysis, the occurrence and biological importance of peptides.

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volumehas been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 275 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchers in all fields of life sciences. Key Features * Solid-phase peptide synthesis * Applications of peptides for structural and biological studies * Characterization of synthetic peptides

Chemistry of Peptide Synthesis is a complete overview of how peptides are synthesized and what techniques are likely to generate the most desirable reactions. Incorporating elements from the author's role of Career Investigator of the Medical Research Council of Canada and his extensive teaching career, the book emphasizes learning rather th

Most current state-of-the-art overview of this important class of compounds, encompassing many new and emerging applications The number of articles on organic azides continues to increase tremendously; on average, there are more than 1000 new publications a year Covers basic chemistry as well as state-of-the-art applications in life science and materials science World-ranked authors describe their own research in the wider context of azide chemistry Includes a chapter on safe synthesis and handling (azides can decompose explosively)

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. - Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patient - Explores the current generation of nanostructured 3D printed medical devices - Assesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals

This collection highlights materials research and innovations for a wide breadth of energy systems and technologies. The volume includes papers organized into the following sections:Energy and Environmental Issues in Materials Manufacturing and ProcessingMaterials in Clean PowerMaterials for Coal-Based PowerMaterials for Energy Conversion with Emphasis on SOFCMaterials for Gas TurbinesMaterials for Nuclear EnergyMaterials for Oil and Gas

This report presents a cost analysis of Ethylene Dichloride (EDC) production from ethylene and chlorine using a direct chlorination process. The process examined is similar to Vinnolit process. This process consists in a liquid-phase low temperature chlorination (LTC). This report examines one-time costs associated with the construction of a United States-based plant and the continuing costs associated with the daily operation of such a plant. More specifically, it discusses: * Capital Investment, broken down by: - Total fixed capital required, divided in production unit (ISBL); infrastructure (OSBL) and contingency - Alternative perspective on the total fixed capital, divided in direct costs, indirect costs and contingency - Working capital and costs incurred during industrial plant commissioning and start-up * Production cost, broken down by: - Manufacturing variable costs (raw materials, utilities) - Manufacturing fixed costs (maintenance costs, operating charges, plant overhead, local taxes and insurance) - Depreciation and corporate overhead costs * Raw materials consumption, products generation and labor requirements * Process block flow diagram and description of industrial site installations (production unit and infrastructure) Keywords: Ethene, 1,2-Dichloroethane, Vinnolit, Westlake