The 1993 regulation (Part 503 Rule) governing the land application of biosolids was established to protect public health and the environment from reasonably anticipated adverse effects. Included in the regulation are chemical pollutant limits, operational standards designed to reduce pathogens and the attraction of disease vectors, and management practices. This report from the Board on Environmental Studies and Toxicology evaluates the technical methods and approaches used by EPA to establish those standards and practices, focusing specifically on human health protection. The report examines improvements in risk-assessment practices and advances in the scientific database since promulgation of the regulation, and makes recommendations for addressing public health concerns, uncertainties, and data gaps about the technical basis of the biosolids standards.

This document is a compendium of scientifically valid and accepted methods that can be used to assess sediment quality and predict ecological impacts...the intent here is to provide the most useful overall measures or predictors of ecological impacts currently in use rather than procedures that may have limited application outside of a particular regulatory framework... parag The information provided in the compendium on the relative strengths and weaknesses of the different assessment methods can provide assistance in selecting the appropriate methods.

Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.

Biosolids (appropriately treated sewage sludge) can make an important contribution to sustainable environmental management, through the return of organic material, trace elements, moisture and nutrients to our soils. The Guidelines for Environmental Management: Biosolids Land Application enables this beneficial use of biosolids, by providing a management framework that ensures any chemical and microbiological risks are appropriately managed.