Endoscopy in Early Gastrointestinal Cancers, Volume 1: Diagnosis provides detailed information of the technique of novel endoscopic diagnostic tools including magnifying endoscopy, narrow band imaging system (NBI), autofluorescence endoscopy (AFI), endocytoscopy, FICE and confocal endomicroscopy. Carcinoma of the gastrointestinal tract remained a major health issue worldwide, which is, however notoriously difficult to treat. One of the major reasons for such a poor result is that these cancers are diagnosed at advanced stage. There is a recent increase in the number of gastrointestinal cancers diagnosed at early stage. This is attributed to an increasing recognition of these early stage cancers through a recent development in the technology of endoscopy. This book on the endoscopic diagnosis of early GI neoplasia, containing lots of illustrations, artwork and numerous short video clips, serves as a bridge between the recent development in endoscopy and the knowledge of gastroenterologist, endoscopist and surgeons.

Since a number of mucosal digestive tract cancer detected has increased in recent years with an advance of endoscopic instruments, endoscopic treatment of digestive tract cancer is widely spread in Japan but not in other countries. Minute cancers seem to have own characteristic mucosal signs compared with benign lesions. Therefore, strategies, those are different in Japan from other countries, of endoscopic diagnosis are very important. The cancer institute hospital of JFCR (Japan foundation of cancer research) is one of the top institutions which do the best endoscopic treatment in Japan. This book is expected to be the first valuable atlas in which the abundant experiences of this hospital offer beautiful photographs of minute cancers without any scars of biopsies which change aspects of original lesions. This book also offer pictures of magnifying endoscopy using NBI (Narrow Band Imaging) and pathological findings.

Table 1 Cancer is the second most common cause of death in Americans (see www.cdc.gov). Colorectal cancer kills more Incidence and Mortality of the Five Most Common Gastrointestinal Malignancies Americans than any other malignancy except for lung cancer. The incidences and mortalities of the major gastrointestinal a a Site Incidence Mortality (GI) malignancies are shown in Table 1. Taken as a group, the five most common GI malignancies account for more cancers Colorectum 53.9 21.6 and more cancer deaths than for any other site. Pancreas 11.1 10.6 Stomach 9.1 4.9 Flexible endoscopy has given physicians unprecedented Liver/intrahepatic bile ducts 6.2 4.4 access to the GI tract. The ability to endoscopically visu- Esophagus 4.5 4.3 alize, biopsy, and apply therapy has had implications for the management of all the major GI malignancies. Accepted Data from SEER database 1992–2002 (www.seer.cancer.gov). applications of endoscopy range from detection of mal- a Per 100,000.

This volume provides a concise overview of the most important and vital aspects of upper endoscopy. The text is specifically geared towards first-year GI fellows and novice endoscopists in order to help them rapidly assimilate the core concepts needed to perform upper endoscopy in the most important and most commonly encountered clinical situations. The book also covers the most important variations of normal anatomy and pathology and how to manage them. Key concepts covered include foreign body removal, diagnosis and management of upper GI bleeding, Barrett's Esophagus, evaluation and management of benign and malignant strictures of the esophagus, stomach, and duodenum, submucosal lesions, and evaluation of post operative upper GI anatomy. A plethora of high quality color illustrations and narrated online video clips illustrate major concepts in the book are also included. Written by experts in the field, Upper Endoscopy for GI Fellows is a valuable resource for new physicians just starting to perform upper endoscopy.

Since magnifying endoscopy of the stomach, or zoom gastroscopy, was first performed at the beginning of the 21st century , there have been numerous findings in the field worldwide. The author of this volume has developed a standardized magnifying endoscopy technique that enables endoscopists to constantly visualize the microanatomy (subepithelial capillaries and the epithelial structure) within the stomach. With this technology, it has become easy to obtain magnified endoscopic findings. Techniques differ, however, depending upon the endoscopist. Endoscopists around the world do not have a standardized magnifying endoscopy technique, which is mandatory for the scientific analysis of their findings. In addition, there is no logical explanation for how and which microanatomies are visualized by magnifying endoscopy with narrow-band imaging in the glandular epithelium of the stomach. This inconsistency results in considerable confusion among researchers and clinicians and a lack of terminology for the purposes of analysis. As magnifying endoscopy with narrow-band imaging (NBI) becomes more popular throughout the world, there is increased demand for a specialized reference book focused on this subject. The aims of the present volume, Zoom Gastroscopy: Magnifying Endoscopy in the Stomach, are manifold: (1) to illustrate the standard magnifying endoscopic technique that can visualize subepithelial mucosal microvessels as small as capillaries, the smallest unit of blood vessels in the human body, (2) to explain the optical phenomena and principles for NBI and its application to magnifying endoscopy, (3) to clarify which microanatomies are visualized by magnifying endoscopy with NBI and how this is achieved, and (4) to present a diagnostic system so called “VS classification system” for early gastric neoplasias. With a single author, the book consistently uses uniform anatomical terms to describe endoscopic findings, providing an essential reference for endoscopists in the world.

As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.

This important full-color atlas, written by pioneers in the field, provides complete, superbly illustrated coverage of both new and established techniques in GI endoscopy. Now fully updated with the newest interventional procedures.The book uses more than 500 high-definition watercolors derived from operative photographs which simulate the physician's cognitive visual experience while performing the procedures, and thus recreating both the look and feel of actual surgery. The accompanying text leads you step-by-step through each operation, and highlights both special tips and potential pitfalls. Thorough and usefully illustrated, this unique book will prove indispensable for all gastroenterologists and endoscopic surgeons.New topics include: Endoscopy mucosal en bloc resection for early gastrointestinal cancers, self-expandable metallic enteral stents, self-expandable metallic stents for Klatskin tumor, treatment of intraabdominal abscesses, and more.

Gastrointestinal endoscopy is now mainstream and the focus is nowchanging from developing new techniques to enhancing the efficiencyand quality of fundamental techniques. There are three elements tothis agenda: initial training, continuous quality improvement andpatient empowerment. For the first time, the book is accompanied by two CD-ROMs -featuring video and animation of how to perform the techniques. Thefirst CD-ROM covers the upper GI tract and consists of twosections: (1) the background to instruments and how to get set up,and (2) how to perform diagnostic techniques. The second CD-ROMcovers diagnostic and therapeutic procedures in colonoscopy. Cotton and Williams' book has evolved with each new edition toreflect developments in the field of endoscopy over the last 20years. This fifth edition draws on the vast experience of the authorsand heralds current changes in both endoscopy and publishing. The emerging 'back to basics' attitude of endoscopy opinionformers with regard to the teaching of endoscopy has resulted in amore focused table of contents specifically targeted at newcomersto this specialty.

This unique book is the first to focus on diagnostic and therapeutic endoscopy in gastrointestinal and pancreatico-biliary diseases. It provides an in-depth overview of the state of the art in diagnostic and therapeutic endoscopy of both the digestive tract and the pancreatico-biliary ductal system, and documents the latest innovations in the field. The first part of the book addresses advanced diagnostic and therapeutic endoscopy of the digestive tract, discussing bariatric endoscopic surgery, and the treatment of neoplasia and precancerous lesions of the upper and lower GI tract, motor disorders, GERD, strictures, fistulae and bleeding. The second part of the book is explores ERCP and EUS procedures, covering the diagnosis and therapy of biliary ductal system and pancreatic diseases. Each chapter includes an abundance of color images that document in detail the devices, operative techniques and outcomes. Written by leading internationally renowned experts, the book is a valuable resource for both specialists and residents in gastroenterology and surgery.

Esophageal cancer causes an estimated 386,000 deaths worldwide and is the sixth most common cause of death for men. The background characteristics of esophageal cancer treatment are markedly different between Asian and Western countries, however. In tumor histology, squamous cell carcinoma associated with smoking and alcohol consumption is overwhelmingly prevalent in Asia, whereas adenocarcinoma associated with Barrett’s metaplasia is markedly prevalent in the West. In Asia, especially in Japan, the key persons who play important roles in the management of esophageal cancer patients are surgeons; in the West those roles are filled by medical and radiation oncologists as well as surgeons. The philosophy of surgeons regarding cancer surgery varies from locoregional to local tumor control, particularly in focusing on lymph node dissection. Physicians’ approach to surgical adjuvant therapy differs, therefore, between Asia and the West. Considering these East–West differences in esophageal cancer treatment, the currently available results of Western evidence should not be considered directly applicable to esophageal cancer in Asia. In this book, the authors discuss the knowledge base in Japan in terms of treatment of esophageal squamous cell carcinoma. Since this volume contains a wide spectrum of current information and addresses topics surrounding the treatment of patients with esophageal squamous cell carcinoma, it is highly relevant to Asian physicians and researchers as well as to their counterparts in the West.