Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices covers the modern micro and nanotechnologies used for diagnosis, drug delivery, and theranostics using micro, nano, and implantable systems. In-depth coverage of all aspects of disease treatment is included. In addition, the book covers cutting-edge research and technology that will help readers gain knowledge of novel approaches and their applications to improve drug/agent specificity for diagnosis and efficient disease treatment. It is a comprehensive guide for medical specialists, the pharmaceutical-industry, and academic researchers discussing the impact of nanotechnology on diagnosis, drug delivery, and theranostics. - Gives readers working in immunology, drug delivery, and medicine a greater awareness on how novel nanotechnology orientated methods can help improve treatment - Provides readers with backgrounds in nanotechnology, chemistry, and materials science an understanding on how nanotechnology is used in immunology and drug delivery - Includes focused coverage of the use of nanodevices in diagnostics, therapeutics, and theranostics not offered by other books

Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. - Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage - Explains how nanomaterials can be manipulated to create more effective drug treatments - Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments

Nanotechnology is a multidisciplinary field that is revolutionizing the way we detect and treat damage to the human body. Nanomedicine applies nanotechnology to highly specific medical interventions for the prevention, diagnosis, and treatment of diseases. They are increasingly being used to overcome biological barriers in the body to improve the way we deliver compounds to specific tissues and organs. In particular, nanomedicines have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. Nanomedicines have demonstrated significant therapeutic advantages for a multitude of biomedical applications, however the clinical translation of these nanotechnology platforms has not progressed as quickly as the plethora of positive results would have suggested. Understanding the advances in nanomedicine to date and the challenges that still need to be overcome, will allow future research to improve on existing platforms and to address the current translational and regulatory limitations. This eBook “Advances and Challenges in Nanomedicine” has brought together experts in the fields of nanomedicine, nanotechnology, nanotoxicology, pharmaceutics, manufacturing, and translation to discuss the application of nanotechnology to drug delivery. This information is presented as original research, opinion, perspective, and review articles. The goal of this eBook is to generate collaborative discussion on the current status, general trends, challenges, strategies, and future direction of pharmaceutical nanotechnology, as well as highlight current and emerging nanoparticulate platforms with potential medical applications.

This book comprises state-of-the-art research results in the field of mechatronics and other closely related areas and that will be presented on occasion of the third “International Conference of Reliable Systems Engineering (ICoRSE 2023)” that will take place in Bucharest, Romania, between 07–08 September 2023. The first two ICoRSE editions brought together professors, Ph.D. students, and researchers in Europe, North America, and Asia, in countries such as: England, Albania, Austria, Bulgaria, Canada, Czech Republic, Germany, France, Italy, Portugal, Turkey, Ukraine, Uzbekistan, and Vietnam. In this year’s edition of the conference, we have benefitted from the inclusion in the scientific committee of the conference of professors in all of these countries, and we cover a wide variety of topics, such as: theoretical and applied mechanics; cyber-physical systems, robotics, smart bio-medical and bio-mechatronic systems, new and intelligent materials and structures, modelling and simulation in mechanics and mechatronics, smart mechatronic production and control system, optics, control systems, big data modelling, micro- and nanotechnology, automation, manufacturing optimization, and other. Since the book ́s chapters represent contributions of scholars who work in both state-funded institutions and in the business environment, they reflect a clear picture of the novelties attained in the leading-edge sciences that are in the scope of the conference. It is our belief that the book is useful to both students and researchers in all areas of engineering, who will each find at least one topic worthy of their interest in this work.

Emerging Nanotechnologies for Medical Applications focuses on both commercial and premarket tools and their applications in medicine. The book develops the concept of integrating different technologies along a hierarchical structure of biological systems and clarifies biomechanical interactions on different levels for the analysis of multiscale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it demonstrates how knowledge can be utilized in a range of areas, including the diagnosis and treatment of various human diseases, and in alternative energy production. This book is an important reference source for scientists and researchers involved in micro- and nano-engineering, bio-nanotechnology, biomedical engineering, nanomedicine, and industries involved with optical devices, computer simulation and pharmaceuticals. - Shows how nanotechnology is being used to improve outcomes in areas of cancer, tissue grafting, and printing drugs - Explores a variety of nanoengineering techniques used for biomedical applications, including for cardiovascular, renal and dental treatments - Assesses the major challenges of manufacturing nanomaterials-based medicines on an industrial scale

Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route. Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Nonparenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications. - Contains a comprehensive review of non-parenteral nanomedicines - Provides analysis of non-parenteral methods of nanomedicines including regulatory implications and future applications - Explores a wide range of promising approaches for non-parenteral drug delivery using the latest advancement in nanomedicine written by experts in industry and academia

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Human enhancement (HE) is considered one of the most profoundly impactful effects of the Fourth Industrial Revolution. This book presents the definition, theory, scope, and main challenges of HE from a health policy and healthcare systems perspective. It offers a comprehensive view of the consequences of human enhancement disrupting the status quo in health service delivery and social coherence. The book examines the latest achievements of HE, focusing on four forms of enhancement: cognitive, physical, mood and moral. These forms are supported by the list of specific technologies and techniques used for HE. The book identifies the current trends in HE's development and analyses the challenges that HE poses to health policy and healthcare systems. It discusses the legal and financial aspects of HE, including regulation and shows that the financing of HE goes far beyond the scope of universal health coverage, thus opening the door for private, voluntary insurance and/or out-of-pocket payments. This, in turn, leads towards growing inequalities, which may threaten social cohesion. Readers will receive a structured picture of the latest advances in HE and trends in the field, as well as a list of the challenges and problems that HE generates. The book offers a concise picture of HE for students and researchers across the political sciences, public health, public sector management, and sociology. It will also find an audience among healthcare managers, policymakers, and those who are interested in social change.

Emerging Applications of Nanoparticles and Architecture Nanostructures: Current Prospects and Future Trends discusses the most important current applications of nanoparticles and architecture nanostructures in a comprehensive, detailed manner. The book covers major applications of nanoparticles and architecture nanostructures, taking into account their unusual shapes and high surface areas. In particular, coverage is given to applications in aerospace, automotive, batteries, sensors, smart textile design, energy conversion, color imaging, printing, computer chips, medical implants, pharmacy, cosmetics, and more. In addition, the book discusses the future of research in these areas. This is a valuable reference for both materials scientists, chemical and mechanical engineers working both in R&D and academia who want to learn more on how nanoparticles and nanomaterials are commercially applied. - Provides an in-depth look at the properties of nanoparticles and architecture nanostructures in terms of their applicability for industrial uses - Analyzes the most recent advances and industrial applications of different types of nanoparticles and architecture nanostructures, taking into account their unusual structures and compositions - Identifies novel nanometric particles and architectures that are of particular value for applications and the techniques required to use them effectively