The definition of a healthcare system evolves continuously, becoming broader and more complex with each rendering. Healthcare systems can consist of many different elements, including but not limited to: access to comprehensive medical care, health promotion, disease prevention, institutional framework, financing schemes, government responsibility over health, etc. In light of its broad classification of healthcare, this book focuses on a wide spectrum of health-related issues ranging from risk factors for disease to medical treatment and possible frameworks for healthcare systems. Aging populations, increasing costs of healthcare, advancing technology, and challenges created by the COVID-19 pandemic require an innovative conceptual and methodological framework. By combining the experience and effort of researchers from a variety of fields including mathematics, medicine and economics, this book offers an interdisciplinary approach to studying health-related issues. It contributes to the existing literature by integrating the perspective of treatment with the economic determinants of health care outcomes, such as population density, access to financial resources and institutional frameworks. It also provides new evidence regarding the pharmaceutical industry including innovation, international trade and company performance. Contributors are: Sayansk Da Silva, Joe Feinglass, Scott W. Hegerty, Joseph E. Hibdon, Jr, Arkadiusz Michał Kowalski, Małgorzata Stefania Lewandowska, Dawid Majcherek, Ewelina Nojszewska, Izabela Pruchnicka-Grabias, Agata Sielska and Julian Smółka.

This book discusses significant research findings in the field of mathematical modelling, with particular emphasis on important applied-sciences, health, and social issues. It includes topics such as model on viral immunology, stochastic models for the dynamics of influenza, model describing the transmission of dengue, model for human papillomavirus (HPV) infection, prostate cancer model, realization of economic growth by goal programming, modelling of grazing periodic solutions in discontinuous systems, modelling of predation system, fractional epidemiological model for computer viruses, and nonlinear ecological models. A unique addition in the proposed areas of research and education, this book is a valuable resource for graduate students, researchers and educators associated with the study of mathematical modelling of health, social and applied-sciences issues. Readers interested in applied mathematics should also find this book valuable.

A model is a simplified representation of a real-world situation used to help answer a specific question. This book provides a look into the world of modelling with the focus on modelling in healthcare.--[from preface]

The construction of mathematical models is an essential scientific activity. Mathematics is associated with developments in science and engineering, but more recently mathematical modelling has been used to investigate complex systems that arise in other fields. This book demonstrates the application of mathematics to research topics in ecology and environmental science, health and medicine, phylogenetics and neural networks, theoretical chemistry, economics and management.

The problems of interrelation between human economics and natural environment include scientific, technical, economic, demographic, social, political and other aspects that are studied by scientists of many specialities. One of the important aspects in scientific study of environmental and ecological problems is the development of mathematical and computer tools for rational management of economics and environment. This book introduces a wide range of mathematical models in economics, ecology and environmental sciences to a general mathematical audience with no in-depth experience in this specific area. Areas covered are: controlled economic growth and technological development, world dynamics, environmental impact, resource extraction, air and water pollution propagation, ecological population dynamics and exploitation. A variety of known models are considered, from classical ones (Cobb Douglass production function, Leontief input-output analysis, Solow models of economic dynamics, Verhulst-Pearl and Lotka-Volterra models of population dynamics, and others) to the models of world dynamics and the models of water contamination propagation used after Chemobyl nuclear catastrophe. Special attention is given to modelling of hierarchical regional economic-ecological interaction and technological change in the context of environmental impact. Xlll XIV Construction of Mathematical Models ...

The main goal of this book is to present coherent mathematical models to describe an economic growth and related economic issues. The book is a continuation of the authors previous book Mathematical Dynamics of Economic Markets (9781594545283), which presented mathematical models of economic forces acting on the markets. In his previous book, the author described a system of ordinary differential equations, which connected together economic forces behind the products demand, supply and prices on the market. The author focuses on a specific aspect of how to modify the said system of ordinary differential equations, in order to describe the phenomenon of economic growth. In order to achieve clarity, the author restricted himself to economic processes arising on the markets of a single-product economy. Economic growth is presented as a result of savings and investment occurring on the markets. The markets participants withdraw part of the product from markets in the form of savings and use the withdrawn product in production in the form of an investment. The withdrawal drives the products supply on the market down while at the same time driving the products price up, which in turn drives the products demand down. When an impact of the products price increase exceeds an impact of the products demand decrease, economic growth occurs. Contrarily, one observes an economic decline in the opposite situation. The author looks into various aspects that savings and investment exert on the market. He in particular discusses the models that examine an economic growth in situations when savings and investment were done in the form of a one-time withdrawal of the product, constant-rate withdrawal of product, constant-accelerated withdrawal of product, and exponential withdrawal of product from the market. The author further examines an impact of four economic concepts on economic growth -- demand, supply, investment, and debt. He presents mathematical models exploring interconnections among these concepts and studies their mutual impacts on both economic growth and decline. He builds a mathematical model in order to verify a hypothesis that weak recovery after the financial crisis could be attributed to the decline of investments that were not compensated by the decrease of an interest rate. The author also looks into the phenomenon of economic crises and builds a few mathematical models. The models of four economic crises are considered. The first model concerns the last financial crisis where an author tried to explain how relatively small disturbances on financial markets had produced a large impact on the real economy. His conclusion is that fluctuations on connected markets amplify each other, which is known as the resonance phenomenon. The second model relates to the monetary part of Japanese economic policy known as Abenomics, where the price of Japanese bonds decreases and the yield increases. The author builds a mathematical model to investigate this phenomenon. The third model is about a secular stagnation hypothesis advanced by Lawrence Summers. The author complements his model of economic growth with the external supply of product to the market. He found that external supply provided with either constant rate or constant acceleration can cause a restricted or unrestricted economic decline, respectively. The fourth model is a model describing the four stages of the Greek economic crisis (before the Eurozone, before the Euro crisis, after the Euro crisis, and during the austerity period) and two potential recovery stages (with austere and benign economic transformations).

Human Papillomavirus: Proving and Using a Viral Cause for Cancer presents a steady and massive accumulation of evidence about the role of HPV and prevention of HPV-induced cancer, along with the role and personal commitment of many scientists of different backgrounds in establishing global relevance. This exercise involved years of personal commitment to proving or disproving an idea that aroused initial skepticism, and that still has difficult implications for some. It remains one of the big successes of medicine that exploited both established medical science dating back to the nineteenth century and new molecular genetic science during a time of transition in medicine. - Presents a comprehensive, up-to-date review of the role of HPV in cancer from those involved in its study - Includes the way evidence on the role and utility of HPV based prevention has been accumulated over almost 40 years - Gives a series of vignettes of individual scientists involved in the development of the science of HPV and cancer at different stages and their experiences and reasons for involvement

Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected.

In this new book the author, Alexi Krouglov, examines real business cycles, financial markets, and economic growth with various mathematical models. Real business cycles are examined with three different models: one product and one supplier, one product and two suppliers, and n-products with n-suppliers. Financial markets are examined with more complex models because more complex topics, such as inflation and the stock market, are involved. Economic growth is examined through mathematical models that are specifically concerned with trade and arbitrage.

Employing a practical, "learn by doing" approach, this first-rate text fosters the development of the skills beyond the pure mathematics needed to set up and manipulate mathematical models. The author draws on a diversity of fields — including science, engineering, and operations research — to provide over 100 reality-based examples. Students learn from the examples by applying mathematical methods to formulate, analyze, and criticize models. Extensive documentation, consisting of over 150 references, supplements the models, encouraging further research on models of particular interest. The lively and accessible text requires only minimal scientific background. Designed for senior college or beginning graduate-level students, it assumes only elementary calculus and basic probability theory for the first part, and ordinary differential equations and continuous probability for the second section. All problems require students to study and create models, encouraging their active participation rather than a mechanical approach. Beyond the classroom, this volume will prove interesting and rewarding to anyone concerned with the development of mathematical models or the application of modeling to problem solving in a wide array of applications.