A broad overview of the interaction of DNA with surfactants and polymers Due to the potential benefits of biotechnology, interest in the interaction between DNA and surfactants and polymers has become increasingly significant. Now, DNA Interactions with Polymers and Surfactants provides an extensive, up-to-date overview of the subject, giving readers a basis for understanding the factors leading to complexation between DNA and different cosolutes, including metal ions, polyelectrolytes, spermine, spermidine, surfactants and lipids, and proteins. Topical coverage includes: Polyelectrolytes, physico-chemical aspects and biological significance Solution behavior of nucleic acids Single DNA molecules: compaction and decompaction Interaction of DNA with surfactants and cationic polymers Interactions of histones with DNA DNA-DNA interactions The hydration of DNA-amphiphile complexes DNA-surfactant/lipid complexes at liquid interfaces DNA and DNA-surfactant complexes at solid surfaces The role of correlation forces for DNA-cosolute interactions Simulations of polyions Cross-linked DNA gels and gel particles DNA as an amphiphilic polymer Lipid-DNA interactions Covering both theoretical and practical aspects of the subject, DNA Interactions with Polymers and Surfactants is an ideal resource for chemists and biochemists working in gene and DNA delivery research in industry and academia, as well as for cell biologists, chemical engineers, molecular biologists, and development biologists in the pharmaceutical industry.

"DNA Interactions with Polymers and Surfactants" provides a broad overview of the interaction of DNA with cosolutes in both bulk solution and at interfaces. It provides the basis for understanding the factors leading to complexation between DNA and different cosolutes as well as DNA adsorption at different interfaces, and covers DNA-cosolute interactions including simple metal ions, polyelectrolytes, spermine, spermidine, surfactants and lipids, and proteins. Theoretical information such as important correlations forces, are addressed, as well has more practical aspects, such as the biological significance of the interactions such as with chromatin and transfection.

Many industrial formulations such as detergents, paints, foodstuff and cosmetics contain both surfactants and polymers and their interaction govern many of the properties. This book is unique in that it discusses the solution chemistry of both surfactants and polymers and also the interactions between the two. The book, which is based on successful courses given by the authors since 1992, is a revised and extended version of the first edition that became a market success with six reprints since 1998. Surfactants and Polymers in Aqueous Solution is broad in scope, providing both theoretical insights and practical help for those active in the area. This book contains a thorough discussion of surfactant types and gives information of main routes of preparation. A chapter on novel surfactants has been included in the new edition. Physicochemical phenomena such as self-assembly in solution, adsorption, gel formation and foaming are discussed in detail. Particular attention is paid to the solution behaviour of surfactants and polymers containing polyoxyethylene chains. Surface active polymers are presented and their interaction with surfactants is a core topic of the book. Protein-surfactant interaction is also important and a new chapter deals with this issue. Microemulsions are treated in depth and several important application such as detergency and their use as media for chemical reactions are presented. Emulsions and the choice of emulsifier is discussed in some detail. The new edition also contains chapters on rheology and wetting. Surfactants and Polymers in Aqueous Solution is aimed at those dealing with surface chemistry research at universities and with surfactant formulation in industry.

"Chronicles recent advances in our knowledge of polymer-surfactant systems, combining authoritative reviews of new experimental methods, instrumentation, and applications with fundamental discussions of classical methodologies and surveys of specific properties."

Colloids show great potential in a wide variety of applications, including drug delivery and medical imaging, and the design and fabrication of colloid systems has attracted considerable interest in the research community. Colloids in Biotechnology describes developments in the field of biotechnological applications in the past decade and bridges t

Surfactant research explores the forces responsible for surfactant assembly and the critical industrial, medical, and personal applications, including viscosity control, microelectronics, drug stabilization, drug delivery, cosmetics, enhanced oil recovery, and foods. Surfactant Science and Technology: Retrospects and Prospects, "a Festschrift in honor of Dr. Kash Mittal," provides a broad perspective with chapters contributed by leaders in the fields of surfactant-based physical, organic, and materials chemistries. Many of the authors participated in a special symposium in Melbourne, Australia, honoring Kash Mittal’s 100th edited book at the 18th Surfactants in Solution (SIS) meeting. Each chapter provides an overview of a specific research area, with discussions on past, present, and future directions. The book is divided into six parts. Part I reviews the evolution of theoretical models for surfactant self-assembly, and introduces a model for interpreting ion-specific effects on aggregate properties. Part II focuses on interactions of surfactant solutions with solid supports; uses contact angles to understand hydrophobic/hydrophilic changes in a lipid layer; uses surface tension to understand molecular arrangements at interfaces; reviews spreading phenomena; discusses pattern formation on solid surfaces; and applies tensiometry to probe flavor components of espresso. Part III discusses novel DNA-based materials, multifunctional poly(amino acid)s–based graft polymers for drug delivery, and polymeric surfactants for stabilizing suspensions and emulsions. Part IV introduces farm-based biosurfactants from natural products and "greener" biosurfactants from bacteria. Part V explores lyotropic liquid crystals and their applications in triggered drug release; microemulsion properties and controlled drug release; the role of hydrotopes in formulations and in enhancing solubilization in liquid crystals; the potential of ionic liquids to generate tunable and selective reaction media; and provides an overview of stimuli-responsive surfactants. Focusing on emulsions, Part VI reviews the design of emulsion properties for various commercial applications, the role of surfactants in the oil and gas industries, and surfactant mechanisms for soil removal via microemulsions and emulsification.

It is the belief of the editors of this book that the recognition of block copolymers as being amphiphilic molecules and sharing common features with other well-studied amphiphiles will prove beneficial to both the surfactant and the polymer communities. An aim of this book is to bridge the two communities and cross-fertilise the different fields. To this end, leading researchers in the field of amphiphilic block copolymer self-assembly, some having a background in surfactant chemistry, and others with polymer physics roots, have agreed to join forces and contribute to this book.The book consists of four entities. The first part discusses theoretical considerations behind the block copolymer self-assembly in solution and in the melt. The second part provides case studies of self-assembly in different classes of block copolymers (e.g., polyethers, polyelectrolytes) and in different environments (e.g., in water, in non-aqueous solvents, or in the absence of solvents). The third part presents experimental tools, ranging from static (e.g., small angle neutron scattering) to dynamic (e.g., rheology), which can prove valuable in the characterization of block copolymer self-assemblies. The fourth part offers a sampling of current applications of block copolymers in, e.g., formulations, pharmaceutics, and separations, applications which are based on the unique self-assembly properties of block copolymers.

Les interactions entre l'ADN et une série de molécules amphiphiles ont étés étudiés en combinant des techniques spectroscopiques anisotropes (absorption fluorescence) et polarisées (dichroïsme circulaire, dépolarisation de fluorescence). Les résultats obtenus ont été ensuite analysés en utilisant un modele de docking moléculaire et indiquent que l'utilisation de la sonde fluorescente bromure d'éthidium pour étudier les interactions entre ADN et amphiphiles est bien plus complexe que ce postulé actuellement dans la littérature. L'utilisation d'une nouvelle sonde, le composé Hoechst 33258, est proposé.

The renewed and increasing interest in lipid self-assembly, phase behaviour and interfacial properties can be related to both a much improved insight in biological systems and the applications of lipids in food and pharmaceutical industry; in the latter, the development of drug delivery systems based on lipids has become in focus. Amphiphilic systems comprise lipids, surfactants as well as different types of polymers, including block and graft copolymers. Research on biological amphiphiles has often been conducted separate from research on synthetic ones. However, in recent years a very fruitful convergence between the two fields has evolved. These new perspectives on fundamental research and applications of lipids are discussed in these proceedings from an international symposium on "Lipid and Polymer Lipid-systems", October 2000 in Chia Laguna in Italy - a joint undertaking of Prof. Maura Monduzzi at Cagliari University, Italy and Camurus Lipid Research Foundation, Lund, Sweden.