A behind-the-scenes look at the most lucrative discipline within biotechnology Bioinformatics represents a new area of opportunity for investors and industry participants. Companies are spending billions on the potentially lucrative products that will come from bioinformatics. This book looks at what companies like Merck, Glaxo SmithKline Beecham, and Celera, and hospitals are doing to maneuver themselves to leadership positions in this area. Filled with in-depth insights and surprising revelations, Digital Code of Life examines the personalities who have brought bioinformatics to life and explores the commercial applications and investment opportunities of the most lucrative discipline within genomics. Glyn Moody (London, UK) has published numerous articles in Wired magazine. He is the author of the critically acclaimed book Rebel Code.

For sample chapters, a video interview with David Hillis, and more information, visit www.whfreeman.com/hillispreview. Sinauer Associates and W.H. Freeman are proud to introduce Principles of Life. Written in the spirit of the reform movement that is reinvigorating the introductory majors course, Principles of Life cuts through the thicket of excessive detail and factual minutiae to focus on what matters most in the study of biology today. Students explore the most essential biological ideas and information in the context of the field’s defining experiments, and are actively engaged in analyzing research data. The result is a textbook that is hundreds of pages shorter (and significantly less expensive) than the current majors introductory books.

This is a detailed history of one of the most important and dramatic episodes in modern science, recounted from the novel vantage point of the dawn of the information age and its impact on representations of nature, heredity, and society. Drawing on archives, published sources, and interviews, the author situates work on the genetic code (1953-70) within the history of life science, the rise of communication technosciences (cybernetics, information theory, and computers), the intersection of molecular biology with cryptanalysis and linguistics, and the social history of postwar Europe and the United States. Kay draws out the historical specificity in the process by which the central biological problem of DNA-based protein synthesis came to be metaphorically represented as an information code and a writing technology—and consequently as a “book of life.” This molecular writing and reading is part of the cultural production of the Nuclear Age, its power amplified by the centuries-old theistic resonance of the “book of life” metaphor. Yet, as the author points out, these are just metaphors: analogies, not ontologies. Necessary and productive as they have been, they have their epistemological limitations. Deploying analyses of language, cryptology, and information theory, the author persuasively argues that, technically speaking, the genetic code is not a code, DNA is not a language, and the genome is not an information system (objections voiced by experts as early as the 1950s). Thus her historical reconstruction and analyses also serve as a critique of the new genomic biopower. Genomic textuality has become a fact of life, a metaphor literalized, she claims, as human genome projects promise new levels of control over life through the meta-level of information: control of the word (the DNA sequences) and its editing and rewriting. But the author shows how the humbling limits of these scriptural metaphors also pose a challenge to the textual and material mastery of the genomic “book of life.”

In Life Code: The New Rules for Winning in the Real World, six-time New York Times #1 best-selling author Dr. Phil McGraw abandons traditional thinking and tells you the ugly truth about the users, abusers, and overall “bad guys” we all have in our lives. He also reveals the secrets of how they think and how they get to and exploit you and those you love. You’ll gain incredible insight into these negative people, which he refers to as BAITERs (Backstabbers, Abusers, Imposters, Takers, Exploiters, Reckless), and you’ll gain the tools to protect yourself from their assaults. Dr. Phil's new book gives you the “Evil Eight” identifiers so you can see them coming from a mile away, as well as their “Secret Playbook,” which contains the “Nefarious 15” tactics they use to exploit you and take what is yours mentally, physically, socially and professionally. Life Code then focuses on you and your playbook, which contains the “Sweet 16” tactics for winning in the real world. Edgy, controversial and sometimes irreverent, Dr. Phil again abandons convention to prepare you to claim what you deserve and claim it now. You take flying lessons to learn to fly, swimming lessons to learn to swim, and singing lessons to learn to sing. So, why not take winning lessons to learn to win?

“Venter instills awe for biology as it is, and as it might become in our hands.” —Publishers Weekly On May 20, 2010, headlines around the world announced one of the most extraordinary accomplishments in modern science: the creation of the world’s first synthetic lifeform. In Life at the Speed of Light, scientist J. Craig Venter, best known for sequencing the human genome, shares the dramatic account of how he led a team of researchers in this pioneering effort in synthetic genomics—and how that work will have a profound impact on our existence in the years to come. This is a fascinating and authoritative study that provides readers an opportunity to ponder afresh the age-old question “What is life?” at the dawn of a new era of biological engineering.

The Gene Book: Explorations in the Code of Life is designed to introduce undergraduate college students to foundational concepts in genetics. The text provides in-depth coverage of the essential principles of genetics, from Mendel to molecular gene therapy, and reads like a story, guiding readers through each of these areas in an interesting, engaging, and enlightening way. Milestone scientific discoveries introduce conceptual topics in each of the 10 chapters. The significance of each genetics paradigm is reinforced by the meaningful research context in which it is placed, whether the focus is single gene inheritance of disorders such as PKU and cystic fibrosis, or more complex genetic phenomena. Chromosomes, cell division, and cytogenetic disorders, including Down Syndrome and leukemia, are presented in a riveting historical context. In addition, the principles of molecular genetics are a major focus of this book. Students learn about the double helix, DNA replication, gene expression, mutation, natural selection, genomics, and the tools of molecular DNA analysis. Approachable and effective, The Gene Book is a highly readable comprehensive text on genetics principles designed to highlight essential concepts that make up their very core. The text is well suited to undergraduate genetics courses and can also be used as a primer for more advanced undergraduate and graduate courses in medical or molecular genetics.

Provided by Horace Freeland Judson, author of the bestselling Eighth Day of Creation. The book's broad and balanced coverage and the expertise of its contributors make The Code of Codes the most comprehensive and compelling exploration available on this history-making project.

The never-more-necessary return of one of our most vital and eloquent voices on technology and culture, the author of the seminal Close to the Machine The last twenty years have brought us the rise of the internet, the development of artificial intelligence, the ubiquity of once unimaginably powerful computers, and the thorough transformation of our economy and society. Through it all, Ellen Ullman lived and worked inside that rising culture of technology, and in Life in Code she tells the continuing story of the changes it wrought with a unique, expert perspective. When Ellen Ullman moved to San Francisco in the early 1970s and went on to become a computer programmer, she was joining a small, idealistic, and almost exclusively male cadre that aspired to genuinely change the world. In 1997 Ullman wrote Close to the Machine, the now classic and still definitive account of life as a coder at the birth of what would be a sweeping technological, cultural, and financial revolution. Twenty years later, the story Ullman recounts is neither one of unbridled triumph nor a nostalgic denial of progress. It is necessarily the story of digital technology’s loss of innocence as it entered the cultural mainstream, and it is a personal reckoning with all that has changed, and so much that hasn’t. Life in Code is an essential text toward our understanding of the last twenty years—and the next twenty.

"Dr. Taylor Hartman offers an incisive system for improving your understanding of yourself and others and strengthening your day-to-day relationships. In first The People Code and The Character Code, Dr. Hartman introduces the Color Code Personality Profile, explaining why people do what they do by identifying four basic personality types and showing you how to use "color profiles" to cultivate rich and balanced character and relationships. All people... possess one of four driving "core motives," classified by color: Red ("power wielders"), Blue ("do-gooders"), White ("peacekeepers"), and Yellow ("fun lovers"). Once you understand your color code--and the color codes of others--you can analyze your own innate personality and use that knowledge to balance your relationships, both personal and professional"--from back cover.

The authors examine software from a spatial perspective, analyzing the dyadic relationship of software & space. The production of space, they argue, is increasingly dependent on code, & code is written to produce space.