In this issue of MRI Clinics, guest editors Drs. Reza Forghani and Ashok Srinivasan bring their considerable expertise to the topic of Demyelinating and Inflammatory Lesions of the Brain and Spine. Top experts in the field provide multiple articles on multiple sclerosis, as well as articles on bacterial, fungal, and viral infections of the brain and spine. - Contains 10 relevant, practice-oriented topics including demyelinating disease: NMO spectrum disorders and variants; toxic and drug-related white matter diseases of the brain and spine; bacterial and viral infectious diseases of the brain; bacterial and viral infectious diseases of the spine; multiple sclerosis: clinical update and clinically-oriented radiologic reporting; basic science of neuroinflammation and involvement of the inflammatory response in disorders of the nervous system; and more. - Provides in-depth clinical reviews on demyelinating and inflammatory lesions of the brain and spine, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of MRI Clinics, guest editors Drs. Max Wintermark and Ananth Madhuranthakam bring their considerable expertise to the topic of MR Perfusion. Top experts in the field discuss all three MR perfusion techniques (DSC, DCE, and ASL), as well as provide separate articles on evaluation of gliomas, breast cancer, musculoskeletal, prostate, and heart. - Contains 13 relevant, practice-oriented topics including perfusion imaging for brain tumors; dynamic susceptibility contrast (DSC) MR perfusion; arterial spin labelling (ASL) MR perfusion; MR perfusion imaging of prostate; dynamic contrast-enhanced (DCE) MR perfusion; MR perfusion imaging for breast cancer; and more. - Provides in-depth clinical reviews on MR perfusion, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of MRI Clinics, guest editors Drs. Camilo Jaime Cobos and Jungwhan J. Choi bring their considerable expertise to the topic of Fetal MRI. Top experts in the field offer a primer on this timely topic, with coverage of how to use fetal MRI, safety and quality issues, and the use of fetal MRI for individual body systems: head and neck, cardiac, gastrointestinal, genitourinary, spine, and skeletal malformations. - Contains 13 relevant, practice-oriented topics including quality and safety in fetal MRI; how to perform fetal MRI; fetal cardiac MRI; fetal gastrointestinal MRI; fetal skeletal dysplasias; imaging the abnormal placenta; complicated twin pregnancies and fetoscopic interventions; and more. - Provides in-depth clinical reviews on fetal MRI, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of MRI Clinics, guest editors Drs. Dheeraj Gandhi and Graeme F. Woodworth bring their considerable expertise to the topic of MR-Guided Focused Ultrasound. Top experts in the field cover a broad range of topics on the use of magnetic resonance-guided focused ultrasound (MRgFUS) for brain tumors, breast tumors, musculoskeletal applications, movement disorders, prostate conditions, and neurodegenerative disorders. - Contains 12 relevant, practice-oriented topics MRgFUS for neurodegenerative disorders, including Alzheimer's disease; the use of MRgFUS for movement disorders; MRgFUS for musculoskeletal applications; MRgFUS for breast tumors; future directions in MRgFUS; and more. - Provides in-depth clinical reviews on MR-guided focused ultrasound, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of MRI Clinics, guest editor Dr. Jenny T. Bencardino brings her considerable expertise to the topic of MR Imaging of the Hip. Top experts in the field provide a comprehensive look at major issues with the hip, beginning with an update on imaging the hip and including articles on anatomy, artificial Intelligence, young adults, stress injuries, impingement syndromes, and many more. - Contains 15 relevant, practice-oriented topics including an update on MRI techniques of the hip; artificial intelligence applications in MRI of the hip; diagnostic evaluations of stress injuries of the hip using MRI; MRI of the hip: infectious and inflammatory conditions; MRI of tumors and tumor-like conditions of the hip; and more. - Provides in-depth clinical reviews on MR Imaging of the Hip, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of MRI Clinics, guest editors Prof. Minerva Becker and Dr. Valentino Garibotto bring their considerable expertise to the topic of Clinical Value of Hybrid PET/MRI. Combined PET/MRI has significant advantages over other imaging methods—a lesser radiation dose, excellent soft tissue contrast, numerous radiotracers available for PET, and more, making it a good choice for diagnostics and staging, as well as surgical planning. In this issue, top experts explore these advantages and more, helping you make the most of this relatively new dual-imaging modality in your practice. - Contains 10 relevant, practice-oriented topics including breast imaging using PET/MRI; abdominal imaging using PET/MRI; brain imaging using PET/MRI; musculoskeletal imaging using PET/MRI; PET/MRI in radiation therapy planning; pediatric imaging using PET/MRI; and more. - Provides in-depth clinical reviews on the clinical value of hybrid PET/MRI, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue, guest editors bring their considerable expertise to this important topic. - Contains 11 practice-oriented topics including MR angiography: non-contrast acquisition techniques; MR angiography of aortic diseases; MR angiography of extracranial carotid disease; 4D flow MRI: technique and advances; MRI for intracranial vessel wall imaging; and more. - Provides in-depth clinical reviews on MR angiography, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue of Magnetic Resonance Imaging Clinics, guest editors Drs. John Conklin and Michael Lev bring their considerable expertise to the topic of MR in the Emergency Room. Top experts in the field cover key topics such as penile and scrotal trauma, thoracic emergencies, biliary obstruction, GI/GU emergencies, abdominal and pelvic emergencies in the pregnant patient, pediatric emergencies, and more. - Contains 14 relevant, practice-oriented topics including acute stroke; intracranial trauma, hemorrhage, and other non-stroke vascular emergencies; spinal emergencies; head and neck emergencies; musculoskeletal trauma and infection; and more. - Provides in-depth clinical reviews on MR in the emergency room, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This book provides cutting-edge information on the epidemiology, etiopathogenesis, clinical manifestations, diagnostic procedures and treatment approaches for the main white matter (WM) disorders of the central nervous system (CNS). WM lesions are associated with many neurological conditions, and with aging. The diagnostic work-up of neurological diseases characterized by the presence of these lesions has changed dramatically over the past few years. This is mainly due on the one hand to the discovery of specific pathogenetic factors in some of these conditions, and on the order to the optimized use of diagnostic tools. All of this has resulted in new diagnostic algorithms, and in the identification of new neurological conditions. The book offers neurologists essential guidance in the diagnosis and treatment of the most frequent WM conditions, promoting their correct and cost-saving diagnosis and management. By integrating neurological, laboratory and imaging concepts with the demands of accurate diagnosis, this reference guide provides a state-of-the-art overview of the current state of knowledge on these conditions, as well as practical guidelines for their diagnosis and treatment.

Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.