Deep learning has already achieved remarkable results in many fields. Now it’s making waves throughout the sciences broadly and the life sciences in particular. This practical book teaches developers and scientists how to use deep learning for genomics, chemistry, biophysics, microscopy, medical analysis, and other fields. Ideal for practicing developers and scientists ready to apply their skills to scientific applications such as biology, genetics, and drug discovery, this book introduces several deep network primitives. You’ll follow a case study on the problem of designing new therapeutics that ties together physics, chemistry, biology, and medicine—an example that represents one of science’s greatest challenges. Learn the basics of performing machine learning on molecular data Understand why deep learning is a powerful tool for genetics and genomics Apply deep learning to understand biophysical systems Get a brief introduction to machine learning with DeepChem Use deep learning to analyze microscopic images Analyze medical scans using deep learning techniques Learn about variational autoencoders and generative adversarial networks Interpret what your model is doing and how it’s working

Explore all the tools and templates needed for data scientists to drive success in their biotechnology careers with this comprehensive guide Key FeaturesLearn the applications of machine learning in biotechnology and life science sectorsDiscover exciting real-world applications of deep learning and natural language processingUnderstand the general process of deploying models to cloud platforms such as AWS and GCPBook Description The booming fields of biotechnology and life sciences have seen drastic changes over the last few years. With competition growing in every corner, companies around the globe are looking to data-driven methods such as machine learning to optimize processes and reduce costs. This book helps lab scientists, engineers, and managers to develop a data scientist's mindset by taking a hands-on approach to learning about the applications of machine learning to increase productivity and efficiency in no time. You'll start with a crash course in Python, SQL, and data science to develop and tune sophisticated models from scratch to automate processes and make predictions in the biotechnology and life sciences domain. As you advance, the book covers a number of advanced techniques in machine learning, deep learning, and natural language processing using real-world data. By the end of this machine learning book, you'll be able to build and deploy your own machine learning models to automate processes and make predictions using AWS and GCP. What you will learnGet started with Python programming and Structured Query Language (SQL)Develop a machine learning predictive model from scratch using PythonFine-tune deep learning models to optimize their performance for various tasksFind out how to deploy, evaluate, and monitor a model in the cloudUnderstand how to apply advanced techniques to real-world dataDiscover how to use key deep learning methods such as LSTMs and transformersWho this book is for This book is for data scientists and scientific professionals looking to transcend to the biotechnology domain. Scientific professionals who are already established within the pharmaceutical and biotechnology sectors will find this book useful. A basic understanding of Python programming and beginner-level background in data science conjunction is needed to get the most out of this book.

Principles and Labs for Deep Learning provides the knowledge and techniques needed to help readers design and develop deep learning models. Deep Learning techniques are introduced through theory, comprehensively illustrated, explained through the TensorFlow source code examples, and analyzed through the visualization of results. The structured methods and labs provided by Dr. Huang and Dr. Le enable readers to become proficient in TensorFlow to build deep Convolutional Neural Networks (CNNs) through custom APIs, high-level Keras APIs, Keras Applications, and TensorFlow Hub. Each chapter has one corresponding Lab with step-by-step instruction to help the reader practice and accomplish a specific learning outcome. Deep Learning has been successfully applied in diverse fields such as computer vision, audio processing, robotics, natural language processing, bioinformatics and chemistry. Because of the huge scope of knowledge in Deep Learning, a lot of time is required to understand and deploy useful, working applications, hence the importance of this new resource. Both theory lessons and experiments are included in each chapter to introduce the techniques and provide source code examples to practice using them. All Labs for this book are placed on GitHub to facilitate the download. The book is written based on the assumption that the reader knows basic Python for programming and basic Machine Learning. - Introduces readers to the usefulness of neural networks and Deep Learning methods - Provides readers with in-depth understanding of the architecture and operation of Deep Convolutional Neural Networks - Demonstrates the visualization needed for designing neural networks - Provides readers with an in-depth understanding of regression problems, binary classification problems, multi-category classification problems, Variational Auto-Encoder, Generative Adversarial Network, and Object detection

This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.

This book focuses on the fundamentals of deep learning along with reporting on the current state-of-art research on deep learning. In addition, it provides an insight of deep neural networks in action with illustrative coding examples. Deep learning is a new area of machine learning research which has been introduced with the objective of moving ML closer to one of its original goals, i.e. artificial intelligence. Deep learning was developed as an ML approach to deal with complex input-output mappings. While traditional methods successfully solve problems where final value is a simple function of input data, deep learning techniques are able to capture composite relations between non-immediately related fields, for example between air pressure recordings and English words, millions of pixels and textual description, brand-related news and future stock prices and almost all real world problems. Deep learning is a class of nature inspired machine learning algorithms that uses a cascade of multiple layers of nonlinear processing units for feature extraction and transformation. Each successive layer uses the output from the previous layer as input. The learning may be supervised (e.g. classification) and/or unsupervised (e.g. pattern analysis) manners. These algorithms learn multiple levels of representations that correspond to different levels of abstraction by resorting to some form of gradient descent for training via backpropagation. Layers that have been used in deep learning include hidden layers of an artificial neural network and sets of propositional formulas. They may also include latent variables organized layer-wise in deep generative models such as the nodes in deep belief networks and deep boltzmann machines. Deep learning is part of state-of-the-art systems in various disciplines, particularly computer vision, automatic speech recognition (ASR) and human action recognition.

Demystifying Big Data, Machine Learning, and Deep Learning for Healthcare Analytics presents the changing world of data utilization, especially in clinical healthcare. Various techniques, methodologies, and algorithms are presented in this book to organize data in a structured manner that will assist physicians in the care of patients and help biomedical engineers and computer scientists understand the impact of these techniques on healthcare analytics. The book is divided into two parts: Part 1 covers big data aspects such as healthcare decision support systems and analytics-related topics. Part 2 focuses on the current frameworks and applications of deep learning and machine learning, and provides an outlook on future directions of research and development. The entire book takes a case study approach, providing a wealth of real-world case studies in the application chapters to act as a foundational reference for biomedical engineers, computer scientists, healthcare researchers, and clinicians. - Provides a comprehensive reference for biomedical engineers, computer scientists, advanced industry practitioners, researchers, and clinicians to understand and develop healthcare analytics using advanced tools and technologies - Includes in-depth illustrations of advanced techniques via dataset samples, statistical tables, and graphs with algorithms and computational methods for developing new applications in healthcare informatics - Unique case study approach provides readers with insights for practical clinical implementation

In the best science classrooms, teachers see learning through the eyes of their students, and students view themselves as explorers. But with so many instructional approaches to choose from—inquiry, laboratory, project-based learning, discovery learning—which is most effective for student success? In Visible Learning for Science, the authors reveal that it’s not which strategy, but when, and plot a vital K-12 framework for choosing the right approach at the right time, depending on where students are within the three phases of learning: surface, deep, and transfer. Synthesizing state-of-the-art science instruction and assessment with over fifteen years of John Hattie’s cornerstone educational research, this framework for maximum learning spans the range of topics in the life and physical sciences. Employing classroom examples from all grade levels, the authors empower teachers to plan, develop, and implement high-impact instruction for each phase of the learning cycle: Surface learning: when, through precise approaches, students explore science concepts and skills that give way to a deeper exploration of scientific inquiry. Deep learning: when students engage with data and evidence to uncover relationships between concepts—students think metacognitively, and use knowledge to plan, investigate, and articulate generalizations about scientific connections. Transfer learning: when students apply knowledge of scientific principles, processes, and relationships to novel contexts, and are able to discern and innovate to solve complex problems. Visible Learning for Science opens the door to maximum-impact science teaching, so that students demonstrate more than a year’s worth of learning for a year spent in school.

Deep Learning for Medical Applications with Unique Data informs readers about the most recent deep learning-based medical applications in which only unique data gathered in real cases are used. The book provides examples of how deep learning can be used in different problem areas and frameworks in both clinical and research settings, including medical image analysis, medical image registration, time series analysis, medical data synthesis, drug discovery, and pre-processing operations. The volume discusses not only positive findings, but also negative ones obtained by deep learning techniques, including the use of newly developed deep learning techniques rarely reported in the existing literature. The book excludes research works with ready data sets and includes only unique data use to better understand the state of deep learning in real-world cases, along with the feedback and user experiences from physicians and medical staff for applied deep learning-based solutions. Other applications presented in the book include hybrid solutions with deep learning support, disease diagnosis with deep learning focusing on rare diseases and cancer, patient care and treatment, genomics research, as well as research on robotics and autonomous systems. - Introduces deep learning, demonstrating concepts for a wide variety of medical applications using unique data, excluding research with ready datasets - Encompasses a wide variety of biomedical applications, including unsupervised learning, natural language processing, pattern recognition, image and video processing and disease diagnosis - Provides a robust set of methods that will help readers appropriately and judiciously use the most suitable deep learning techniques for their applications

Rigorous treatment of the theory of deep learning from first principles, with applications to beautiful problems in the natural sciences.

Deep learning is often viewed as the exclusive domain of math PhDs and big tech companies. But as this hands-on guide demonstrates, programmers comfortable with Python can achieve impressive results in deep learning with little math background, small amounts of data, and minimal code. How? With fastai, the first library to provide a consistent interface to the most frequently used deep learning applications. Authors Jeremy Howard and Sylvain Gugger, the creators of fastai, show you how to train a model on a wide range of tasks using fastai and PyTorch. You’ll also dive progressively further into deep learning theory to gain a complete understanding of the algorithms behind the scenes. Train models in computer vision, natural language processing, tabular data, and collaborative filtering Learn the latest deep learning techniques that matter most in practice Improve accuracy, speed, and reliability by understanding how deep learning models work Discover how to turn your models into web applications Implement deep learning algorithms from scratch Consider the ethical implications of your work Gain insight from the foreword by PyTorch cofounder, Soumith Chintala