Cytotoxic Cells
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Author |
: Kenneth Murphy |
Publisher |
: Garland Science |
Total Pages |
: |
Release |
: 2010-06-22 |
ISBN-10 |
: 0815344570 |
ISBN-13 |
: 9780815344575 |
Rating |
: 4/5 (70 Downloads) |
Synopsis Janeway's Immunobiology by : Kenneth Murphy
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author |
: |
Publisher |
: |
Total Pages |
: 0 |
Release |
: 2002 |
ISBN-10 |
: 0815332181 |
ISBN-13 |
: 9780815332183 |
Rating |
: 4/5 (81 Downloads) |
Synopsis Molecular Biology of the Cell by :
Author |
: Michael T. Lotze |
Publisher |
: Academic Press |
Total Pages |
: 709 |
Release |
: 2009-11-12 |
ISBN-10 |
: 9780080919294 |
ISBN-13 |
: 0080919294 |
Rating |
: 4/5 (94 Downloads) |
Synopsis Natural Killer Cells by : Michael T. Lotze
Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses. The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body. The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine. - Provides a broad, detailed coverage of the biology and interactions of NK cells for students, fellows, scientists, and practitioners - Includes figures, histologic sections, and illustrations of the ontogeny of NK cells
Author |
: Jonathan Soboloff |
Publisher |
: CRC Press |
Total Pages |
: 258 |
Release |
: 2017-03-27 |
ISBN-10 |
: 9781498705097 |
ISBN-13 |
: 149870509X |
Rating |
: 4/5 (97 Downloads) |
Synopsis Signaling Mechanisms Regulating T Cell Diversity and Function by : Jonathan Soboloff
T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
Author |
: Jacques Zimmer |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 425 |
Release |
: 2010-01-12 |
ISBN-10 |
: 9783642023095 |
ISBN-13 |
: 3642023096 |
Rating |
: 4/5 (95 Downloads) |
Synopsis Natural Killer Cells by : Jacques Zimmer
Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad range of NK cell-related topics, including those that are not frequently reviewed, e.g. NK cells and allergy or NK cells and skin diseases.
Author |
: SITKOVSKY |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 528 |
Release |
: 2012-12-06 |
ISBN-10 |
: 9781468468144 |
ISBN-13 |
: 1468468146 |
Rating |
: 4/5 (44 Downloads) |
Synopsis Cytotoxic Cells: Recognition, Effector Function, Generation, and Methods by : SITKOVSKY
Our motivation for putting together this book was the need for a single source reference that could be used as an introduction to cell-mediated cytotoxicity for newcomers to this field, such as students and fellows beginning work in our laboratories. At present no such book is available, and we felt that it would be useful as a teaching tool and as a way of conveying our enthusiasm about recent progress in the cytotoxicity field to our colleagues in allied areas. It was with some hesitation that we approached our colleagues with the proposal for this book, and we were pleased to find them very supportive of the idea and willing to participate. We thought it important to broaden the scope of the book to include historical, molecular, cell biological, and clinical aspects of cell-mediated cytotoxicity. To our knowledge this is the first book on cell-mediated cytotoxicity with such a broad scope. Historically, studies on cellular cytotoxicity were part of cellular immunology from its origin. One development of tremendous import was the advent of the 51 Cr assay, which allowed this arm of the immune response to be measured easily and quantitatively. Thus, a readout of this effector pathway is available within a few hours; other immune effector functions can take days or even longer to assay, and the assays are often less quantitative.
Author |
: Eric Vivier |
Publisher |
: Springer |
Total Pages |
: 251 |
Release |
: 2016-02-15 |
ISBN-10 |
: 9783319239163 |
ISBN-13 |
: 3319239163 |
Rating |
: 4/5 (63 Downloads) |
Synopsis Natural Killer Cells by : Eric Vivier
To celebrate the 40th anniversary of the discovery of Natural Killer (NK) cells, this volume focuses on the recent advances in our understanding of NK cell development and differentiation and their acquisition of functional properties, as well as the latest models for NK-cell analysis in mice and applications in clinical medicine. NK cells have travelled a circuitous path from their initial description as ‘spontaneous killers’ (for some simply an experimental artifact) to being a bona fide subset of innate lymphoid cells with a complementary mode of action in immune defense and an important mediator of immune reactivity in health and disease. Together, these reviews provide a timely and concise picture of the evolution of NK cells as essential agents in immunity and as potent weapons against disease. This book offers an appealing and insightful resource for scientists and clinicians.
Author |
: Kitty Verhoeckx |
Publisher |
: Springer |
Total Pages |
: 341 |
Release |
: 2015-04-29 |
ISBN-10 |
: 9783319161044 |
ISBN-13 |
: 3319161040 |
Rating |
: 4/5 (44 Downloads) |
Synopsis The Impact of Food Bioactives on Health by : Kitty Verhoeckx
“Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.
Author |
: A. L. Notkins |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 418 |
Release |
: 2012-12-06 |
ISBN-10 |
: 9781461252504 |
ISBN-13 |
: 1461252504 |
Rating |
: 4/5 (04 Downloads) |
Synopsis Concepts in Viral Pathogenesis by : A. L. Notkins
The current proliferation of scientific information makes it difficult for even the most diligent reader to keep up with the latest developments in his/her own field, let alone other areas of interest. Review articles are one solution, but they too have become so voluminous and detailed that they often defeat the purpose for which they were intended. We have attempted to ease this problem by using a different format. In this volume on Concepts in Viral Pathogenesis, we have assembled a series of mini-reviews/editorials, 1,000 to 2,000 words in length. Each is a pithy distil lation of the state-of-the-art with emphasis on current thinking and unifying concepts rather than a compendium of the literature. The 53 articles, all written by active workers in their respective fields, are organized systemati cally so that the book will provide busy investigators, teachers and students of up-to-date information in a very brief and easily read a conceptual core able form. In addition, the authors have attempted to identify unresolved problems and point to future directions.
Author |
: M. V. Sitkovskii |
Publisher |
: Lippincott Williams & Wilkins |
Total Pages |
: 508 |
Release |
: 2000 |
ISBN-10 |
: UOM:39015048516770 |
ISBN-13 |
: |
Rating |
: 4/5 (70 Downloads) |
Synopsis Cytotoxic Cells by : M. V. Sitkovskii
This volume synthesizes recent groundbreaking advances in our knowledge of the molecular mechanisms, biological roles, and medical applications of cytotoxic lymphocytes. Leading investigators examine current concepts on the recognition of antigen by T-cell receptors; the molecules mediating target recognition by natural killer cells; the intracellular signalling cascades triggered by these molecules; and the effector molecules that damage target cells. The contributors present new insights into the roles of cytotoxic lymphocytes in vivo in immune regulation, autoimmunity, antiviral resistance, and tumor surveillance. Several chapters explore potential medical applications of cytotoxic lymphocytes, including vaccines, tumor therapy, and treatment of HIV infection.