Globally, pregnancy and childbirth are periods of high morbidity and mortality for women. The key to reducing the risks associated with pregnancy and childbirth is early recognition and provision of high quality care. The aims of critical care issues’ management are broad, the need to address the defects in conceiving followed by early recognition, prevention, and management of preterm births and threatened miscarriages along with studying the essential factors responsible for the same. Infertility has been ranked as one of the greatest sources of stress in a person’s life, comparable to a somatic disease such as cancer and ranked second to that involving the death of a family member or divorce. The role of stress and immunomodulation as a causative factor for infertility has been studied in greater details in recent times due to the changing lifestyles and a relevant discussion has been provided by the author with specific considerations in the Indian clinical settings. Endometriosis is the disease of the millennium, a sticky, perplexing and unconquerable pathology, which has remained an enigma. With increased awareness about endometriosis, improved methods of diagnosis like transvaginal sonography, liberal use of laparoscopy and more frequent evaluation of CA 125, the incidence of endometriosis is rising and thus, a clear understanding of the condition with application of the various advances in the recognition and also the new management protocols being followed, are the need of the day for the practitioners across the country. The polycystic ovary syndrome (PCOS), which features amenorrhea, hirsutism, and obesity, which was initially considered a reproductive and cosmetic concern of young women of reproductive age group, has more recently been recognized to have metabolic and cardiovascular associations that make it of major consequence for women of all age groups worldwide. Keeping in mind the requirements of the society, the practitioners need to update themselves on the current approach and the wide variety of choices now available. This book encompasses the rich experience of the specialists in India who are among the stalwarts in this field.

Critical Issues in Obstetrics and Gynecology - ECAB - E-Book

Critical Issues and Diabetes - ECAB - E-Book

Informed choice is the right of an individual. Gynecologists have immense responsibility and a unique opportunity to guide their patients through the various milestones/changes in their life by good counseling—menarche, sexuality, pregnancy, pelvic operations, and menopause. Adolescents should be taught about safe sex practices, premarital counseling, and contraception. Preconception counseling is also important in the identification of risk factors, disease states, and potential teratogens in the pregnancy. The availability of first-trimester prenatal diagnosis and the advent of presymptomatic diagnosis by DNA analysis have created increasing opportunities to avoid disorders characterized by early death, severe disease, or irreparable mental retardation, for example, periconceptional maternal folic acid supplementation has now been shown to provide high protective effect against neural tube defects. Similarly, certain maternal diseases, including diabetes, lupus, and myotonic muscular dystrophy, impose potential maternal, fetal, neonatal, and other complications. The preconception visits provide important opportunities for intervention, avoidance, or prevention in these cases. The patients’ ethnicity and medical and genetic family history are key elements in their evaluation, whereas patients with prolonged infertility of unknown cause or recurrent spontaneous abortion may have a 3–10% risk of a parental chromosome abnormality, which may also require chromosome analysis, as do their spouses.

Steroids are an important class of biomolecules with diverse roles and functions. Besides being important as structural and signaling molecules, these molecules hold promise against numerous disorders, including cardiovascular conditions, cancer, inflammation, and autoimmune disorders. Many investigations have demonstrated that steroidal frameworks may provide lipid solubility, receptor selectivity, or membrane binding properties to non-steroidal pharmacophores. However, the therapeutic use of steroids can be dangerous when they're used incorrectly. Additionally, misconceptions about steroids among athletes or recreational users can lead to steroid abuse and poor health outcomes. Steroids and their MedicinalPotential discusses the classification, distribution, biosynthesis, chemical synthesis, and semi-synthesis of different steroids. The medicinal potential of each class is exhaustively discussed in different chapters. The latest advances and developments in steroid-based drug discovery are also discussed thoroughly. The book aims to address general questions and concerns about steroids, providing readers with a useful resource on the subject. Key Features -Provides comprehensive coverage on all aspects of steroids including steroid chemistry, biochemistry, medicinal potential, drug discovery, and advances in target-binding interactions of steroid-based drugs -Includes chapters dedicated to anabolic steroids and their abuse -Designed as an accessible source of information for understanding steroidal drugs with structured chapters-Includes references for advanced readers.

Part of a new series on reproductive medicine, this book is a complete guide to assisted reproductive technology (ART). Divided into 39 chapters, the book covers all aspects of ART, providing clinicians with a step by step guide through the processes. The text covers ovarian stimulation, embryo transfer, imaging, hormone analysis, endometrial receptivity, surgical procedures and much more. Many different causes of infertility and their management through ART are described in detail. The book presents the latest advances in the field and each chapter includes key points and references for further reading. Clinical photographs, diagrams and tables further enhance the comprehensive text. Other titles in the series include: Practical Guide in Infertility, Practical Guide in Reproductive Surgery and Practical Guide in Andrology and Embryology. Key points Comprehensive guide to assisted reproductive technology Part of new series on reproductive medicine Covers numerous ART procedures for management of infertility Chapters include key points and detailed references for further reading

Winner of the 2017 Jabuti Book Prize The Zika virus is devastating lives and communities. Children across the Americas are being born with severe disabilities because of it. Yet during the desolating outbreak, Brazil played host to both the Olympics and the FIFA World Cup, leading many to suspect that the true impact of the virus has been subject to a cover-up of international proportions. Beginning in the northeast, where the devastation has been most felt, professor of bioethics and award-winning documentary filmmaker Debora Diniz travels across Brazil tracing the virus’s origin and spread. Along the journey she meets a host of fearless families, doctors and scientists uncovering the virus’s impact on local communities. In doing so Diniz paints a vivid picture of the Zika epidemic, exposing the Brazilian government’s complicity in allowing the virus to spread while championing the efforts of local doctors and mothers who, working together, are raising awareness of the virus and fighting for the rights of children affected by Zika.

This volume examines why hospitals collaborate with each other and with other health care actors across borders in Europe. Cross-border hospital collaboration is not a new phenomenon but began to receive increased attention in the first decade of the 21st century in the context of European debates on patient mobility, the impact of European Union (EU) integration on national health systems and the particular situation of border regions. In this context, the role of health care providers stands out: while physically anchored in the health system that funds and regulates them, hospitals in border regions often witness or initiate cross-border movements of patients and health professionals.

A practical textbook for clinicians seeking advice on either how to manage a patient or how to perform a procedure within maternal-foetal medicine. This third edition strengthens the evidence base of each chapter with a clear section on evidence supporting different management options.

This text covers all aspects of the current diagnosis and treatment of acute cholecystitis. Different diagnostic tests are discussed as well as the preoperative evaluation needed to initiate treatment. Other sections include the management of acute cholecystitis in the critically ill and elderly patients, recent advances in operative strategies that have further altered the treatment of acute cholecystitis, and the utilization of routine intraoperative cholangiography and its relative merits. Primarily intended for general surgeons and residents training in general surgery, Acute Cholecystitis will also serve as a comprehensive reference material for other health care providers, including primary care providers, mid-level nurse practitioners, emergency room physicians and medical students.