The global response to the COVID-19 pandemic is the greatest science policy failure in a generation. We knew this was coming. Warnings about the threat of a new pandemic have been made repeatedly since the 1980s and it was clear in January that a dangerous new virus was causing a devastating human tragedy in China. And yet the world ignored the warnings. Why? In this short and hard-hitting book, Richard Horton, editor of the medical journal The Lancet, scrutinizes the actions that governments around the world took – and failed to take – as the virus spread from its origins in Wuhan to the global pandemic that it is today. He shows that many Western governments and their scientific advisors made assumptions about the virus and its lethality that turned out to be mistaken. Valuable time was lost while the virus spread unchecked, leaving health systems unprepared for the avalanche of infections that followed. Drawing on his own scientific and medical expertise, Horton outlines the measures that need to be put in place, at both national and international levels, to prevent this kind of catastrophe from happening again. Were supposed to be living in an era where human beings have become the dominant influence on the environment, but COVID-19 has revealed the fragility of our societies and the speed with which our systems can come crashing down. We need to learn the lessons of this pandemic and we need to learn them fast because the next pandemic may arrive sooner than we think.

COVID Chaos is a book about the 2019 SARS-CoV-2 Pandemic that was written real time, spanning the time from March 31, 2020 through December 31, 2021, by two Emeritus Professors of Infectious Diseases (Adult - RJS, Pediatrics - JSA). RJS's and JSA's careers began with the HIV pandemic, involved collaboration with the 2009 Influenza pandemic, and now are finishing up with the Coronavirus pandemic. The authors have broad experience with outbreaks, from the local level (RJS had career long responsibilities for controlling outbreaks at medical school hospitals and worked taking care of COVID-19 patients during the pandemic), all the way up to the pandemic level (JSA wrote a book about the 2009 Influenza pandemic and has worked with the WHO for the past 10 years.The aim of the book is to give the reader some insight into the global impact of the SARS-CoV-2 outbreak during the first two years, from multiple perspectives (patient, healthcare provider, global citizen, public health, economic, geopolitical). An attempt was also made to understand how SARS-CoV-2 caused disease, both its pathogenesis at the individual patient level, and globally, as to how it was so successful at causing a pandemic and how it compares with other organisms capable of causing outbreaks, epidemics and pandemics. It is written to be of interest to anyone who likes to read and wants to know more about what happened during the COVID-19 pandemic and why.COVID Chaos was written by two infectious disease physicians, who each have over 35 years of experience caring for patients with a large variety of infectious diseases. Additionally, both did research in understanding the pathogenesis of infectious diseases, and collectively have many years of experience handling outbreaks at the local level, have been involved with guideline documents making recommendations for reducing infections at the national level, and have global experience managing international infectious diseases.The book begins with three first person accounts from physicians involved in COVID-19 care during the early pandemic, when it was overwhelming hospitals.It then tracks its course from Wuhan, China, to other parts of the world, while comparing and contrasting public health interventions, both at the hospital and local community level, all the way up to country level.The book attempts to understand the broad spectrum of COVID-19 disease, both clinically and pathophysiologically, as well as its global collateral damage. It explores in depth SARS-CoV-2 vaccine development, testing and the geopolitical problems with vaccine deployment, and attempts to understand the origin of SARS-CoV-2 and its place in the pantheon of other organisms causing pandemics.The book concludes with some late breaking pandemic events at the end of 2021 (Omicron variant, etc.) and a global photo essay about the pandemic.

Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

Instant #1 New York Times and Wall Street Journal bestseller From the Washington Post journalists Yasmeen Abutaleb and Damian Paletta—the definitive account of the Trump administration’s tragic mismanagement of the COVID-19 pandemic, and the chaos, incompetence, and craven politicization that has led to more than a half million American deaths and counting. Since the day Donald Trump was elected, his critics warned that an unexpected crisis would test the former reality-television host—and they predicted that the president would prove unable to meet the moment. In 2020, that crisis came to pass, with the outcomes more devastating and consequential than anyone dared to imagine. Nightmare Scenario is the complete story of Donald Trump’s handling—and mishandling—of the COVID-19 catastrophe, during the period of January 2020 up to Election Day that year. Yasmeen Abutaleb and Damian Paletta take us deep inside the White House, from the Situation Room to the Oval Office, to show how the members of the administration launched an all-out war against the health agencies, doctors, and scientific communities, all in their futile attempts to wish away the worst global pandemic in a century. From the initial discovery of this new coronavirus, President Trump refused to take responsibility, disputed the recommendations of his own pandemic task force, claimed the virus would “just disappear,” mocked advocates for safe-health practices, and encouraged his base and the entire GOP to ignore or rescind public health safety measures. Abutaleb and Paletta reveal the numerous times officials tried to dissuade Trump from following his worst impulses as he defied recommendations from the experts and even members of his own administration. And they show how the petty backstabbing and rivalries among cabinet members, staff, and aides created a toxic environment of blame, sycophancy, and political pressure that did profound damage to the public health institutions that Americans needed the most during this time. Even after an outbreak in the fall that swept through the White House and infected Trump himself, he remained defiant in his approach to the virus, very likely costing him his own reelection. Based on exhaustive reporting and hundreds of hours of interviews from inside the disaster zone at all levels of authority, Nightmare Scenario is a riveting account of how the United States government failed its people as never before, a tragedy whose devastating aftershocks will linger and be felt by generations to come.

The hottest trend spotter in North America reveals powerful strategies for thriving in any economic climate. Did you know that Hewlett?Packard, Disney, Hyatt, MTV, CNN, Microsoft, Burger King, and GE all started during periods of economic recession? Periods of uncertainty fuel tremendous opportunity, but the deck gets reshuffled and the rules of the game get changed. EXPLOITING CHAOS is the ultimate business survival guide for all those looking to change the world. Topics include: SPARKING A REVOLUTION, TREND: HUNTING, ADAPTIVE INNOVATION and INFECTIOUS MESSAGING.

A guide to the pandemic economy: essential reading about the long-term implications of our current crisis. The COVID-19 pandemic has unleashed a firehose of information (much of it wrong) and an avalanche of opinions (many of them ill-founded). Most of us are so distracted by the everyday awfulness that we don't see the broader issues in play. In this book, economist Joshua Gans steps back from the short-term chaos to take a clear and systematic look at how economic choices are being made in response to COVID-19. He shows that containing the virus and pausing the economy—without letting businesses fail and people lose their jobs—are the necessary first steps.

NATIONAL BESTSELLER • With stark poignancy and political dispassion Tightrope addresses the crisis in working-class America while focusing on solutions to mend a half century of governmental failure. This must-read book from the authors of Half the Sky “shows how we can and must do better” (Katie Couric). "A deft and uniquely credible exploration of rural America, and of other left-behind pockets of our country. One of the most important books I've read on the state of our disunion."—Tara Westover, author of Educated Drawing us deep into an “other America,” the authors tell this story, in part, through the lives of some of the people with whom Kristof grew up, in rural Yamhill, Oregon. It’s an area that prospered for much of the twentieth century but has been devastated in the last few decades as blue-collar jobs disappeared. About a quarter of the children on Kristof’s old school bus died in adulthood from drugs, alcohol, suicide, or reckless accidents. While these particular stories unfolded in one corner of the country, they are representative of many places the authors write about, ranging from the Dakotas and Oklahoma to New York and Virginia. With their superb, nuanced reportage, Kristof and WuDunn have given us a book that is both riveting and impossible to ignore.

Looking for information about the key elements in the ongoing war against the COVID-19 pandemic? Confused and upset by all the conflicting information from many sources? This book from genomics industry expert Dale Yuzuki breaks down diagnostics, therapeutics and vaccines from an insider's perspective written for the non-expert. You will get the needed context to put all the biomedical advances continually reported on into perspective, and feel reassured that all the activity that is going on "behind the scenes" will finally put an end to the pandemic that is upending the lives of everyone. Curious to see how this war will ultimately end?

The explosive, behind-the-scenes story of Donald Trump’s high-stakes confrontation with Beijing, from an award-winning Washington Post columnist and peerless observer of the U.S.–China relationship There was no calm before the storm. Donald Trump’s surprise electoral victory shattered the fragile understanding between Washington and Beijing, putting the most important relationship of the twenty-first century in the hands of a novice who had bitterly attacked China from the campaign trail. Almost as soon as he entered office, Trump brought to a boil the long-simmering rivalry between the two countries, while also striking up a “friendship” with Chinese president Xi Jinping — whose manipulations of his American counterpart would undermine the White House’s already disjointed response to the historic challenge of a rising China. All the while, Trump’s own officials fought to steer U.S. policy from within. By the time the COVID-19 pandemic erupted in Wuhan, Trump’s love-hate relationship with Xi had sparked a trade war, while Xi’s aggression had pushed the world to the brink of a new Cold War. But their quarrel had also forced a long-overdue reckoning within the United States over China’s audacious foreign-influence operations, horrific human rights abuses, and creeping digital despotism. Ironically, this awakening was one of the biggest foreign-policy victories of Trump’s fractious term in office. ​Filled with shocking revelations drawn from Josh Rogin’s unparalleled access to top U.S. officials from the White House and deep within the country’s foreign policy machine, Chaos Under Heaven reveals an administration at war with itself during perhaps our most urgent hour.