Since the middle of the Sixties, new types of formulation for biologically active com pounds have been developed, which have been introduced into the literature under the term Controlled Release Formulations (CRF). Stimulated by results from former and successful pharmaceutical research, which was engaged in the production of prepa rations with protracted effects (introduction onto the market in the year 1952 of D amphetamine in the form of pellets, coated to varying degrees with fats and waxes) 1), experiments were carried out to transfer the prolongation of effectiveness to pesticidal substances also, by means of a depot formulation. Initial work was concerned with the production of protective coatings for sonar systems in marine ecosystems. By means of antifouling paints or rubber coatings containing tri-n-butyl-tin oxide (TBTO), the growth of marine organisms on sonar domes, buoys and hulls in the water could be effectively prevented 2. 3). Controlled release formUlations of pesticides are defined as depot systems which continuously release their toxic constituents into the environment over a specified period of time (usually months to years) 4). According to this definition, such formu lations can be successfully employed where a chronic exposure to biologically active compounds is required over a longer period. The following hypothetical example is intended to illustrate this 5). In Fig. 1, the duration of activity of a non-persistent pesticide with a loss rate under environmental conditions of t1/2 = 15 days, is graphically illustrated.

Highlighting means of reducing toxicity, increasing efficacy, lessening environmental impact, and facilitating product development, this work covers up-to-date advances in pesticide delivery technologies. It evaluates pesticide formulations and their use in mixtures that reduce physical incompatibilities in spray tanks and biological anatagonism in the field.

Public concern is being increasingly directed to pesticides and their residues in ground and surface waters. Water - one of the necessities of life - has to be kept clean for man and the environment. Part I and II of this book describe in an authoritative way all aspects of modern analysis of pesticides in water by the consequent use of hyphenated techniques like GC-AED or HPLC-MS.

Public concern is being increasingly directed to pesticides and their residues in ground and surface waters. Water - one of the necessities of life - has to be kept clean for man and the environment. Part I and II of this book describe in an authoritative way all aspects of modern analysis of pesticides in water by the consequent use of hyphenated techniques like GC-AED or HPLC-MS.

Pesticides in ground, surface and drinking water are a hot topic under continuing discussion. This complete and authoritative volume draws together information on all key issues on the fate and behaviour of pesticides in water systems. The scope of the practice-oriented contributions and the eminence of contributing authors make it an important source for researchers and practitioners in the plant protection and crop science field.

Chemicals inhibiting the biosynthesis of branched-chain amino acids form a new and promising class of herbicides. This volume discusses in an authoritative way recent developments in this field and covers important aspects of these potent herbicides (synthesis, structure-activity, mode of action, selectivity, weed resistance, metabolism).

Authored by an integrated committee of plant and animal scientists, this review of newer molecular genetic techniques and traditional research methods is presented as a compilation of high-reward opportunities for agricultural research. Directed to the Agricultural Research Service and the agricultural research community at large, the volume discusses biosciences research in genetic engineering, animal science, plant science, and plant diseases and insect pests. An optimal climate for productive research is discussed.

Over the past 30 years one alarming trend is the emergence of plant species resistant to agrochemicals (e.g. insecticides, herbicides, fungicides). Considering the fact that these pesticides are crucial to human health and to food, feed and fiber production, impressive research was carried out during the last decade to understand the mechanisms of resistance development. This volume reviews the latest results and examines the implications of these findings for delaying or avoiding resistance in plants to agrochemicals.