This issue of Neurosurgery Clinics, edited by Drs. Shahid Nimjee and Russell Lonser, will cover Coagulation and Hematology in Neurological Surgery. Topics include Biology of coagulation and coagulopathy; Evaluation of the coagulation in the neurosurgery patient; Genetics of hyper- and hypo-coagulable states; Anticoagulants: pharmacokinetics, mechanisms of action and indications; Use of antiplatelet agents in the neurosurgical patient; Common conditions requiring long-term anti-coagulation in the neurosurgical patient; Reversal of systemic and antiplatelet anticoagulants; Intraoperative blood and factor replacement neurosurgery; Management of Intraoperative coagulopathy; Deep vein thrombosis prophylaxis in the neurosurgical patient; Postoperative anticoagulation after neurological surgery; Management of venous sinus thrombosis; Management of acute ischemic thrombosis; and Management of intracranial hemorrhage the anticoagulated patient.

This issue of Neurosurgery Clinics, edited by Alejandro A. Rabinstein, will focus on Neurocritical Care. Topics will include Anoxic-Ischemic Brain Injury, Practical Approach to Posttraumatic Intracranial Hypertension According to Pathophysiologic Reasoning, Management of Traumatic Brain Injury: An Update, Cortical Spreading Depression and Ischemia in Neurocritical Patients, Targeted Temperature Management in Brain-Injured Patients, Herpes Virus Encephalitis in Adults: Current Knowledge and Old Myths, Primary Acute Neuromuscular Respiratory Failure, Intensive Care Unit–Acquired Weakness, Recent Advances in the Acute Management of Intracerebral Hemorrhage, New Developments in Refractory Status Epilepticus, Acute Cardiac Complications in Critical Brain Disease, Nosocomial Infections in the Neurointensive Care Unit, Neurologic Complications of Solid Organ Transplantation, and Shared Decision Making in Neurocritical Care.

This issue of Surgical Oncology Clinics of North America focuses on Biliary Tract and Primary Liver Tumors and is edited by Dr. T. Clark Gamblin. Articles will include: Biliary Tract and Primary Liver Tumors; Biliary Tract and Primary Liver Tumors: Who, What and Why?; Imaging Updates for Biliary Tract or Primary Liver Tumors; Endoscopic and Percutaneous Approaches to Treat of Biliary Tract and Primary Liver Tumors: Controversies and Advances; Intrahepatic Cholangiocarcinoma: Strategies and Options; Surgical Considerations of Hilar Cholangiocarcinoma; Gall Bladder Cancer: Managing the Incidental Diagnosis; Approaches and Outcomes to Distal Cholangiocarcinoma; Evolving Surgical Options of Hepatocellular Carcinoma; Staging of Biliary and Primary Liver Tumors: Current Reccomendations and Workup; Systemic and Targeted Therapy for Biliary Tract Tumors and Primary Liver Tumors; Regional Chemotherapy for Biliary Tract and Primary Liver Cancer; Role of Radioembolization for Biliary Tract and Primary Liver Cancer; Inoperable Biliary Tract and Primary Liver Tumors: Palliative Treatment Options; Expanding the Surgical Pool for Hepatic Resection to Treat Biliary and Primary Liver Tumors; and more!

This issue of Neurosurgery Clinics, guest edited by Drs. Guy McKhann and Hugues Duffau, with consulting editors Russell R. Lonser and Daniel K. Resnick, will focus on Low-Grade Glioma. Topics includes, but are not limited to, Epidemiology and Molecular Epidemiology; WHO Pathological and Molecular Classification; Molecular Pathogenesis; Glioma Cell Migration and Heterogeneity; Clinical Presentation, Natural History, and Prognosis; LGG Epilepsy; MRI, fMRI, DTI, Molecular Imaging; Brain Mapping Techniques in LGG; Surgical Adjuncts to Increase EOR iMRI, Flourescence, Raman Histology; Mapping Cognition and Emotion; Extent of Resection; EOR vs Molecular Classification; Chemotherapy Treatment and Trials; Radiotherapy Treatment and Trials; Higher Order Surgical Questions; and Building a Glioma Practice.

This issue of Neurosurgery Clinics, edited by Drs. Sigurd Berven and Praveen V. Mummaneni, will cover Degenerative Spinal Deformity: Creating Lordosis in the Lumbar Spine. Topics will include, but are not limited to, Spinopelvic Parameters; Location of lordosis (priority for L4-S1) and Age Adjustments; Approach Selection; Nuances of Pedicle Subtraction Osteotomy; Preventing Pseudarthrosis and PJK; The Challenge of Creating Lordosis in High Grade Dysplastic Spondylolisthesis; Sacropelvic Fixation; Evolution of the MISDEF Algorithm; Transpsoas Approach Nuances; Lateral Prepsoas Approach Nuances; Anterior Column Release; Navigation assisted MIS deformity correction; MIS TLIF; MIS PSO; and The challenge of L4-S1- fractional curves.

This issue of Neurosurgery Clinics will focus on subdural hematomas. Articles will include: Imaging of Subdural Hematomas; Chronic Subdural Natural History; Chronic Subdural Medical Management; Chronic Subdural Minimally Invasive Surgery; Chronic Subdural Craniotomy; Chronic Subdural ICU Management; and many more!

Topics include: Neoplastic Meningitis and Epidural Metastases: Evaluation and Management; Management of Brain Metastases: Surgery, Radiation, or Both?; Meningiomas/Nerve Sheath Tumors/Pituitary Tumors: Diagnosis and Treatment; Medulloblastoma/Primitive Neuroectodermal Tumor and Germ Cell Tumors: The Uncommon but Potentially Curable Primary Brain Tumors; Primary CNS Lymphoma: Overview of Current Treatment Strategies; Anaplastic Gliomas: Radiation, Chemotherapy, or Both?; Low Grade Gliomas: When and How to Treat?; Glioblastoma Multiforme: Overview of Current Treatment and Future Perspectives.

The current practice of medicine is largely moving toward applying an evidence-based approach. Evidence-based medicine is the integration of best research evidence using systematic reviews of the medical literature and then translating it into practice by selecting treatment options for specific cases based on the best research. Clinicians rely on the availability of evidence and accordingly take decisions to provide best treatment to their patients. Clinical management of neurologically compromised patients is challenging and varied; for this reason, treating physicians including neuroanesthesiologists are always in search of best available evidence for patient management and care. Essentials of Evidence-Based Practice of Neuroanesthesia and Neurocritical Care highlights the various controversies that exist in the practice of neuroanesthesia and provides conclusive evidence-based solutions. This comprehensive resource succinctly discusses evidence-based practice of neuroanesthesia based on systematic reviews in clinical neuroscience research. Topics include neurophysiology: ICP or CPP thresholds; neuropharmacology: intravenous or inhalational anesthetics; and neuromonitoring: ICP monitoring. Evidence-based practice is now an integral part of neuroscience, and this book will help residents and trainees gain knowledge to apply it to their practice. Endorsements/Reviews: "Evidence based practice is facilitating changes at a rapid pace in neuroanesthesia and neurocritical care practice. Its practice is exceedingly crucial in neuroanesthesia and neurocritical care considering the criticality of the neurologically sick patients, which leaves little or no room for error for an acceptable outcome in them. Patient management in Neuroanesthesia and neurocritical care has many contentious issues because of rapidly evolving changes in their management which require treatment guided by the latest available evidence in literature. Dr. Hemanshu Prabhakar is a strong proponent of evidence based practice for the management of neurologically ill patients both for surgical procedures and their management in neurointensive care unit. Undoubtedly, this book will be of enormous benefits to the students as well as teachers of neuroanesthesia and neurocritical care sub-specialties." -- Parmod Bithal, Editor-In-Chief, Journal of Neuroanaesthesiology and Critical Care (JNACC) - Highlights the various controversies that exist in the practice of neuroanesthesia and provides conclusive evidence-based solutions - Topics include neurophysiology: ICP or CPP thresholds; neuropharmacology: intravenous or inhalational anesthetics; and neuromonitoring: ICP monitoring - Provides residents and trainees with the knowledge to apply evidence-based practice of neuroanesthesia to their practice

Emphasising the multi-disciplinary nature of palliative care, the fourth edition of this text also looks at the individual professional roles that contribute to the best-quality palliative care.

This issue of Medical Clinics of North America, Guest Edited by Charles Argoff, MD is devoted to Chronic Pain Management. Dr. Argoff has assembled a group of expert authors to review the following topics: Chronic Pain Management: An Overview of Taxonomy, Conditions Commonly Encountered, and Assessment; The Acute to Chronic Pain Transition: Can Chronic Pain Be Prevented?; What Do We Know About the Pathophysiology of Chronic Pain? Implications for Treatment Considerations; An Overview of Pharmacologic Management of Chronic Pain; An Overview of Nonmedical Treatment of Chronic Pain; Managing Chronic Headache Disorders; Managing Osteoarthritis and Other Chronic Musculoskeletal Pain Disorders; Managing Neuropathic Pain; Managing Low Back and Other Spinal Pain Disorders; Exploring the Use of Chronic Opioid Therapy for Chronic Pain: When, How and for Whom?; The Role of Invasive Pain Management Modalities in the Treatment of Chronic Pain; Multimodal Management of Chronic Pain: What is the Evidence?; Managing Chronic Pain in Special Populations; and The Future of Pain Management as a Subspecialty: Meeting the Needs of the Patients We Care For.