Divided into fourteen chapters, this text and full-color atlas is a complete overview of the pathologic and clinical aspects of neurologic diseases. Clinical Neuropathology is written for practicing neurologists and pathologists, as well as residents and fellows preparing for the neurology and pathology boards. It provides information on the structural alterations of nervous system diseases along with their clinical manifestations. The first two chapters cover the process and goals of the neuropathologic exam and histological reactions particular to the nervous system. Subsequent chapters review major disease categories, with each section containing an overview of pathologic and clinical characteristics in general, a description of the gross and histologic features along with their clinical features, and data on pathogenetic mechanisms. Filled with tables to clarify major points, case histories to provide clinical correlates, and Board-type chapter review questions with answers and explanations, this text will be a valuable addition to all individual and reference libraries. Key Benefits: Almost 600 full color illustrations. Case histories, keyed to images, provide clinical correlation with pathology. Over 90 tables summarizing key points: useful for quick reference and exam preparation. End-of-chapter Board-type questions, with answers and explanations, for self-assessment and exam preparation.

This updated second edition provides a practical and succinct overview of basic neuropathology. Key concepts and basic principles are covered and discussed with particular focus on recent advances, classification, and genetics. Practical points are included to detail how to best use the neuropathology service and interpret the results of pathological tests. Neuropathology Simplified aims to aid the development of multidisciplinary teams and help clinical trainees understand recent advances in neuropathological disorders. The book is also relevant to trainee and resident neurologists, pathologists, and neurosurgeons.

Neuropathology, Volume 145, the latest release in the Handbook of Clinical Neurology series, includes all the major topics found in a typical neuropathology text, but differentiates itself by providing a thorough overview of the morphological background of neurological disorders for researchers and clinicians who do not specialize in pathology or its clinicopathological aspects. This volume offers strong coverage of brain imaging and advances in molecular pathology and genetics, and is particularly timely given the amount of neuropathological research currently taking place. - Provides a resource for the non-pathologist, aiding primary clinicians and researchers in the interpretation of patient symptoms and research findings - Includes standard neuropathology, but extends to clinicopathology, imaging and molecular pathology/genetics - Presents an interdisciplinary approach that can be applied in everyday clinic and research efforts

Although most textbooks of neurology contain a certain amount of pathological informa tion, neuropathology has often been treated in isolation. However, neuropathology has a close relationship to clinical neurology, neurosurgery and neuroradiology. Thus, advances in the rapidity and accuracy of pathological diagnosis have often led to changes in clinical management and, recently, improvements in clinical diagnosis, particularly CT scanning, have brought about a change in emphasis in the practice of neuropathology. In this textbook we have sought to present a widely based account of neuropathology in combination with information from clinical experience. We chose this approach in order to emphasize the close interrelation between clinician and pathologist. The book grew out of a course organised jointly by two neurologists and two neuropathologists from the Depart ments of Neuropathology and Neurology of The London Hospital and The University of Southampton. It is hoped that the book will be useful not only to pathologists, neurologists, neurosurgeons, and neuroradiologists, but also to general physicians. In a period of rapid advance in knowledge it is important to recognise how changes in the clinical and laboratory disciplines overlap. In order to make the most of consultations with pathologist colleagues the clinician must know what skills and techniques are available in the laboratory, and similarly, the pathologist must keep abreast of changes in clinical practice. In the past the clinician and pathologist have often been slow to appreciate advances in each other's fields.

Neuroimaging, Part One, a text from The Handbook of Clinical Neurology illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This first volume specifically covers a description of imaging techniques used in the adult brain, aiming to bring a comprehensive view of the field of neuroimaging to a varying audience. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, and the entire field is moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to this new horizon in the study of neurological disorders. - Provides a relevant description of the technologies used in neuroimaging, including computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and several others - Ideal resource for anyone studying the nervous system, from beginners to specialists interested in recent advances in neuroimaging of the adult brain - Discusses the application of imaging techniques to the study of brain and spinal cord disease and its use in various syndromes - Contains vibrant, colorful images to illustrate key points

This volume will concentrate on the structure and pathology of the brain, rather than the spinal cord, the peripheral nervous system or the relationships of nervous system functioning to other organs or systems of the body. The significance of other organs and systems for normal brain function is recognized and we refer to their importance throughout the text, particularly in the section on toxic and metabolic problems. Equally significant for behavior are the input mechanisms (the brain cannot be influenced unless it is reached by afferent impulses) and output mechanisms (the brain cannot respond unless it can control efferent impulses to effector organs). Despite their obvious importance, we do not attempt to provide a formal review of sensory or motor systems with relation to the brain.

Covering all aspects of neuropathology, this updated volume in the Diagnostic Pathology series is an excellent point-of-care resource for pathologists at all levels of experience and training—both as a quick reference and as an efficient review to improve knowledge and skills. The third edition is an easy-to-use, one-stop reference for the most recent clinical, pathological, histological, and molecular knowledge in the field. It offers complete information on lesions of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, vascular, and cortical dysplastic lesions, enabling you to arrive at the correct diagnosis and prepare actionable, useful reports. Incorporates new WHO Classification of Tumors of the Central Nervous System, 5th Edition Offers information on neoplasms of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, and vascular lesions, aiding you in arriving at the correct diagnosis Emphasizes surgical pathology but also provides significant content on nonneoplastic diseases that present with focal lesions, especially those that are potentially misinterpreted as neoplasms Contains a detailed molecular diagnostics chapter with a section on methylation profiling, which has become indispensable as a method of tumor classification Features new and updated chapters detailing several types of tumors that have been reclassified due to recent molecular driver information, cIMPACT-NOW recommendations, and the WHO Classification, 5th Edition

Concise yet comprehensive, Clinical Neurology, Fourth Edition builds on the success of three previous editions in helping medical students, junior doctors, and practicing physicians acquire an improved understanding of the principles of neurology.The fourth edition has been fully revised and updated to take into account current developments in the