Actions of Polish groups are ubiquitous in mathematics. In certain branches of ergodic theory and functional analysis, one finds a systematic study of the group of measure-preserving transformations and the unitary group. In logic, the analysis of countable models intertwines with results concerning the actions of the infinite symmetric group. This text develops the theory of Polish group actions entirely from scratch, ultimately presenting a coherent theory of the resulting orbit equivalence classes that may allow complete classification by invariants of an indicated form. The book concludes with a criterion for an orbit equivalence relation classifiable by countable structures considered up to isomorphism. This self-contained volume offers a complete treatment of this active area of current research and develops a difficult general theory classifying a class of mathematical objects up to some relevant notion of isomorphism or equivalence.

Actions of Polish groups are ubiquitous in mathematics. In certain branches of ergodic theory and functional analysis, one finds a systematic study of the group of measure-preserving transformations and the unitary group. In logic, the analysis of countable models intertwines with results concerning the actions of the infinite symmetric group. This text develops the theory of Polish group actions entirely from scratch, aiming to ultimately present a coherent theory of the resulting orbit equivalence classes that may allow complete classification by invariants of an indicated form. The book concludes with a criterion for an orbit equivalence relation classifiable by countable structures considered up to isomorphism.

A study of ergodic, measure preserving actions of countable discrete groups on standard probability spaces. It explores a direction that emphasizes a global point of view, concentrating on the structure of the space of measure preserving actions of a given group and its associated cocycle spaces.

This book collects the notes of the lectures given at an Advanced Course on Dynamical Systems at the Centre de Recerca Matemàtica (CRM) in Barcelona. The notes consist of four series of lectures. The first one, given by Andrew Toms, presents the basic properties of the Cuntz semigroup and its role in the classification program of simple, nuclear, separable C*-algebras. The second series of lectures, delivered by N. Christopher Phillips, serves as an introduction to group actions on C*-algebras and their crossed products, with emphasis on the simple case and when the crossed products are classifiable. The third one, given by David Kerr, treats various developments related to measure-theoretic and topological aspects of crossed products, focusing on internal and external approximation concepts, both for groups and C*-algebras. Finally, the last series of lectures, delivered by Thierry Giordano, is devoted to the theory of topological orbit equivalence, with particular attention to the classification of minimal actions by finitely generated abelian groups on the Cantor set.

Contributes to the theory of Borel equivalence relations, considered up to Borel reducibility, and measures preserving group actions considered up to orbit equivalence. This title catalogs the actions of products of the free group and obtains additional rigidity theorems and relative ergodicity results in this context.

This book, based on published studies, takes a unique perspective on the 30-year collapse of pharmaceutical industry productivity in the search for small molecule “magic bullet” interventions. The relentless escalation of inflation-adjusted cost per approved medicine in the United States — from $200 million in 1950 to $1.2 billion in 2010 — has driven industry giants to, at best, slavish imitation in drug design, and at worst, abandonment of research and embracing of widespread fraud in consumer marketing.The book adapts formalism across a number of disciplines to the strategy for design of mutilevel interventions, focusing first on molecular, cellular, and larger scale examples, and then extending the argument to the simplifications provided by the dominant role of social and cultural structures and processes in individual and population patterns of health and illness.In place of “magic bullets”, we must now apply “magic strategies” that act across both the scale and level of organization. This book provides an introductory roadmap to the new tools that will be needed for the design of such strategies./a

Presents Results from a Very Active Area of ResearchExploring an active area of mathematics that studies the complexity of equivalence relations and classification problems, Invariant Descriptive Set Theory presents an introduction to the basic concepts, methods, and results of this theory. It brings together techniques from various areas of mathem

This volume of proceedings is an offspring of the special semester Ergodic Theory, Geometric Rigidity and Number Theory which was held at the Isaac Newton Institute for Mathematical Sciences in Cambridge, UK, from Jan uary until July, 2000. Beside the activities during the semester, there were workshops held in January, March and July, the first being of introductory nature with five short courses delivered over a week. Although the quality of the workshops was excellent throughout the semester, the idea of these proceedings came about during the March workshop, which is hence more prominently represented, The format of the volume has undergone many changes, but what has remained untouched is the enthusiasm of the contributors since the onset of the project: suffice it to say that even though only two months elapsed between the time we contacted the potential authors and the deadline to submit the papers, the deadline was respected in the vast majority of the cases. The scope of the papers is not completely uniform throughout the volume, although there are some points in common. We asked the authors to write papers keeping in mind the idea that they should be accessible to students. At the same time, we wanted the papers not to be a summary of results that appeared somewhere else.

The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena. This, the 13th Transactions on Computational Systems Biology volume, guest edited by Ralph-Johan Back, Ion Petre, and Erik de Vink, focuses on Computational Models for Cell Processes and features a number of carefully selected and enhanced contributions initially presented at the CompMod workshop, which took place in Eindhoven, The Netherlands, in November 2009. From different points of view and following various approaches, the papers cover a wide range of topics in systems biology, addressing the dynamics and the computational principles of this emerging field.