The release of this second volume of CHIPS 2020 coincides with the 50th anniversary of Moore’s Law, a critical year marked by the end of the nanometer roadmap and by a significantly reduced annual rise in chip performance. At the same time, we are witnessing a data explosion in the Internet, which is consuming 40% more electrical power every year, leading to fears of a major blackout of the Internet by 2020. The messages of the first CHIPS 2020, published in 2012, concerned the realization of quantum steps for improving the energy efficiency of all chip functions. With this second volume, we review these messages and amplify upon the most promising directions: ultra-low-voltage electronics, nanoscale monolithic 3D integration, relevant-data, brain- and human-vision-inspired processing, and energy harvesting for chip autonomy. The team of authors, enlarged by more world leaders in low-power, monolithic 3D, video, and Silicon brains, presents new vistas in nanoelectronics, promising Moore-like exponential growth sustainable through to the 2030s.

The chips in present-day cell phones already contain billions of sub-100-nanometer transistors. By 2020, however, we will see systems-on-chips with trillions of 10-nanometer transistors. But this will be the end of the miniaturization, because yet smaller transistors, containing just a few control atoms, are subject to statistical fluctuations and thus no longer useful. We also need to worry about a potential energy crisis, because in less than five years from now, with current chip technology, the internet alone would consume the total global electrical power! This book presents a new, sustainable roadmap towards ultra-low-energy (femto-Joule), high-performance electronics. The focus is on the energy-efficiency of the various chip functions: sensing, processing, and communication, in a top-down spirit involving new architectures such as silicon brains, ultra-low-voltage circuits, energy harvesting, and 3D silicon technologies. Recognized world leaders from industry and from the research community share their views of this nanoelectronics future. They discuss, among other things, ubiquitous communication based on mobile companions, health and care supported by autonomous implants and by personal carebots, safe and efficient mobility assisted by co-pilots equipped with intelligent micro-electromechanical systems, and internet-based education for a billion people from kindergarden to retirement. This book should help and interest all those who will have to make decisions associated with future electronics: students, graduates, educators, and researchers, as well as managers, investors, and policy makers. Introduction: Towards Sustainable 2020 Nanoelectronics.- From Microelectronics to Nanoelectronics.- The Future of Eight Chip Technologies.- Analog–Digital Interfaces.- Interconnects and Transceivers.- Requirements and Markets for Nanoelectronics.- ITRS: The International Technology Roadmap for Semiconductors.- Nanolithography.- Power-Efficient Design Challenges.- Superprocessors and Supercomputers.- Towards Terabit Memories.- 3D Integration for Wireless Multimedia.- The Next-Generation Mobile User-Experience.- MEMS (Micro-Electro-Mechanical Systems) for Automotive and Consumer.- Vision Sensors and Cameras.- Digital Neural Networks for New Media.- Retinal Implants for Blind Patients.- Silicon Brains.- Energy Harvesting and Chip Autonomy.- The Energy Crisis.- The Extreme-Technology Industry.- Education and Research for the Age of Nanoelectronics.- 2020 World with Chips.

In this book, a global team of experts from academia, research institutes and industry presents their vision on how new nano-chip architectures will enable the performance and energy efficiency needed for AI-driven advancements in autonomous mobility, healthcare, and man-machine cooperation. Recent reviews of the status quo, as presented in CHIPS 2020 (Springer), have prompted the need for an urgent reassessment of opportunities in nanoelectronic information technology. As such, this book explores the foundations of a new era in nanoelectronics that will drive progress in intelligent chip systems for energy-efficient information technology, on-chip deep learning for data analytics, and quantum computing. Given its scope, this book provides a timely compendium that hopes to inspire and shape the future of nanoelectronics in the decades to come.

In an increasingly interconnected world, "Communication Networks Economy" provides the rational understanding necessary to provide universal access to communication means in an efficient way. This book presents the principal elements of the economics of a network as it stands today, taking into account experiences of technicians in the field. The author gives a simplified picture of the current situation in terms of structures and architecture of a network, bearing in mind the necessary quality of service and the profitability of investments, accompanied by references to recent economic works. An overview is given on the general themes of regulation and tariff principles, and the relations between supply and demand, from the perspectives of professional and residential users and network operators. Different aspects of the present situations of networks and the incidence of the Internet on the economy are also presented. In conclusion, the reader will obtain an overview of the most significant issues likely to influence the economics of communications networks as they are today.

Principles of Human Organs-on-Chips covers all aspects of microfluidic organ-on-a-chip systems, from fabrication to application and commercialization. Organ-on-a-chip models are created to mimic the structural, microenvironmental and physiological functions of human organs, providing the potential to bypass some cell and animal testing methods. This is a useful platform with widespread applications, frequently in drug screening and pathological studies. This book offers a comprehensive and authoritative reference on microfluidic organs-on-chips, spanning all key aspects from fabrication methods, cell culture systems and cell-based analysis, to dedicated chapters on specific tissue types and their associated organ-on-a-chip models, as well as their use as disease models, drug screening platforms and more. Principles of Human Organs-on-Chips helps materials scientists and biomedical engineers to better understand the specific requirements and challenges in the design and fabrication of organ-on-a-chip devices. This book also bridges the knowledge gap between medical device design and subsequent clinical applications, allowing medical professionals to easily learn about related engineering concepts and techniques. - Describes various microfluidic systems and fabrication methods - Covers models and applications for a broad range of tissue types, including liver, eye, immune, gut, and more - Offers an interdisciplinary approach, combining engineering techniques and clinical applications of organs-on-chips

This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.

Biotechnology in Healthcare presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Biotechnology has revolutionized healthcare in the last two decades by developing and introducing novel diagnostics, therapeutics, and preventive measures; whether it is noncommunicable or communicable disease, primary or secondary care, or public health, it has shown its immense potential to provide a solution to the healthcare providers, physicians, and allied health care professionals.The second volume, Applications and Initiatives, contains 19 chapters focused on the applications of biotechnology related to public healthcare, hospital management, oncology, neurodegenerative and infectious diseases, regenerative medicine, IVF, clinical trials, precision food, FMGCs, PPCPs, pharmaceuticals, and smart technologies to monitor pandemic. Further, this volume also presents government initiatives and entrepreneurship challenges in healthcare biotechnology sector.This is a valuable resource for students, biotechnologists, bioinformaticians, clinicians, and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare. - Describes various applications of novel biotechnology approaches in healthcare - Presents applications of biotechnology in primary and secondary healthcare and in public health - Discusses government initiatives, challenges and opportunities, and entrepreneurship development in the area of healthcare biotechnology

Knowledge-intensive product realization implies embedded intelligence; meaning that if both theoretical and practical knowledge and understanding of a subject is integrated into the design and production processes of products, this will significantly increase added value. This book presents papers accepted for the 9th Swedish Production Symposium (SPS2020), hosted by the School of Engineering, Jönköping University, Sweden, and held online on 7 & 8 October 2020 because of restrictions due to the Corona virus pandemic. The subtitle of the conference was Knowledge Intensive Product Realization in Co-Operation for Future Sustainable Competitiveness. The book contains the 57 papers accepted for presentation at the conference, and these are divided into nine sections which reflect the topics covered: resource efficient production; flexible production; virtual production development; humans in production systems; circular production systems and maintenance; integrated product and production development; advanced and optimized components, materials and manufacturing; digitalization for smart products and services; and responsive and efficient operations and supply chains. In addition, the book presents five special sessions from the symposium: development of changeable and reconfigurable production systems; smart production system design and development; supply chain relocation; management of manufacturing digitalization; and additive manufacturing in the production system. The book will be of interest to all those working in the field of knowledge-intensive product realization.

This book will give insight into emerging semiconductor devices from their applications in electronic circuits, which form the backbone of electronic equipment. It provides desired exposure to the ever-growing field of low-power electronic devices and their applications in nanoscale devices, memory design, and biosensing applications. Tunneling Field Effect Transistors: Design, Modeling and Applications brings researchers and engineers from various disciplines of the VLSI domain to together tackle the emerging challenges in the field of nanoelectronics and applications of advanced low-power devices. The book begins by discussing the challenges of conventional CMOS technology from the perspective of low-power applications, and it also reviews the basic science and developments of subthreshold swing technology and recent advancements in the field. The authors discuss the impact of semiconductor materials and architecture designs on TFET devices and the performance and usage of FET devices in various domains such as nanoelectronics, Memory Devices, and biosensing applications. They also cover a variety of FET devices, such as MOSFETs and TFETs, with various structures based on the tunneling transport phenomenon. The contents of the book have been designed and arranged in such a way that Electrical Engineering students, researchers in the field of nanodevices and device-circuit codesign, as well as industry professionals working in the domain of semiconductor devices, will find the material useful and easy to follow.