This book introduces the principles and concepts of chemical and biochemical sensors for analyzing medical as well as biological samples. For applications like analyzing or monitoring gastric juice or blood plasma, the potential of sensors is exceptionally large. Focussed on these applications, the interpretation of analytical results is explained. Specific advantages are compared to other analytical techniques. Numerous tables with data provide useful information not easily found elsewhere and make a handy source of reference. Ursula E. Spichiger-Keller is head of the Center for Chemical Sensors/Biosensors and Bioanalytical Chemistry at the Swiss Federal Institute of Technology (ETH) in Zurich.

This book broadly reviews the modem techniques and significant applications of chemical sensors and biosensors. Chapters are written by experts in the field – including Professor Joseph Wang, the most cited scientist in the world and renowned expert on sensor science who is also co-editor. Each chapter provides technical details beyond the level found in typical journal articles, and explores the application of chemical sensors and biosensors to a significant problem in biomedical science, also providing a prospectus for the future.This book compiles the expert knowledge of many specialists in the construction and use of chemical sensors and biosensors including nitric oxide sensors, glucose sensors, DNA sensors, hydrogen sulfide sensors, oxygen sensors, superoxide sensors, immuno sensors, lab on chip, implatable microsensors, et al. Emphasis is laid on practical problems, ranging from chemical application to biomedical monitoring and from in vitro to in vivo, from single cell to animal to human measurement. This provides the unique opportunity of exchanging and combining the expertise of otherwise apparently unrelated disciplines of chemistry, biological engineering, and electronic engineering, medical, physiological. - Provides user-oriented guidelines for the proper choice and application of new chemical sensors and biosensors - Details new methodological advancements related to and correlated with the measurement of interested species in biomedical samples - Contains many case studies to illustrate the range of application and importance of the chemical sensors and biosensors

Key features include: Self-assessment questions and exercises Chapters start with essential principles, then go on to address more advanced topics More than 1300 references to direct the reader to key literature and further reading Highly illustrated with 450 figures, including chemical structures and reactions, functioning principles, constructive details and response characteristics Chemical sensors are self-contained analytical devices that provide real-time information on chemical composition. A chemical sensor integrates two distinct functions: recognition and transduction. Such devices are widely used for a variety of applications, including clinical analysis, environment monitoring and monitoring of industrial processes. This text provides an up-to-date survey of chemical sensor science and technology, with a good balance between classical aspects and contemporary trends. Topics covered include: Structure and properties of recognition materials and reagents, including synthetic, biological and biomimetic materials, microorganisms and whole-cells Physicochemical basis of various transduction methods (electrical, thermal, electrochemical, optical, mechanical and acoustic wave-based) Auxiliary materials used e.g. synthetic and natural polymers, inorganic materials, semiconductors, carbon and metallic materials properties and applications of advanced materials (particularly nanomaterials) in the production of chemical sensors and biosensors Advanced manufacturing methods Sensors obtained by combining particular transduction and recognition methods Mathematical modeling of chemical sensor processes Suitable as a textbook for graduate and final year undergraduate students, and also for researchers in chemistry, biology, physics, physiology, pharmacology and electronic engineering, this bookis valuable to anyone interested in the field of chemical sensors and biosensors.

Electrochemical Biosensors summarizes fundamentals and trends in electrochemical biosensing. It introduces readers to the principles of transducing biological information to measurable electrical signals to identify and quantify organic and inorganic substances in samples. The complexity of devices related to biological matrices makes this challenging, but this measurement and analysis are critically valuable in biotechnology and medicine. Electrochemical biosensors combine the sensitivity of electroanalytical methods with the inherent bioselectivity of the biological component. Some of these sensor devices have reached the commercial stage and are routinely used in clinical, environmental, industrial and agricultural applications. - Describes several electrochemical methods used as detection techniques with biosensors - Discusses different modifiers, including nanomaterials, for preparing suitable pathways for immobilizing biomaterials at the sensor - Explains various types of signal monitoring, along with several recognition systems, including antibodies/antigens, DNA-based biosensors, aptamers (protein-based), and more

Sales of U.S. chemical sensors represent the largest segment of the multi-billion-dollar global sensor market, which includes instruments for chemical detection in gases and liquids, biosensors, and medical sensors. Although silicon-based devices have dominated the field, they are limited by their general inability to operate in harsh environments

Advanced Biosensors for Health Care Applications highlights the different types of prognostic and diagnostic biomarkers associated with cancer, diabetes, Alzheimer's disease, brain and retinal diseases, cardiovascular diseases, bacterial infections, as well as various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of these diseases. Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches. This book outlines the need of novel strategies for developing new systems to retrieve health information of patients in real time. It explores the potential of nano-multidisciplinary science in the design and development of smart sensing technology using micro-nanoelectrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy, that is, FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-Chip (LOC), for diagnostics and personalized health-care monitoring. It is a useful handbook for specialists in biotechnology and biochemical engineering. - Describes advanced nanomaterials for biosensor applications - Relates the properties of available nanomaterials to specific biomarkers applications - Includes diagnosis and electrochemical studies based on biosensors - Explores the potential of nano-multidisciplinary science to design and develop smart sensing technologies - Describes novel strategies for developing a new class of assay systems to retrieve the desired health information

Covering the huge developments in sensor technology and electronic sensing devices that have occurred in the last 10 years, this book uses an open learning format to encourage reader understanding of the subject. An invaluable distance learning book Applications orientated providing invaluable aid for anyone wishing to use chemical and biosensors Key features and subjects covered include the following: Sensors based on both electrochemical and photometric transducers Mass-sensitive sensors Thermal-sensitive sensors Performance factors for sensors Examples of applications Detailed case studies of five selected sensors 30 discussion questions with worked examples and 80 self-assessment questions 140 explanatory diagrams An extensive bibliography

Wearable Physical, Chemical and Biological Sensors introduces readers of all backgrounds—chemistry, electronics, photonics, biology, microfluidics, materials, and more—to the fundamental principles needed to develop wearable sensors for a host of different applications. The capability to continuously monitor organ-related biomarkers, environmental exposure, movement disorders, and other health conditions using miniaturized devices that operate in real time provides numerous benefits, such as avoiding or delaying the onset of disease, saving resources allocated to public health, and making better decisions on medical diagnostics or treatment. Worn like glasses, masks, wristwatches, fitness bands, tattoo-like devices, or patches, wearables are being boosted by the Internet of Things in combination with smart mobile devices. Besides, wearables for smart agriculture are also covered. Written by experts in their respective fields, Wearable Physical, Chemical and Biological Sensors provides insights on how to design, fabricate, and operate these sensors. - Provides a holistic view of the field, covering physical, chemical, and biosensing approaches along with the advantages of their various functionalities - Covers all necessary elements for developing wearable sensors, including materials, biorecognition elements, transductions systems, signal amplification strategies, and system design considerations - Each chapter includes examples, summaries, and references for further reading

Biosensors are making a large impact in environmental, food, biomedical, and other applications. In comparison to standard analytical detection methods, such as minimal sample preparation and handling, they offer advantages including real time detection, rapid detection of the analytes of concern, use of non-skilled personnel, and portability. The aim of this book is to focus on research related to the rapid detection of agents and weapons of bioterrorism and provide a comprehensive review of the research topics most pertinent to advancing devices applicable to the rapid real-time detection of toxicants such as microbes, pathogens, toxins, or nerve gases. The ongoing war on terrorism and the rising security concerns are driving the need for newer faster biosensors against bio-warfare agents for both military and civil defence applications. The volume brings together contributions from the most eminent international researchers in the field, covering various aspects of work not so far published in any scientific journal and often going beyond the “state of art “ . Readers of these review articles will learn new technological schemes that can lead to the construction of devices that will minimize the risk of bio-terrorism.

"Biomedical Sensors and Measurement" is an interdisciplinary book combining electronics with biology and medicine. It gives an overview of the concept and principle of biomedical sensors and measurement. First, the basic theory and technology are explained, followed by details of the physical sensors, chemical sensors, biosensors and their typical applications in biomedicine. Furthermore, the interface technology of the sensors and the typical measurement systems is presented. The large amount of vivid and specific figures and formulas will help to deepen the understanding of the fundamental and new applications involving biomedical sensors and measurement technology. The book is intended for biomedical engineers, medical physicists and other researchers and professionals in biomedicine-related specialties, especially interdisciplinary studies. Prof. Ping Wang and Dr. Qingjun Liu both work at the Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, China.