Volume 1 of the series Changing the Global Approach to Medicine introduced the concept of RNA Vector Therapy, the innovative utilization of virus-like devices to deliver RNA molecules to protein deficient cells to provide a directed medical therapy. Volume 2 greatly expands this approach to configuring enhanced virus-like transport devices to deliver various forms of therapeutic materials to specific cell types. Medial Vector Therapy includes the delivery of DNA, chemotherapy and other drug molecules, oxygen, and nutrients as well as various forms of RNA to the cells that require such therapeutic interventions. This ingenious new approach to the management of challenging diseases has the distinct advantage of administering a broad spectrum of therapeutic elements directly to the cells in need, but dramatically limits the side effects by not exposing other cells in the body to the potential harmful effects of such therapies. Also introduced in this text are the innovative concepts the Quantum Gene and the Quadsistor.

This third volume of the series Changing the Global Approach to Medicine explores the programmed command and control functions in a biologic cell. Command and control functions facilitate the intricately organized bio computer systems internal to the cell. Guidance of command and control functions is direct from static intelligence in the human genome. Recognizing all organic life shares similar biologic systems dictates that similar genetics are shared amongst species. A Prime Genome represents all of the fundamental elements and unique portions of the genomes that have ever existed on Earth. The original Prime Genome provided the general instructions necessary to create the various forms of life that have flourished. Ecometabolous is the strategy by which the Prime Genome morphed the elements of a hostile planet into a functional ecosystem with the expected outcome resulting in human form. Also introduced is the concept of the universal component of matter the tritron and sub-sub atomic particle physics, which comprise the essential fabric of the universe.

The luminous aether, a concept known for hundreds of years, is the fine essence of the universe. Over the last 130 years, mainstream science abandoned the knowledge such an aether existed. Yet, reawakening the principles of a luminous aether as the fabric of space--both within our being and surrounding us, reaching out in every direction to the very edges of the universe-- explains many unsolved mysteries. The luminous aether is a vast three-dimensional ocean of the tiniest and most elemental particles called quadsitrons. From the fusion of quadsitrons and energy, all else in the universe is constructed. The dynamics of quadsitrons interacting with energy accounts for and connects all the micro and macrophenomena that fill our lives, such as gravity, light, electrons, atoms, molecules, and magnetism. It is essential we understand and grasp the principles of this wondrous quadsitron-energy connectivity in order to advance our technology forward to interstellar travel.

The world is under constant threat of a virus evolving into a global plague. To this point, there is no direct defense against a widespread viral infection. DNA Vaccines: Design of a Gene to Eradicate HIV offers an innovative and new strategy to combat deadly viral infections. Presented is the discovery of a unique identifier for HIV. Analysis of the transcription and translation mechanisms utilized by cells leads to exploring the function of nuclear transcription factor proteins as intracellular hunter-killer molecules aimed specifically at viral genomes. Utilizing amino acid-to-nucleotide binding characteristics, taking into account Watson-Crick binding, Hoogsteen grove binding, and Vander Waals forces, modifications to existing transcription factors binding sites are undertaken. Transcription factors are altered to specifically target the unique identifier of pathogenic viruses. Binding a transcription factor directly to a viral genome is intended to silence the genome, preventing transcription if embedded in the DNA or interfering with translation if the genome is present in a cells cytoplasm as RNA. This text describes the design of an intracellular courier gene technology to make cells defensible against HIV and other lethal pathogenic viral threats.

The world is on fire, threatened by a global pandemic brought on by COVID-19. This virulent viral pathogen has rapidly infected every continent across the globe and has spread misery and death in its wake. COVID-19 is very efficient, carrying in its genetic code the instructions to construct its own personal replication machinery. This virus is very effective at copying itself, but does so with a relatively high rate of mutation to the genetic code. Given Coronavirus exhibits a frequent rate of alteration to its state, resulting in an elusive adversary, which makes treating with traditional vaccines an ongoing challenge. Fighting back with novel mRNA therapies, which can be rapidly redesigned, may offer an effective broad-spectrum therapeutic armamentarium to combat Coronavirus. Modification of the native human CD8 cell surface receptor to alert the immune system to the possible presence of the COVID-19, can result in early development of antibodies to target the pathogen. But taking the fight directly to the virus, to stop the infection in an afflicted person, is the next necessary technologic leap in pharmaceutical medicine. Redesigning native human transcription factors to create a hunter-killer protein to neutralize the COVID-19 genome is the next critical innovation necessary to eradicate viral pandemics. Cultivating a cure to counteract viral infections such as Coronavirus is now more essential than ever. Ebola, a devastatingly hostile viral infection, sits lurking, in wait. At the point Ebola evolves into an airborne viral entity, the consequences of such a noxious global pandemic will be horrific. The time is now, to secure versatile and effective vaccines and devise an effective cure to stop rampant viral infections, such as Coronavirus and Ebola.

The world is under constant threat of a virus evolving into a global plague.To this point, there is no direct defense against a widespread viral infection. Fourth Generation Biologics: Molecular Virus Killers offers an innovative, new strategy to combat deadly viral infections. Presented is the discovery of unique identifiers for the viral scourges: HIV, Herpes Simplex, the Shingles virus, the Smallpox virus and the newly emerging threats of Ebola virus and the Chikungunya virus. Analysis of the transcription and translation mechanisms utilized by cells leads to exploring the function of nuclear signaling proteins as intracellular hunter-killer molecules aimed specifically at viral genomes. Utilizing amino acid-to-nucleotide binding characteristics, taking into account Watson-Crick binding, Hoogsteen grove binding, and Vander Waals forces, modifications to existing transcription factors binding sites is undertaken. Transcription factors are altered to specifically target the unique identifier of pathogenic viruses. Binding a transcription factor directly to a viral genome is intended to silence the genome, preventing transcription if embedded in the DNA or interfering with translation if the genome is present in a cells cytoplasm as RNA. This emerging technology is then extrapolated to explore activating therapeutic nuclear genes to treat challenging medical conditions including diabetes and osteoarthritis.

The long separation of health and International Relations, as distinct academic fields and policy arenas, has now dramatically changed. Health, concerned with the body, mind and spirit, has traditionally focused on disease and infirmity, whilst International Relations has been dominated by concerns of war, peace and security. Since the 1990s, however, the two fields have increasingly overlapped. How can we explain this shift and what are the implications for the future development of both fields? Colin McInnes and Kelley Lee examine four key intersections between health and International Relations today - foreign policy and health diplomacy, health and the global political economy, global health governance and global health security. The explosion of interest in these subjects has, in large part, been due to "real world" concerns - disease outbreaks, antibiotic resistance, counterfeit drugs and other risks to human health amid the spread of globalisation. Yet the authors contend that it is also important to understand how global health has been socially constructed, shaped in theory and practice by particular interests and normative frameworks. This groundbreaking book encourages readers to step back from problem-solving to ask how global health is being problematized in the first place, why certain agendas and issue areas are prioritised, and what determines the potential solutions put forth to address them? The palpable struggle to better understand the health risks facing a globalized world, and to strengthen collective action to deal with them effectively, begins - they argue - with a more reflexive and critical approach to this rapidly emerging subject.

The field of lifestyle medicine, which is the study of how daily habits and actions impact on both short- and long-term health and quality of life, continues to expand globally. The scientific and medical literature that supports the success of these lifestyle habits and actions is now overwhelming. Thousands of studies provide evidence that regular physical activity, maintenance of a health body weight, following sound nutritional practices, stress reduction, and other good practices all profoundly impact both health and quality of life. Following its predecessors, Lifestyle Medicine, Third Edition, is edited by lifestyle medicine pioneer, cardiologist Dr. James Rippe. This edition has been thoroughly updated and represents the expert opinions of 20 section editors as well as more than 150 expert chapter authors whose knowledge span all aspects of this emerging discipline. Topics cover lifestyle medicine practices including regular physical activity, proper nutrition, and weight management. These principles are applied to the prevention and or treatment of a wide variety of chronic conditions ranging from heart disease and diabetes to cancer, mental health, addiction, and injury prevention. This book serves as evidence base for individuals who wish to practice lifestyle medicine or incorporate some of its principles into either general medicine or subspecialty practice. It provides valuable information to healthcare workers in the fields of nutrition, exercise physiology, psychology, behavioral medicine, health promotion, and public policy where lifestyle medicine principles play an ever-increasing role.

Since the publication of the first volume of Contemporary Developments and Perspectives in International Health Security, a lot has happened in this rapidly evolving area. Perhaps the most dominant global event of the past eighteen months is the COVID-19 pandemic. Within this general context, the importance of the multiple and diverse international health security (IHS) subdomains is becoming evident, especially when one begins to appreciate the interconnectedness of the modern world and the interdependence of various existing societal systems. Moreover, this complexity presents our civilization with both dangers and opportunities, and among the most pronounced opportunities is our ability to effectively “work together and coordinate” as humanity. With a goal to summarize and synthesize our collective experiences from the COVID-19 pandemic, this second tome of Contemporary Developments and Perspectives in International Health Security is a repository of knowledge and a practical resource for those who seek to learn about the current pandemic as well as for those who may already be preparing for the “next pandemic” or as yet unforeseen IHS threats. In addition to the COVID-19 global response, topics discussed in this book include climate change, mental health, supply chain management, and clinical diagnostics, among others.

Recognized as an outstanding educational product by the 2001 NASA Earth Science Enterprise Education Product Peer Review "The purpose of this textbook on global ecosystem change and human health is twofold:(1) to raise awareness of changes in human health related to global ecosystem change and (2) to expand the scope of the traditional curriculum in environmental health to include the interactions of major environmental forces and public health on a global scale."—from the Introduction Ecosystem Change and Public Health focuses on how human health is affected by global ecosystem changes. It is the first textbook devoted to this emerging field, offering a global perspective on research methods and emphasizing empirical investigations of health outcomes in combination with integrated assessment for policy development. The book covers such topics as global climate change, stratospheric ozone depletion, water resources management, and ecology and infectious disease. Case studies of cholera, malaria, the effects of water resources, and global climate change and air pollution illustrate the analysis and methodology. The book also includes a resource center describing places to start searches on the World Wide Web, guidelines for finding and evaluating information, suggested study projects, and strategies for encouraging communication among course participants.