This issue of Physical Medicine and Rehabilitation Clinics of North America is devoted to "Difficult to Treat Pain Syndromes," and is edited by Adam L. Schreiber, DO of the Jefferson Medical College of Thomas Jefferson University. Articles in this issue will include: Carpal Tunnel Syndrome Diagnosis; Non-surgical Treatment of Carpal Tunnel Syndrome; Parsonage Turner Syndrome Diagnosis and Treatment; Trochanteric Pain Syndrome Diagnosis and Treatment; Complex Regional Pain Syndrome Diagnosis and Treatment; Discogenic Spine Pain Syndrome Diagnosis and Treatment; Failed Back Surgery Syndrome Diagnosis and Treatment; Myofascial Pain Syndrome Diagnosis and Treatments; Opioid Syndrome Diagnosis and Treatment; Spinal Cord Pain Syndrome Diagnosis and Treatment; Cerebral Vascular Accident Hemishoulder Pain Syndrome Diagnosis and Treatment; and Cancer Pain Syndromes.

This issue of Physical Medicine and Rehabilitation Clinics of North America is devoted to "Amputee Rehabilitation." Editor Robert Meier, III, MD is the Medical Director of the Amputee Services of America and has assembled the top experts to review this important topic. Articles in this issue include: Principles of Contemporary Amputee Rehabilitation; Etiology and Demographics of Amputation; Surgical Techniques for Ideal Outcomes; Pre-prosthetic Care; Prosthetic Choices for Leg and Arm Amputees; Devising the Prosthetic Prescription and Typical Examples; Prosthetic Training; Complications Following an Amputation; Outcomes Measurement; Gait Evaluation for the Leg Amputee; Innovative Techniques and Future Options; Emotional Adaptation to Limb Loss; Pain Management for the Amputee; and Amputation Classification and Functional Outcomes.

Children with disabilities represent a unique population within pediatrics. Pediatric rehabilitation focuses on maximizing the function and enhancing the lives of children with a wide range of conditions such as cerebral palsy, spina bifida, stroke, brain injury, genetic abnormalities and other developmental disabilities.

Physiatrists design plans that not only treat chronic pain, but also the whole patient who lives with the pain. Causes of chronic pain can include arthritis, work injuries, failed back surgery, foot and ankle injuries, knee and hip injuries, neck, shoulder, and back injuries, nerve (neuropathic) pain, etc. This issue will focus on everything from assessment, to various treatment options (medications and injections), as well as rehab.

This issue includes a range of topics in SCI from acute neuroprotection to chronic complications, focusing on some of the technological advances that have informed specific areas.

This issue is a comprehensive, multi-disciplinary state-of-the-art review focusing on the athlete as a whole. The articles explore the impact of excessive activity, new therapies and performance enhancement interventions on the musculoskeletal, neurological and psychological aspects of the athlete.

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

This issue of Physical Medicine and Rehabilitation Clinics, guest edited by Drs. Eapen Blessen and David Cifu, will discuss a number of important topics related to Polio. This issue of one of four issues selected each year by series Consulting Editor, Santos Martinez. Topics covered in the issue will cover the following, in relation to Telerehabiliation: spinal cord injury, amputee rehabiliation, stroke, traumatic brain injury, pain management, MS/ALS, pediatric care, geriatric care, wound management, persons with disabilities, postoperative orthopedic care, telewellness, logistics of telerehab and innovative approaches to delivering therapy.

This issue of Physical Medicine and Rehabilitation Clinics, guest edited by Drs. John L. Lin, will discuss a number of important topics around Spinal Cord Injury. This issue of one of four issues selected each year by series Consulting Editor, Santos Martinez. Topics discussed in this issue include, but are not limited to: Updates for the International Standards for Neurological Classification of Spinal Cord Injury, Approaching Prognosis for Recovery after SCI, Cognitive Dysfunction in Persons with Spinal Cord Injuries, Spinal Cord Injury Pain: updated for the 21st century, Pulmonary management in patients with spinal cord injury, Therapeutic interventions to improve mobility with spinal cord injury related upper motor neuron syndromes, Neurogenic bowel management using trans-anal irrigation by persons with spinal cord injury, Heterotopic Ossification: beyond etidronate, Orthopedic Surgical Management of Upper Extremity Dysfunctions in Pediatric Populations with Spinal Cord injury, and Vocational Rehab and employment after spinal cord injury, among others.

In this issue of Physical Medicine and Rehabilitation Clinics Guest Editor Santos Martinez brings his considerable expertise to the topic of Non-Spine Ablation Procedures. Top experts in the field cover key topics such as Thoraco-abdominal Ablation, Sacroiliac Ablation Techniques, Ankle-Foot Ablation Procedures, and more. - Provides in-depth, clinical reviews on Non-Spine Ablation Procedures, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 16 relevant, practice-oriented topics including Science of Radiofrequency Ablation; Cranio-Facial Conditions and Ablation; Less Common Pelvic Ablation Procedures; and more.