Cell Instructive Materials to Control and Guide Cell Function: Programmable Bioactive Interfaces looks at the key determinants of the dynamic interface between cell and materials and how this can be applied in developing new, bioactive biomaterials surfaces. The interface between cell and synthetic materials has attracted considerable scientific and technological interest, leading to the awareness that functional interfaces can actively guide and control specific adhesion and recognitions events. - Introduces readers to the fundamentals of complex cell-material interface dynamics - Provides valuable tools for the control of the interfacial dynamics to instruct and control cells or tissues functions - Covers the prospect of encoding specific cell instructions on, or within, a biomaterial by micro- and nano-patterning materials features

Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. - Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration - Explains the importance and future potential of regenerative medicine to the transplant community - Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions

The present book discusses topics related to research and development of materials and devices at nanoscale size and their respective application in medicine and biomedicine. The individual chapters give a detailed state of the art overview to the distinct topic. Apparently disconnected fields - life sciences, biomedicine, chemistry, physics, medicine and engineering - will be bridged with a highly interdisciplinary view onto each subject.

Composite Materials presents recent developments and state-of-the-art achievements in the science and technology of composites. It identifies and discusses key and emerging issues for future progress in the multidisciplinary field of composites. By bringing together leading experts and promising innovators from research institutions and academia, Composite Materials highlights unresolved issues and identifies opportunities for long-term research needs to provide the reader with a vision for the future in various fields of application of composite materials. A few of the many future directions highlighted in the book are increasingly multifunctional properties; complex, hybrid and nanoreinforced materials; and tailoring in multiple dimensions and directions. The wider areas covered include, but are not limited to, the following: biomedical engineering, civil engineering, aerospace engineering, automotive engineering, and naval engineering. Composite Materials is designed to increase the reader’s understanding of the state of the art of composite materials in a variety of industrial sectors and to explore future needs and opportunities. It will therefore be of use to professionals working in the composites industry, research centers, and academia, who already have a graduate-level knowledge of composite materials.

This book is a printed edition of the Special Issue " Hydrogels in Tissue Engineering" that was published in Gels

Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics. - Presents a self-contained work for the field of musculoskeletal tissue engineering and regenerative medicine - Focuses on how materials of structures can be designed to be resistant while promoting viable grafts - Contains major tissue types that are covered with a strategy for each material and structure

This book focuses on advances made in both materials science and scaffold development techniques, paying close attention to the latest and state-of-the-art research. Chapters delve into a sweeping variety of specific materials categories, from composite materials to bioactive ceramics, exploring how these materials are specifically designed for regenerative engineering applications. Also included are unique chapters on biologically-derived scaffolding, along with 3D printing technology for regenerative engineering. Features: Covers the latest developments in advanced materials for regenerative engineering and medicine. Each chapter is written by world class researchers in various aspects of this medical technology. Provides unique coverage of biologically derived scaffolding. Includes separate chapter on how 3D printing technology is related to regenerative engineering. Includes extensive references at the end of each chapter to enhance further study.

This book covers the latest bio-inspired materials synthesis techniques and biomedical applications that are advancing the field of tissue engineering. Bio-inspired concepts for biomedical engineering are at the forefront of tissue engineering and regenerative medicine. Scientists, engineers and physicians are working together to replicate the sophisticated hierarchical organization and adaptability found in nature and selected by evolution to recapitulate the cellular microenvironment. This book demonstrates the dramatic clinical breakthroughs that have been made in engineering all four of the major tissue types and modulating the immune system. Part I (Engineering Bio-inspired Material Microenvironments) covers Bio-inspired Presentation of Chemical Cues, Bio-inspired Presentation of Physical Cues, and Bio-inspired Integration of Natural Materials. Part II (Bio-inspired Tissue Engineering) addresses tissue engineering in epithelial tissue, muscle tissue, connective tissue, and the immune system.