This Research Topic aims to collect all the Case Reports submitted to the General Cardiovascular Medicine section. All the Case Reports submitted to this collection will be personally assessed by the Specialty Chief Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it. Case Reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only Case Reports that are original and significantly advance the field will be considered: 1) RARE case with TYPICAL features 2) FREQUENT case with ATYPICAL features 3) Cases with a convincing response to new treatments, i.e. single case of off-label use

This Research Topic aims to collect all case reports submitted to structural interventional cardiology section. All the case reports submitted to this collection will be assessed by a senior Associate Editor before beginning the peer review process. Please make sure your article adheres to the following guidelines before submitting. Case reports highlight unique cases of patients that present with an unexpected diagnosis, treatment outcome, or clinical course. Only case reports that are original and significantly advance the field will be considered: 1) RARE case with TYPICAL features 2) FREQUENT case with TYPICAL features 3) Cases with a convincing response to new treatments Case report format: • Maximum word count: 3000 words • Title: Case Report: "area of focus" • Abstract • Introduction: including what is unique about the case and medical literature references. • Case description: including de-identified patient information, relevant physical examination and other clinical findings, relevant past interventions, and their outcomes • A figure or table showcasing a timeline with relevant data from the episode of care • Diagnostic assessment, details on the therapeutic intervention, follow-up, and outcomes as specified in the CARE guidelines • Discussion: strengths and limitations of the approach to the case, discussion of the relevant medical literature (similar and contrasting cases), take-away lessons from the case • Patient perspectives

The aim of this book, part of the European Society of Intensive Care Medicine (ESICM) textbook series and designed by the NEXT Committee of the European Society of Intensive Care Medicine, is to provide the readers with a unique review of the main syndromes in Intensive Care Medicine by means of a collection of clinical cases. The book is structured in six sections (severe infections and sepsis, respiratory medicine, cardiovascular medicine, neurocritical care and severe trauma, severe endocrine and metabolic disorders, and severe inflammatory disorders), that allow the reader to focus on a specific area. Each section begins with an “introductory chapter” to maintain cohesion. Within each section, every chapter corresponds to a clinical case covering different aspects of a relevant disease. All the chapters have a uniform design: introduction/background, case presentation, investigations, differential diagnosis, treatment, evolution, outcome and follow-up, and discussion. The target audience of this work includes university students, fellows of intensive care medicine, critical care and emergency medicine residents, and experienced physicians aiming to review the most relevant syndromes of the specialty.