This issue of Interventional Cardiology Clinics is devoted to Carotid and Cerebrovascular Disease. Expert authors review the most current information available about diagnosing cerebral artery disease and managing carotid and cerebral artery stenosis. Keep up-to-the-minute with the latest developments in cerebrovascular disease interventions.

This issue of Interventional Cardiology Clinics is devoted to Carotid and Cerebrovascular Disease. Expert authors review the most current information available about diagnosing cerebral artery disease and managing carotid and cerebral artery stenosis. Keep up-to-the-minute with the latest developments in cerebrovascular disease interventions.

Cerebrovascular disease results in huge health expenditures, multiple recurring physician visits, and a great number of surgical and non-surgical treatments along with research into causes and prevention. This issue addresses therapies, early therapies, diagnoses, and prevention. Topics include: Endovascular Treatment of Acute Ischemic Stroke; Acute Treatment of Blood Pressure after Ischemic Stroke and Intracerebral Hemorrhage; Diagnostic Evaluation for Non-traumatic Intracerebral Hemorrhage; Prevention of Recurrent Stroke in Patients with Patent Foramen Ovale; Management of Asymptomatic Carotid Stenosis; Stenting or Endarterectomy for Patients with Symptomatic Carotid Stenosis; The Therapeutic Value of Laboratory Testing for Hypercoagulable States in Secondary Stroke Prevention; Diagnosis and Treatment of Carotid and Vertebral Artery Dissection; Recurrent Stroke while on Anti-platelet Therapy; Anti-platelet and Anti-coagulant Therapy after Intracerebral Hemorrhage; Diagnosis and Treatment of Isolated Central Nervous System Angiitis/Vasculitis; Statins for Aneurysmal Subarachnoid Hemorrhage; Expansion of IV-tPA eligibility beyond NINDS and ECASS III criteria; and Treatment of Unruptured Arteriovenous Malformations. William J Powers MD, renowned for his clinical work with Stroke and Research in Cerebral blood flow and metabolism, and stroke treatment and prevention, leads this issue of Neurologic Clinics, with authors renown in the field.

Among the most recently developed procedures for treating heart disease in a minimally invasive way are the techniques for percutaneous treatment of valvular heart disease. These are important advances because the only alternative is open heart surgery, which is not an option for many high-risk patients. This issue provides a detailed description of several percutaneous procedures, including trans-catheter aortic valve implantation.

This issue of Interventional Cardiology Clinics reviews pharmacologic agents currently used to treat patients in the cath lab. All the pharmaceutical knowledge an interventionalist needs is summarized in this handy reference.

In this issue of Interventional Cardiology Clinics, guest editor Dr. Matthew James Daniels brings his considerable expertise to the topic of Left Atrial Appendage Occlusion. Top experts in the field cover key topics such as follow-up imaging after appendage occlusion, completed appendage closure trials and registries, future LAAC trials, and more. - Contains 12 relevant, practice-oriented topics including left atrial thrombus—are all atria and appendages equal?; left atrial appendage occlusion—a choice or a last resort, and how to approach the patient; is pre-cathlab planning for left atrial appendage occlusion optional or essential?; intra-procedureal imaging for appendage occlusion—the case for intracardiac echo; and more. - Provides in-depth clinical reviews on left atrial appendage occlusion, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

The entire spectrum of vascular disease is examined in this issue of Cardiology Clinics. Topics include carotid artery disease, endovascular interventions for thoracic and abdominal aortic aneurismal disease, critical limb ischemia, contemporary treatment of venous thromboembolic disease, renal artery stenosis, resistant hypertension, advances in peripheral arterial disease revascularization, stroke interventions, medical management of PAD, pre-operatory evaluation of vascular patients.

Peripheral vascular disease (PVD) is a slow and progressive circulation disorder. It may involve disease in any of the blood vessels outside of the heart and diseases of the lymph vessels—arteries, veins, or lymphatic vessels. This issue of Interventional Cardiology Clinics examines the epidemiology, diagnosis, and treatment of this pandemic disease.

This issue of Interventional Cardiology Clinics, guest edited by Dr. Herbert Aronow, will discuss Updates in Peripheral Vascular Intervention. This issue is one of four selected each year by the series Editor-in-Chief, Dr. Matthew Price. Topics discussed in this issue will include: Vascular access, alternative vascular access and vascular closure/hemostasis, Wires, catheters and sheaths, balloons and stents, Plaque modification (eg., atherectomy, lithoplasty) devices, Embolic protection, Renal and mesenteric artery intervention, Iliac intervention, Fem-pop intervention, Below-the-knee intervention, Acute limb ischemia intervention, Catheter-directed therapy for pulmonary embolism, Intervention for liofemoral DVT and May Thurner, Venous ablation, among others.

Over 5.7 million people in America carry a diagnosis of heart failure, the incidence of which approaches 1 in 100 people over the age of 65. The cost to society is estimated at $29 billion annually and over 1.1 million hospital admissions. For hospitalized heart failure patients, the 30-day readmission rate approaches 25%. As our population ages these numbers are expected to grow. This issue of Cardiology Clinics helps practitioners to manage patients at all ACC/AHA stages of heart failure and addresses key issues that include sudden cardiac death, arrhythmias, acute decompensated heart failure, and heart failure with preserved ejection fraction.