Calcium Signalling And Disease
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Author |
: Mounia Chami |
Publisher |
: MDPI |
Total Pages |
: 162 |
Release |
: 2021-04-22 |
ISBN-10 |
: 9783036504988 |
ISBN-13 |
: 3036504982 |
Rating |
: 4/5 (88 Downloads) |
Synopsis Calcium Signalling in Alzheimer’s Disease by : Mounia Chami
Alzheimer’s disease (AD) is the most well-known neurodegenerative disorder, causing dementia. In recent decades, several studies have reported calcium dysregulation in AD occurring through the intervention of several calcium receptors and channels, and affecting different cellular compartments, such as mitochondria, the endoplasmic reticulum, lysosomes, and microdomains within the plasma membrane. Calcium signalling dysregulation is now considered a common proximal cause of dysfunctional neurons and glial supporting cells. This book gathers the newest results and advances in calcium signaling deregulation mechanisms in AD, how they are linked to other players involved in AD, and the potential therapies targeting calcium alterations to treat AD.
Author |
: Ernesto Carafoli |
Publisher |
: Springer Science & Business Media |
Total Pages |
: 591 |
Release |
: 2007-09-29 |
ISBN-10 |
: 9781402061912 |
ISBN-13 |
: 1402061919 |
Rating |
: 4/5 (12 Downloads) |
Synopsis Calcium Signalling and Disease by : Ernesto Carafoli
Authors highlight several promising discoveries in the field of calcium signaling that provide new information about both genetic and acquired pathologies. Their discussions will give you new insights into the underlying causes of congenital and acquired diseases and point the way to new, even more promising research and therapies.
Author |
: Senthilkumar Rajagopal |
Publisher |
: Springer |
Total Pages |
: 106 |
Release |
: 2017-09-28 |
ISBN-10 |
: 9789811051609 |
ISBN-13 |
: 9811051607 |
Rating |
: 4/5 (09 Downloads) |
Synopsis Calcium Signaling: From Physiology to Diseases by : Senthilkumar Rajagopal
This book focuses on disorders of calcium channels and the use of drugs to treat calcium-related disorders and their associated toxicities. In particular, it discusses the role of various natural products and their attributes in preventing problems associated with calcium imbalances. In addition, the book analyzes trends in the processing of natural products using nanotechnology and their implications in calcium-related disorders. Lastly, it explores some of the most promising aspects of research into calcium signalling disorders – which is especially important, given the wide variety of cellular processes that are controlled by calcium ions – and provides a trustworthy source of up-to-date information in this area of research.
Author |
: Francesco Moccia |
Publisher |
: MDPI |
Total Pages |
: 463 |
Release |
: 2019-01-21 |
ISBN-10 |
: 9783038975373 |
ISBN-13 |
: 3038975370 |
Rating |
: 4/5 (73 Downloads) |
Synopsis Calcium Signaling in Human Health and Diseases by : Francesco Moccia
This book is a printed edition of the Special Issue "Calcium Signaling in Human Health and Diseases" that was published in IJMS
Author |
: G. V. Sherbet |
Publisher |
: CRC Press |
Total Pages |
: 385 |
Release |
: 2000-11-29 |
ISBN-10 |
: 9781420041293 |
ISBN-13 |
: 1420041290 |
Rating |
: 4/5 (93 Downloads) |
Synopsis Calcium Signalling in Cancer by : G. V. Sherbet
Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an important feat
Author |
: Md. Shahidul Islam |
Publisher |
: Springer Nature |
Total Pages |
: 1110 |
Release |
: 2019-10-23 |
ISBN-10 |
: 9783030124571 |
ISBN-13 |
: 3030124576 |
Rating |
: 4/5 (71 Downloads) |
Synopsis Calcium Signaling by : Md. Shahidul Islam
This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author |
: Francesco Moccia |
Publisher |
: |
Total Pages |
: 1 |
Release |
: 2019 |
ISBN-10 |
: 3038975389 |
ISBN-13 |
: 9783038975380 |
Rating |
: 4/5 (89 Downloads) |
Synopsis Calcium Signaling in Human Health and Diseases by : Francesco Moccia
Intracellular Ca2+ signaling is witnessing an amazing resurgence of interest. In addition to traditional Ca2+ aficionados, an astonishing (and growing) number of colleagues from all around the world have started to devote a large part of their research to gain insights into the role of Ca2+ signaling in health and disease. This is why calcium ions interact with virtually every signal transduction pathway not only in mammalian cells, but also across the phylogenetic tree, thereby, driving or modulating most, if not all, cellular functions, ranging from fertilization to apoptosis, passing through learning and memory, cardiac contractility, and immune response. This book gathers a collection of original research articles and reviews by a number of renowned experts who aim to present the state of the art of many pathophysiological aspects of intracellular Ca2+ signaling, such as embryonic development, immune response, extracellular Ca2+ signaling, neoplastic transformation, muscle hypertrophy, pulmonary inflammation, and P2X receptor gating.
Author |
: Juliusz Ashot Kozak |
Publisher |
: CRC Press |
Total Pages |
: 343 |
Release |
: 2017-07-14 |
ISBN-10 |
: 9781498752732 |
ISBN-13 |
: 149875273X |
Rating |
: 4/5 (32 Downloads) |
Synopsis Calcium Entry Channels in Non-Excitable Cells by : Juliusz Ashot Kozak
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
Author |
: Mylo Sanders |
Publisher |
: American Medical Publishers |
Total Pages |
: 0 |
Release |
: 2023-09-26 |
ISBN-10 |
: 1639276114 |
ISBN-13 |
: 9781639276110 |
Rating |
: 4/5 (14 Downloads) |
Synopsis Calcium Signaling in Biology and Medicine by : Mylo Sanders
The process that increases low cytoplasmic concentrations in order to activate specific, essential events required by the cell is defined as calcium signaling. It uses calcium ions (Ca2+) to communicate and carry out intracellular processes often as a step in signal transduction. Calcium signaling plays a crucial role in the regulation of a diverse set of essential functions within the human body. The management of various neurodegenerative disorders such as Alzheimer's disease (AD), Huntington's disease (HD), and Parkinson's disease (PD) requires calcium signaling. It has been observed that disruption in calcium signaling may lead to synaptic deficits which further leads to accumulation of Aβ plaques and neurofibrillary tangles. Calcium plays an important role in various biological processes and calcium signaling has been linked to various diseases. Therefore, it is currently being explored as a therapeutic target for various types of cancer. This book elucidates the concepts and innovative models around prospective developments with respect to the importance of calcium signaling in biology and medicine. It will serve as a valuable source of reference for those interested in this field of study.
Author |
: Jonathan Soboloff |
Publisher |
: CRC Press |
Total Pages |
: 258 |
Release |
: 2017-03-27 |
ISBN-10 |
: 9781498705097 |
ISBN-13 |
: 149870509X |
Rating |
: 4/5 (97 Downloads) |
Synopsis Signaling Mechanisms Regulating T Cell Diversity and Function by : Jonathan Soboloff
T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.