Featuring the contributions of leading faculty, this new edition provides a succinct overview of the most important aspects of pharmacology necessary for a basic understanding of the subject. It reviews the concepts, clinical applications and side effects of pharmacology, placing an emphasis on practical applications of the material, whenever possible. More than 480 full-color illustrations explain important processes, while color-coded boxes for major drugs, therapeutic overviews, clinical problems, and trade names—as well as USMLE-style self-assessment questions with answers and rationales—reinforce your mastery of the information. A consistent style of writing—and more focused, concise content—provide for better learning of the essentials. Online access to Student Consult—where you’ll find 15 pharmacology animations...150 USMLE-style questions...and more—further enhances your study and prepares you for exams. Includes online access to Student Consult where you’ll find USMLE-style questions, animations showing the actions of various important toxins, and much more. Focuses on the essential aspects of pharmacology for a solid foundation of knowledge in the subject. Includes more than 480 full-color illustrations that explain key pharmacologic processes. Provides between 4 and 6 USMLE-style self-assessment questions at the end of each chapter—with answers and full explanations in the appendix—that help you prepare for exams and master the material. Uses a templated format that promotes more effective and efficient learning. Presents color-coded boxes in each chapter that emphasize key points. Features a clinical emphasis throughout on both the basic science of pharmacology and its clinical relevance. Includes new Gold Standard content on Student Consult with 200 Professional Drug Monographs for additional information on generic and brand names, mechanism of action, pharmacokinetics, indications and dosage, drug interactions, patient education and much more! Features a more consistent style of writing—as well as focused, concise content—for enhanced learning of the essentials. Presents chapters in a re-arranged order for a more logical approach to learning. Includes additional biochemistry and physiology information in the introduction for each section for greater understanding.

Brody's Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives. What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals. - Contains all the essential aspects of pharmacology – suitable for exam preparation - Full color illustrations explain important processes and color-coded boxes enhance understanding - Therapeutic overviews, clinical problems and trade names – everything you need to know - Self-assessment questions and further reading to reinforce learning - Current developments for each class of drugs and how information relates to students in the healthcare professions bring learning to life - Updated content throughout - Pharmacodynamics chapter revised to include discussions of positive and negative allosteric modulators, as well as biased agonism - Pharmacogenetics chapter considers genetic variations and their relationship to drug responses - Section on cancer drugs revised to reflect major advances - New chapter on immunological and cell-based therapies

Focusing on the essential aspects of pharmacology you need to know, Brody‘s Human Pharmacology, 6th Edition, keeps you fully up to date with all that’s new in the field. Streamlined content, a new organizational approach, and thoroughly updated information ensure your grasp of key concepts and prepare you for exams. Nearly 500 full-color illustrations explain important processes, while color-coded boxes for major drugs, therapeutic overviews, clinical problems, and trade names reinforce your mastery of the information. The 6th Edition of this easy-to-use text is now fully up to date with: NEW chapter devoted entirely to pharmacogenomics and personalized medicine. NEW chapter on cannabinoids and their use for pain and other disorders, in light of recent legalization in many states. NEW chapters on recent developments in the treatment of Alzheimer's disease, ADHD and the latest treatments for HIV. NEW section on pain management. NEW section in each chapter covering "Clinical Relevance for Healthcare Professionals" that provides important information specific to physical therapists, dentists and dental hygienists, and many other medical professionals. Plus these student-friendly features: A new organizational approach, focusing on integration and systems-based learning. Contributions from leading faculty who cover the most important aspects of pharmacology necessary for a basic understanding of the subject, including concepts, clinical applications, and side effects. USMLE-style self-assessment questions at the end of every chapter, answers and rationales in the Appendix. Evolve Instructor Resources, including a downloadable image and test bank, are available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com

Thoroughly updated from the previous edition, this book provides an overview of the most important aspects of pharmacology--focusing on the concepts, clinical applications, and side effects that are considered essential knowledge in the field. Covers gene therapy, eating disorders and obesity, herbal and natural products, the treatment of neurological disorders, including Alzheimer's disease, and other rapid expanding areas.

Clinical Trials, Second Edition, offers those engaged in clinical trial design a valuable and practical guide. This book takes an integrated approach to incorporate biomedical science, laboratory data of human study, endpoint specification, legal and regulatory aspects and much more with the fundamentals of clinical trial design. It provides an overview of the design options along with the specific details of trial design and offers guidance on how to make appropriate choices. Full of numerous examples and now containing actual decisions from FDA reviewers to better inform trial design, the 2nd edition of Clinical Trials is a must-have resource for early and mid-career researchers and clinicians who design and conduct clinical trials. - Contains new and fully revised material on key topics such as biostatistics, biomarkers, orphan drugs, biosimilars, drug regulations in Europe, drug safety, regulatory approval and more - Extensively covers the "study schema" and related features of study design - Incorporates laboratory data from studies on human patients to provide a concrete tool for understanding the concepts in the design and conduct of clinical trials - Includes decisions made by FDA reviewers when granting approval of a drug as real world learning examples for readers

Unique among pharmacology textbooks, HUMAN PHARMACOLOGY: MOLECULAR TO CLINICAL organizes drugs of a class according to the characteristics of the class, with individual drugs discussed in relation to other drugs of the class. This approach helps students understand strengths and weaknesses of drugs, both in comparison with each other and in certain clinical conditions. The standard format allows for quick reference, and the more than 400 full-color illustrations focus on processes and mechanisms. Material is current, with changes reflecting today's pharmacotherapy. Unique New Horizons section discusses drugs being evaluated by the FDA for use in the next two to three years. Hundreds of color-coded boxes and tables allow for rapid access, and summary tables are now more "crammable." Superb index gives user quick access to specific information. Hundreds of excellent color illustrations describe important processes, structures, and interactions. USMLE-type questions at the ends of chapters allow for on-going self-assessment.

This core text offers LPN/LVN students a clear, concise introduction to pharmacology, focusing on basic principles and the nurse's responsibility in drug administration. Organized by body system, the book examines pharmacologic properties and therapeutic applications of drug classes. Summary Drug Tables present generic and trade drug names, uses, adverse reactions, and usual dosage ranges. This edition has thoroughly updated drug information, a new "Pharmacology in Practice" case study feature, Nursing Alerts, Lifespan Alerts, Chronic Care Alerts, Diversity Alerts, and additional material on the nursing process. Including a FREE copy of Lippincott’s Photo Atlas of Medication Administration, a bound CD-ROM, a companion website includes an NCLEX® alternate item format tutorial, a Spanish-English audio glossary, monographs on 100 most commonly prescribed drugs, Listen and Learn, Concepts in Action animations, Watch and Learn video clips, and Dosage Calculation Quizzes. The full text is also available online. Online Tutoring powered by Smarthinking—Free online tutoring, powered by Smarthinking, gives students access to expert nursing and allied health science educators whose mission, like yours, is to achieve success. Students can access live tutoring support, critiques of written work, and other valuable tools.

FDA's Drug Review Process and the Package Label provides guidance to pharmaceutical companies for writing FDA-submissions, such as the NDA, BLA, Clinical Study Reports, and Investigator's Brochures. The book provides guidance to medical writers for drafting FDA-submissions in a way more likely to persuade FDA reviewers to grant approval of the drug. In detail, the book reproduces data on efficacy and safety from one hundred different FDA-submissions (NDAs, BLAs). The book reproduces comments and complaints from FDA reviewers regarding data that are fragmentary, ambiguous, or that detract from the drug's approvability, and the book reveals how sponsors overcame FDA's concerns and how sponsors succeeded in persuading FDA to grant approval of the drug. The book uses the most reliable and comprehensive source of information available for writing FDA-submissions, namely text and data from NDAs and BLAs, as published on FDA's website. The source material for writing this book included about 80,000 pages from FDA's Medical Reviews, FDA's Clinical Pharmacology Reviews, and FDA's Pharmacology Reviews, from one hundred different NDAs or BLAs for one hundred different drugs. Each chapter focuses on a different section of the package label, e.g., the Dosage and Administration section or the Drug Interactions section, and demonstrates how the sponsor's data supported that section of the package label. - Reveals strategies for winning FDA approval and for drafting the package label - Examples are from one hundred FDA-submissions (NDAs, BLAs) for one hundred different drugs, e.g., for oncology, metabolic diseases, autoimmune diseases, and neurological diseases - This book uses the most reliable and comprehensive source of information available for writing FDA-submissions, namely, the data from NDAs and BLAs as published on FDA's website at the time FDA grants approval to the drug

This "real-world" approach allows students to come away with a realistically informed view of the basis for much of our understanding of nutritional biochemistry.