"So here I lay here in the cold, mentally shattered, physically broken, bleeding out and waiting for the sweet silence and darkness of death to come finally take its hold on me. A lot of things start to run through my head, things I don't want to think about right now. So I force myself to realize and accept one final bitter truth, he never loved me." From the beginning she was told she was nothing but a mutt, an Alphas half-breed bastard. A mistake. Her father only ever did one thing right for her, he made her a machine. Taught how to kill from the moment she could walk, told it was the only thing she'd ever be good at. Her 'pack' might not have been physically abusive to her, no that was her mothers job. But they were mentally abusive and cruel, all because of something she had no control over. Her blood. When she meets her Mate, she prays for the best and expects the worst. Though her image of the worst was nothing compared to what he actually did to her. Unfortunately she didn't see it coming until it was too late. Left for dead, she waits. Cursing the Moon Goddess for her tortured life, when something unexpected happens; or someone I should say. Follow Nova as she finds out who she really is and what she was truly meant for!

In this comprehensive guide to homebrewing, Dave Miller offers expert advice on the entire brewing process. With up-to-date techniques, simple definitions for unfamiliar terminology, and helpful diagrams demonstrating proper equipment layouts and methods, Miller includes everything you need to know to brew great-tasting beer at home. Clear enough for the novice, yet thorough enough to earn a home in the libraries of accomplished brewmasters, Dave Miller’s Homebrewing Guide is packed with useful information that will inspire you to take your beer to the next level.

The seventh edition of this book is a comprehensive guide to biochemistry for medical students. Divided into six sections, the book examines in depth topics relating to chemical basics of life, metabolism, clinical and applied biochemistry, nutrition, molecular biology and hormones. New chapters have been added to this edition and each chapter includes clinical case studies to help students understand clinical relevance. A 274-page free booklet of revision exercises (9789350906378), providing essay questions, short notes, viva voce and multiple choice questions is included to help students in their exam preparation. Free online access to additional clinical cases, key concepts and an image bank is also provided. Key points Fully updated, new edition providing students with comprehensive guide to biochemistry Includes a free booklet of revision exercises and free online access Highly illustrated with nearly 1500 figures, images, tables and illustrations Previous edition published in 2010

Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer. The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, Second Edition is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field. Key Features: Offers key insights and perspectives on cancer immunology and immunotherapy treatments from renowned experts in the field Covers the basic principles and science behind cancer immunotherapy and tumor immunology Includes treatment strategies for a vast array of available immunotherapy classes and agents, such as cytokine therapies, oncolytic viruses, cancer vaccines, CAR T therapies, and combination immunotherapies Provides essential information on FDA-approved immunotherapies, including clinical management and outcome data related to response rates, risks, and toxicities Discusses special considerations for immunotherapy in the context of specific disease settings, including skin cancers, genitourinary cancers, gastrointestinal cancers, hepatocellular carcinomas, gynecologic malignancies, breast cancers, lung cancers, head and neck cancers, brain tumors, sarcomas, pediatric cancers, and treatments combined with radiation therapy Clarifies the complex regulatory aspects behind the development and approval of immunotherapy drugs

The Amazing Antioxidant Everyone Is Talking About! Are you looking for an effective way to fight the effects of aging and free radical damage? Would you like to reach and maintain your body's optimal health? There may be no stronger way than with antioxidants—and there may be no stronger antioxidant than alpha lipoic acid. This remarkable coenzyme, which occurs naturally in younger bodies but gradually diminishes with age, may very well be one of our best defenses against disease and aging. In this balanced and informative book, Burt Berkson, M.D., shows you how supplementing your diet with alpha lipoic acid might help: • Protect against heart disease • Prevent or treat complications of diabetes • Prevent the progression of Alzheimer's and Parkinson's disease • Protect against cancer and strokes • Fight chronic liver disease • Combat the aging process • And much more! Revealing the science behind this amazing antioxidant, Alpha Lipoic Acid Breakthrough provides a plan of action for improving your health starting now!

Discovering Nutrition, Fourth Edition is a student-friendly introduction to nutrition on a non-majors level. Coverage of material such as digestion, metabolism, chemistry, and life cycle nutrition is clearly written, accessible, and engaging to undergraduate students. Includes new section on diet and health, including obesity and physical activity.

"For this Second Edition many of the chapters have been updated, especially the chapters on immunology, basic microbiology, the endocrine and locomotor systems and the breast. An attempt has been made throughout to indicate the clinical relevance of the facts and the reason for learning them. There are several new contributors to the author team, all of whom are experts in their field and many of them are or have been, experienced examiners at the various UK Royal Colleges." "Although this book has been written to encompass the basic anatomy, physiology and pathology required by the syllabus of the UK Royal Colleges and the Intercollegiate Surgical Curriculum Project, it contains the necessary information required for equivalent international examinations and assessments."--BOOK JACKET.

Written with non-majors in mind, Discovering Nutrition, Sixth Edition introduces students to the fundamentals of nutrition with an engaging and personalized approach. The text focuses on teaching behavior change and personal decision making with an emphasis on how our nutritional behaviors influence lifelong personal health and wellness, while also presenting up-to-date scientific concepts in a number of innovative ways. Students will learn practical consumer-based nutrition information using the features highlighted throughout the text, including For Your Information boxes presenting controversial topics, Quick Bites offering fun facts, and the NEW feature Why Is This Important? opens each section and identifies the importance of each subject to the field.

After the death of his father, the great Alpha King, his son is filled with anger and pain, losing faith in worshipping and serving the moon goddess. Gonzalo Hemming, Alpha Prince of Poldark pack, is caught between a rock and a hard place when he mistakenly gets married to a slave girl, Ashina Diego, instead of his supposed mate. He hates this slave with every fiber of his being and would give anything to see her spend her entire life in misery. He has accused her of treason and vowed to take revenge on her, as her father murdered the great Alpha King. According to the tradition, the subjects and rulers of Poldark are not allowed to divorce. What will become of his supposed Luna? Will the prince's mate fight for her rights or allow destiny to solve the puzzle? Could this be a mistake by the moon goddess or was fate playing a quick one on him?"